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Bai Lab

Our goal is to employ cryo-EM to determine high resolution structures of important membrane protein complexes involved in cellular signaling, including cellular receptors and ion channels. We also combine structural approaches with functional studies to reveal the structure-function relationships of these membrane proteins.

  • Xiaochen Bai, Ph.D.

Bailey Lab

The Bailey lab focuses on developing gene therapies for neurological disorders. We work on monogenetic pediatric disorders, including SLC13A5 epileptic encephalopathy, multiple sulfatase deficiency, Charcot Marie Tooth disease type 4J, giant axonal neuropathy and ECHS1 deficiency.

  • Rachel Bailey, Ph.D.
Gene therapy for neurological disorders
Neuroscience

Banaszynski Lab

We study the role of chromatin regulation in cell fate decisions.

  • Laura Banaszynski, Ph.D.
Genetics, Development and Disease

Baum Lab

Our laboratory has characterized many of the transporters responsible for proximal tubule acidification and solute transport

  • Michel Baum, M.D.

Beckham Lab

The Beckham lab is a dynamic multidisciplinary laboratory that studies viral pathogenesis and neuroimmune responses.

  • J. David Beckham, M.D.

Bedimo Lab

Dr. Bedimo studies strategies for optimally managing drug-resistant HIV patients, analyzing metabolic abnormalities in HIV patients, and studying the effects of HCV co-infection. 

  • Roger Bedimo, M.D.
Highly Active Anti-retroviral Therapy HAART

Beutler Lab

We combine classical genetics with modern technology to understand human physiology and search for breakthrough treatments for diseases.

  • Bruce Beutler, M.D.
Immunology

Bezerra Lab

The Bezerra Lab current studies investigate how developmental defects increase the susceptibility of the biliary epithelium to infectious and toxic insults.

  • Jorge Bezerra, M.D.
Immunology

Bioinformatics Lab

The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.

  • Chao Xing, Ph.D., Director
bioinformatics statistical genomics statistical genetics genetics biostatistics Human Disease Mapping GWAS sequencing
Biomedical Engineering Genetics, Development and Disease

Biomolecular NMR Facility

This facility is the home to five high field solution NMR spectrometers ranging from 500 MHz to 800 MHz and a Solid State 600 MHz DNP system, primarily in support of studies of macromolecular structure, function and dynamics.

  • Jose Rizo-Rey
  • Michael Rosen
  • Kendra Frederick
  • Xuelian Luo
  • Hongtao Yu
Molecular Biophysics Neuroscience Molecular Biophysics Molecular Biophysics Molecular Biophysics

Blount Lab

Our research is largely aimed at understanding how an organism detects mechanical force.

Bowen Lab

The Bowen Lab focuses on the development of hybrid positron emission tomography (PET) (e.g. PET-CT and PET-MR) tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients.

  • Spencer Bowen, Ph.D.
Biomedical Engineering

Brekken Lab

The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.

  • Rolf A. Brekken, Ph.D.
Tumor microenvironment
Cancer Biology

Brown & Goldstein Lab

Our laboratory discovered a family of transcription factors called sterol regulatory element-binding proteins (SREBPs) that control cholesterol and fatty acid synthesis. 

  • Michael S. Brown, M.D.
  • Joseph L. Goldstein, M.D.
Biological Chemistry Cell and Molecular Biology

Brown Lab

Dr. Brown's Psychoneuroendocrine Research Program (PNE) at UT Southwestern Medical Center focuses on two different areas of research: substance abuse, particularly dual diagnoses (e.g., depression or bipolar disorder); and the effects of corticosteroids (e.g., prednisone) on mood and memory.

  • E. Sherwood Brown, M.D., Ph.D.
Clinical Psychology

Brugarolas Lab

  • To understand how kidney cancer develops at the molecular level.
  • To translate our findings into new treatments for kidney cancer patients.
  • To train the next generation of physicians and scientists.
  • James Brugarolas, M.D., Ph.D.
Cancer Biology Genetics, Development and Disease

Burgess Lab

The Burgess lab uses Nuclear Magnetic Resonance spectroscopy and Mass Spectrometry in conjunction with stable isotope (non-radioactive) tracers to study how metabolic flux is altered by disease, pharmacology, or targeted genetic interventions.

  • Shawn Burgess, Ph.D.
Biomedical Engineering

Burstein Lab

Burstein Laboratory focuses on understanding the regulation of the inflammatory response at a molecular level, and elucidating how these events may participate in human disease.

  • Ezra Burstein, M.D., Ph.D.
Inflammation Endosomal biology
Genetics, Development and Disease Immunology

Busch Lab

The Busch Lab develops optical technologies for minimally and non-invasive bedside assessment of microvascular blood flow and oxygen saturation, allowing continuous assessment of aerobic metabolism. 

  • David Busch, Ph.D.
translational neuromonitoring
Biomedical Engineering Neuroscience

Buszczak Lab

Buszczak laboratory seeks to gain new insights into mRNA translation, ribosome biogenesis and germ cell biology 

  • Michael Buszczak, Ph.D.
Germ cells Ribosomes
Cancer Biology Genetics, Development and Disease