Meet the PI

Prasanna Alluri, M.D., Ph.D.

Prasanna Alluri, M.D., Ph.D.

Prasanna Alluri, M.D., Ph.D. is a physician-scientist working at the interface of clinical oncology and translational breast cancer research. He is an Assistant Professor in the Department of Radiation Oncology. Dr. Alluri received an M.D. from the University of Minnesota and a Ph.D. in biological chemistry from UT Southwestern Medical Center at Dallas. He completed a clinical residency in radiation oncology and a research fellowship in translational oncology in the laboratory of Dr. Arul Chinnaiyan, both at the University of Michigan School.

Research Interests

Research in the Alluri Lab is focused on the following areas:

  1. Using bedside-to-bench-approaches, including next-generation clinical sequencing of patient tumors, to develop clinically relevant models of treatment resistance in breast cancer
  2. Elucidating mechanisms of treatment resistance in breast cancer
  3. High throughput screening approaches, including large-scale CRISPR and small molecule screens, to identify synthetic lethal drug targets in treatment-refractory breast cancer
  4. Metabolic imaging approaches to study radiation-induced cardiotoxicity in breast cancer patients

Clinical Interests

Dr. Alluri's clinical focus is on breast cancer, where he sees the entire spectrum of breast cancer patients – from newly diagnosed early-stage breast cancer patients seeking curative treatments to metastatic breast cancer patients looking for innovative clinical trials. Link to Dr. Alluri's clinical profile.

Honors and Awards

  • 2024: Synergy Grant for Collaborative Research Award from the Office of the Dean at UT Southwestern Medical School
  • 2024: Top Doctor in Radiation Oncology from Castle Connolly
  • 2024: Travel Award from the Eastern Cooperative Oncology Group - American College of Radiology Imaging Network (ECOG-ACRIN)
  • 2023: Nominated to Leaders in Clinical Excellence Award from UT Southwestern Medical Center
  • 2023: Breast Cancer Translational Research Award from METAvivor
  • 2023: Translational Pilot Program Award from UT Southwestern Clinical Translational Science Award Program
  • 2023: Team Science Award from UT Southwestern Clinical Translational Science Award Program
  • 2023: Collaborative Biomedical Research Award from University of Texas at Dallas
  • 2023: Castle Connolly Top Doctor in Radiation Oncology
  • 2023: Breast Cancer Translational Research Award from METAvivor
  • 2022: Top Doctor in Radiation Oncology from Castle Connolly
  • 2022: Charles Y.C. Pak Foundation Breast Cancer - Bone Initiative Research Award
  • 2021: Breast Cancer Research Program Breakthrough Award from Department of Defense
  • 2020: Early Career Investigator Award from METAVivor
  • 2019: Conquer Cancer Foundation Research Award, top abstract at the Annual Conquer Cancer Scientific and Career Development Retreat 
  • 2018: DocStar Award from Cary Council of Southwestern Medical Foundation
  • 2017: Conquer Cancer Foundation of ASCO/Breast Cancer Research Foundation, Young Investigator Award
  • 2012: American College of Surgeons Resident Research Scholar
  • 2012: Making a Difference Award, Outstanding Clinical Care
  • 2011: Making a Difference Award, Outstanding Clinical Care
  • 2008: University of Minnesota Medical School Chapter of Gold Humanism Honor Society
  • 2004: Meritorious Research in Biomedical Sciences Award, UT Southwestern Graduate School of Biomedical Sciences
  • 2004: Sigma Xi, The Scientific Research Society