Yin Lab | UT Southwestern, Dallas, Texas

We are studying how phosphatidylinositol 4,5 bisphosphate (PIP2), a membrane lipid, regulates the actin scaffold in proliferating and apoptotic cells.

We focus on the lipid kinases that synthesize PIP₂ (phosphatidylinositol phosphate 5 kinases, PIP5Ks) and PI4P (phosphatidylinositol 4 kinases, PI4Ks), as well as the regulatory proteins that respond to PIP₂ and PI4P.

View Our Research

Meet the PI

Helen Yin, Ph.D.

Principal Investigator
Professor of Physiology
Associate Dean, Office of Women’s Careers
Director, Mechanisms of Disease and Translational Science (MoDTS) Graduate Track
Co-Director, Education and Career Development, Center for Translational Medicine

Helen was born in Shanghai, China, and grew up in Hong Kong. She graduated from Mount Holyoke College summa cum laude with a B.A. in Biology and from Harvard Medical School with a Ph.D. in Physiology. Her postdoctoral fellowships were under Z.A. Cohn, M.D., (Rockefeller University) and T.P. Stossel, M.D. (Harvard Medical School and the Massachusetts General Hospital). Helen became an Associate Professor at Harvard Medical School in 1985. She joined UT Southwestern as a Professor of Physiology in 1989.