Benjamin Chen Lab

Our goal is to further delineate the mechanisms of DNA-PKcs in DNA damage repair, cell cycle checkpoints, chromosomal stability maintenance, and carcinogenesis.

Our research focus has been on the biology of the DNA-dependent protein kinase (DNA-PK), composed of the DNA-binding Ku70/80 heterodimer and the large catalytic subunit DNA-PKcs, the key regulator of the non-homolog end-joining (NHEJ) pathway for DNA double-strand break (DSB) repair.

Meet the Principal Investigator

Benjamin Chen, Ph.D.

Benjamin Chen, Ph.D.

Principal Investigator/Associate Professor
Radiation Oncology

Research Interest

  • Genomic Instability and Cancer Development
  • Radiation Biology and DNA Damage Repair
  • Tissue Stem Cell

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Meet the Team

Get to know our Principal Investigator and team of researchers.

See Lab Members
Benjamin Chen, Ph.D.


Interested in our research? Get in touch to learn more or find out ways to collaborate.

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Hypocellularity (comparison of 7 sections)