Bruce Posner, Ph.D.
Professor in Biochemistry
Before joining the faculty at UTSW, Bruce Posner, Ph.D., was a senior scientist and a principal investigator in the High Throughput Screening Center of Emphasis at Pfizer, Inc. In that capacity, he led more than 60 HTS campaigns and identified more than 20 hit-to-lead starts for early drug discovery programs. Two of these chemical series were submitted to first-in-human clinical trials. He also has expertise in informatics (data storage, management, retrieval, and visualization) and chemoinformatics, which has proven invaluable to pre-clinical drug and target discovery efforts. He has served as Director of the HTS Core at UT Southwestern since 2009. His activities include directing projects in the Core; mentoring staff scientists, postdoctoral fellows, and graduate students; co-writing grants for screening and leading discovery projects as well as shared instrumentation; managing fiscal operations and long-range planning, and co-authoring peer-reviewed papers.