Publications

Melanoma models for the next generation of therapies.

Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G, 2021 Feb Cancer Cell

Statin Intolerance, anti-HMGCR Antibodies, and Immune Checkpoint Inhibitor-Associated Myositis: A "Two-Hit" Autoimmune Toxicity or Clinical Predisposition?

von Itzstein MS, Khan S, Popat V, Lu R, Khan SA, Fattah FJ, Park JY, Bermas BL, Karp DR, Ahmed M, Saltarski JM, Gloria-McCutchen Y, Xie Y, Li QZ, Wakeland EK, Gerber DE, 2020 May Oncologist

Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor-Induced Raynaud's-Like Phenomenon.

Khan S, von Itzstein MS, Lu R, Bermas BL, Karp DR, Khan SA, Fattah FJ, Park JY, Saltarski JM, Gloria-McCutchen Y, Xie Y, Li QZ, Wakeland EK, Gerber DE, 2020 Mar Oncologist

Investigational Biomarkers for Checkpoint Inhibitor Immune-Related Adverse Event Prediction and Diagnosis.

von Itzstein MS, Khan S, Gerber DE, 2020 Jun Clin. Chem. 6 66 779-793

FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans.

Du Q, Huynh LK, Coskun F, Molina E, King MA, Raj P, Khan S, Dozmorov I, Seroogy CM, Wysocki CA, Padron GT, Yates TR, Markert ML, de la Morena MT, van Oers NS, 2019 Sep J. Clin. Invest.

MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary.

Du Q, Hoover AR, Dozmorov I, Raj P, Khan S, Molina E, Chang TC, de la Morena MT, Cleaver OB, Mendell JT, van Oers NSC, 2019 Apr Dev. Cell

Single-Cell RNA-Sequencing of Peripheral Blood Mononuclear Cells with ddSEQ.

Khan S, Kaihara KA, 2019 Methods Mol. Biol. 1979 155-176

DNA polymerase-a regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.

Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E 2016 Mar Nat. Immunol.

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.

Banchereau R, Hong S, Cantarel B, Baldwin N, Baisch J, Edens M, Cepika AM, Acs P, Turner J, Anguiano E, Vinod P, Kahn S, Obermoser G, Blankenship D, Wakeland E, Nassi L, Gotte A, Punaro M, Liu YJ, Banchereau J, Rossello-Urgell J, Wright T, Pascual V 2016 Mar Cell

Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus.

Pathak S, Kumar KR, Kanta H, Carr-Johnson F, Han J, Bashmakov A, Faure L, Ding H, Vanarsa K, Khan S, Li QZ, Chapman K, Wakeland EK, Mohan C 2016 Jan J. Immunol.

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.

Raj P, Rai E, Song R, Khan S, Wakeland BE, Viswanathan K, Arana C, Liang C, Zhang B, Dozmorov I, Carr-Johnson F, Mitrovic M, Wiley GB, Kelly JA, Lauwerys BR, Olsen NJ, Cotsapas C, Garcia CK, Wise CA, Harley JB, Nath SK, James JA, Jacob CO, Tsao BP, Pasare C, Karp DR, Li QZ, Gaffney PM, Wakeland EK 2016 Feb Elife 5

RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8.

Khan S, Kuruvilla M, Hagin D, Wakeland B, Liang C, Vishwanathan K, Gatti RA, Torgersen TR, Abraham RS, Wakeland EK, van Oers NS, de la Morena MT 2016 Feb J. Allergy Clin. Immunol.

Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice.

Hasan M, Dobbs N, Khan S, White MA, Wakeland EK, Li QZ, Yan N 2015 Oct J. Immunol.

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.

Yoon K, Lee SO, Cho SD, Kim K, Khan S, Safe S 2011 Jun Carcinogenesis 6 32 836-42

Targeting NR4A1 (TR3) in cancer cells and tumors.

Lee SO, Li X, Khan S, Safe S 2011 Feb Expert Opin. Ther. Targets 2 15 195-206

Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways.

Cho SD, Yoon K, Chintharlapalli S, Abdelrahim M, Lei P, Hamilton S, Khan S, Ramaiah SK, Safe S 2007 Jan Cancer Res. 2 67 674-83

Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells.

Khan S, Barhoumi R, Burghardt R, Liu S, Kim K, Safe S 2006 Sep Mol. Endocrinol. 9 20 2199-214

Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cells.

Khan S, Abdelrahim M, Samudio I, Safe S 2003 Jun Endocrinology 6 144 2325-35