Research

Dr. Aroumougame's Research Interests

  • DNA damage response signaling in carcinogenesis
  • DNA repair factors in immune response and immunotherapy
  • DNA replication in tumorigenesis
  • Pathophysiology of premature aging syndrome, specifically Werner Syndrome Protein
  • Radiotherapy and heart damage
  • Space radiation and astronauts' health
Werner syndrome protein and DNA replication diagram

Werner syndrome protein and DNA replication
Werner syndrome protein protects replication of genomic DNA to prevent carcinogenesis.

Ionizing tracks traversed by space radiation

Space radiation
and DNA lesions
Ionizing tracks traversed by space radiation generate complex DNA lesions in the human genome.

Workflow

Cancer therapeutics and cardiac toxicity
DNA damage response factors in cancer therapeutics-induced heart regeneration.

DNA repair factors and immunotherapy flowchart

DNA repair factors and immunotherapy
Triggering innate immune signaling to kill cancer cells in response to genotoxic cancer therapeutics.

Werner syndrome protein and DNA replication diagram
Ionizing tracks traversed by space radiation
Workflow
DNA repair factors and immunotherapy flowchart