News

September 2022

Michael Story, Ph.D., and Narasimha Karanam, Ph.D., awarded Novocure grant

Michael Story, Ph.D., and Narasimha Karanam, Ph.D., were awarded a Novocure grant for their research, "An evidence-based approach to enhancing the response of tumors to radiation, Tumor Treating Fields, and targeted agents." Their award spans July 1, 2022 - June 30, 2025.

Michael Story, Ph.D.

March 2022

Michael Story, Ph.D., spoke at the Worldwide Federation of Neuro-Oncology Societies Meeting

Dr. Story spoke at the Worldwide Federation of Neuro-Oncology Societies meeting in Seoul, Korea. His talk was entitled “Disruptive technology: the mechanism(s) of action of Tumor Treating Fields exposure."

Worldwide Federation of Neuro-Oncology Societies meeting

March 2022

Michael Story, Ph.D., spoke at the Society for Brain Mapping and Therapeutics Annual Meeting

Dr. Story spoke at the Society for Brain Mapping and Therapeutics Annual Meeting in Los Angeles. His talk was entitled "The tumoricidal mechanisms of action for Tumor Treating Fields."

Society for Brain Mapping and Therapeutics Annual Meeting

May 2021

Dr. Story's research: an experimental drug makes radiation therapy more effective, less damaging

Dr. Story's research on an experimental drug that makes radiation therapy more effective and less damaging receives national attention.

Read the press release

March 2021

Drs. Story, Saha, and Karanam granted a patent for developing a novel method of killing cancer cells

Drs. Michael Story, Debabrata Saha, and Narasimha Kumar Karanam were granted a patent for developing a novel method of killing cancer cells that combines a PARP inhibitor, such as Olaparib, with Tumor Treating Fields, which are low intensity, intermediate frequency electric fields, applied to tumors. This method is based on preclinical findings that showed synergistic cancer cell killing when Tumor Treating Fields were used in combination with a PARP inhibitor.

Learn more about this method

November 2020

2020 SNO Virtual Meeting

Drs. Karanam and Story's presentation entitled "Therapeutic implications of conditional vulnerabilities caused by TTFields exposure in novel combination therapies for non-small cell lung cancer and brain metastases from non-small cell lung cancer" was selected for on-demand oral presentation at this year's SNO Annual Meeting.

SNO Annual Meeting
Narasimha Kumar Karanam, Ph.D. with mentor Michael Story, Ph.D.

November 2020

AACR-Novocure grantees’ collaboration plants the seeds for future therapeutics

Narasimha Kumar Karanam, Ph.D., received an AACR-Novocure Career Development Award for Tumor Treating Fields Research.

Learn more about this award

October 2020

2020 ASTRO Virtual Meeting

Drs. Karanam and Story presented a poster entitled "Tumor Treating Fields Disrupt the CDK-E2F-Rb Axis: Implications for the Use of Radiation and Targeted Agents Against E2F and CDK4/6 During TTFields Treatment" at the 2020 ASTRO virtual meeting.

2020 ASTRO virtual meeting

October 2020

Published review in International Journal of Radiation Biology

"An Overview of Potential Novel Mechanisms of Action Underlying Tumor Treating Fields-Induced Cancer Cell Death and Their Clinical Implications," written by Drs. Karanam and Story, was published in the International Journal of Radiation Biology.

Read the full published review
Brock Sishc, Ph.D.

June 2020

Brock Sishc, Ph.D., hired by NASA's Johnson Space Center

Brock Sishc, Ph.D., part of UTSW since 2014, has been recruited by NASA's Johnson Space Center to serve as the cancer discipline lead within the Space Radiation Element, a part of the Human Research Program. Brock's primary role will be to support the chief and deputy element scientists in the direction and development of research goals including gaining an understanding of the risk of space radiation exposure to astronaut health.

Human Research Program
karanam-narasimha

April 2020

Narasimha Kumar Karanam, Ph.D., receives AACR-Novocure Career Development award from AACR

Narasimha Kumar Karanam, Ph.D., recently received AACR-Novocure Career Development Award from American Association for Cancer Research (AACR) which awards him a three-year grant of $225,000 to study system level effects through trans-omics approach and to find novel combination therapies together with Tumor Treating Fields.

AACR-Novocure Career Development Award

April 2020

Brock Sishc, Ph.D., awarded $30K augmentation to Story Lab NASA grant

Brock Sishc was awarded a $30K augmentation to the Story Lab's NASA grant. He will study the role of estrogen in space radiation-induced lung cancer risk in female mice.

April 2019

Michael Story, Ph.D., awarded 2019 AACR-Novocure research grant

Dr. Story was awarded an AACR-Novocure Tumor Treating Fields research grant for his work "Exploiting the conditional vulnerabilities caused by TTFields exposure" at the American Association for Cancer Research (AACR) Annual Meeting 2019 in Atlanta.

Read more about this award