Cerebral Autoregulation, Brain Perfusion, and Neurocognitive outcomes after Traumatic Brain Injury (CAPCOG-TBI)

The focus of this study is to determine whether neurodegeneration and cognitive outcomes change after a year following a moderate to severe traumatic brain injury (TBI). We would like to know if cerebral blood flow (CBF) regulation remains altered during the chronic stage in TBI survivors and if CBF regulation is associated with brain functional integrity. 

The study is funded by The National Institute of Health- Research Project Grant (R01) and is a 5-year observational study that will be enrolling from 2024-2027. 

As of June 15th, 65 patients were enrolled, 32 completed 3-month Follow-up, 19 completed 6-month Follow-up, and 7 completed 12 month follow up.

Resources

Find helpful information below in English and Spanish.

General Information (En Español)

Support Groups

  • Dallas Acquired Brain Injury Support Group for Survivors & Family
    First Tuesday of each month | 1 p.m. - 2:30 p.m.
    Email us for in-person meeting location or Zoom link.
  • Brain Injury Network
    View the ongoing list of active groups in the DFW area.
  • Texas Health and Human Services
    View the interactive map to find a group near you.
  • TBI Support Group
    First Wednesday of each month | 6:00pm-7:00pm
    Location: Baylor Scott & White-Dallas; 411 North Washington Ave. #5000, Dallas, TX 75246
    Contact: Donna Noorbakhsh
    Email: Email
    Phone: 214-820-5967
  • TBI Support Group
    Meets: 3rd Tuesday of each month, 6-7pm
    Contact: Tiffanie Morgan
    Email: Email
    Phone: (817) 433-9600
    Baylor Scott & White-Fort Worth
    6601 Harris Pkwy
    Fort Worth, TX 76132
  • Dallas – FOCUS Group at Baylor Institute for Rehabilitation
    Meets: 1st Tuesday of each month at 2 p.m.
    Contact: Laurel Stevens, MS,CCC or Karen O’Hearn, CTRS
    Phone: 214-820-9571
    Meets at: on the second floor of Baylor Institute for Rehabilitation in Conference Room C.
    Address: Dallas, Texas
    This group is for survivors, family members, and/or caregivers of TBI survivors.
  • Dallas – The Brain Injury Support Group
    Meets: Meetings are held the 2nd and 4th Wednesday of each month from 7pm-8:30pm
    Contact: Sean Godfrey
    Phone: 972-834-9057
    Meets at: Community Outreach Center
    Address: 3014 Oak Lawn Ave., Dallas, Texas 75219
  • Denton – Brain Injury Support Group
    Meets: Meets first Thursday of the month beginning at 1pm
    Contact: Denton Regional Medical Center
    Phone: (940) 384-3970
    Meets at: Community Room of the Professional Building at Denton Regional
    Address: 3535 Interstate 35 Frontage Rd, Denton, Texas 76210
  • Fort Worth Acquired Brain Injury Support Group
    Meets: 2nd Thursday of each month from 1:30pm-3:00pm
    Contact: Dorothy Conway
    Phone: 817-250-2445
    Email
    Meets at: TX Health Harris Methodist Hospital, Richardson Tower, Mabee Rehab Center Classroom
    Address: 1300 Pennsylvania Ave., Fort Worth, Texas
    Support for brain injury survivors, their family members and/or primary caregivers, by providing opportunities for peer support and education.
  • Plano – Plano Brain Injury Support Group
    Meets: Meetings are held the 1st & 3rd Tuesdays
    Contact: Jim Burrus
    Phone: 972-519-0008
    Meets at: Health South
    Address: 2800 15th Street, Plano, Texas 75075

Our Team

Principal Investigators

Rong Zang, Ph.D.

Professor
Department of Neurology, UTSW
Cognitive & Memory Disorders, Biomedical Engineering, and Internal Medicine

View faculty profile

David Zhu, Ph.D.

Professor
Department of Neuroscience, MSU
Radiology, Psychology, Electrical & Computer Engineering and Biomedical Engineering

Key Personnel

Danilo Cardim, Ph.D.

Research Instructor
Department of Neuroscience, UT Southwestern

Jill Morales

Clinical Research Coordinator
Department of Neurology, UT Southwestern

Javier Sigala Salazar, MPH

Bilingual Research Associate
Institute for Exercise and Environmental Medicine

Shotaro Saito, Ph.D

Postdoctoral Research Fellow
Institute for Exercise and Enviornmental Medicine

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Chris Reagin, B.S.N, R.N

Research Nurse
Institute for Exercise and Environmental Medicine

John Ashley, Ph.D.

Postdoctoral Research Fellow
Institute for Exercise and Environmental Medicine

Anna Tomlinson, DNP, APRN, AGACNP-BC

Nurse Practitioner
Institute for Exercise and Environmental Medicine

Margaret (Meg) McGregor, B.S.

Research Associate
Institute for Exercise and Environmental Medicine

Contact Us

  • UT Southwestern CAPCOG-TBI Study
  • 469-431-4316
  • Email