University of Texas Southwestern Labs: Where Breakthroughs Happen

A new type of developmental disability caused by mutations in a gene known as CBX1 has been discovered by a UT Southwestern Medical Center researcher and his colleagues. The findings, reported in Genetics in Medicine, offer insight into the role this gene plays in development and could eventually lead to therapies for a range of related disorders.

The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells. However, this process often goes awry and may be responsible for a new class of chromosomal abnormalities found in cancers and congenital disorders, UT Southwestern Medical Center scientists report in a new study.

The Feinstein Institutes for Medical Research has selected two scientists from UT Southwestern Medical Center, Helen H. Hobbs, M.D., and Jonathan C. Cohen, Ph.D., to receive the 10th annual Ross Prize in Molecular Medicine for groundbreaking research in dyslipidemias and metabolic liver disease.

UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.

The National Academy of Sciences elected two UT Southwestern Medical Center scientists in the fields of molecular genetics and physiology into its membership, one of the highest honors for American scientists.