We use neuroimaging, neuromodulation, and behavioral experimentation to elucidate the brain circuits and mechanisms that support language and cognition, and to understand how these circuits differ in neurodevelopmental conditions such as autism. We are particularly interested in the role of cerebro-cerebellar circuits in language and cognition across development and disorders.
The Danuser lab develops computer vision methods and mathematical models in combination with live cell imaging approaches to unveil non-genetic mechanisms of cancer metastasis and drug resistance. Specialty areas: Computer Vision, Computational Biology, Live Cell Imaging
The central goal of the Dauer Lab is to unravel the molecular and cellular mechanisms of diseases that disrupt the motor system. In exploring these diseases, we also aim to understand a fundamental question relevant to CNS disease generally: what factors determine the selective vulnerability of particular cell types or circuits to insults? Our primary focus is on Parkinson’s disease and inherited forms of dystonia. We focus our efforts on disease genes that cause these disorders, employing a range of molecular, cellular, and whole animal studies to dissect the normal role of disease proteins, and how pathogenic mutations lead to disease.
William Dauer, M.D.
parkinson's diseasecentral nervous system diseaseDystonia
The Davenport Lab is a branch of the ANSIR Lab at UTSW that focuses on quantitative methods for human brain imaging, primarily using MRI and Magnetoencephalography (MEG).
The De Brabander Lab focuses on the synthesis of complex molecular architectures, including both designed and naturally occurring substances with novel structural features and interesting biological function.
The Dean Lab aims to develop and apply cutting-edge microscopy instrumentation and analyses to gain insight into otherwise intractable biological problems.
Proper control of metabolism is required for essentially every basic biological process. Altered metabolism at the cellular level contributes to several serious diseases including inborn errors of metabolism (the result of inherited genetic defects in metabolic enzymes that lead to chemical imbalances in children) and cancer. Our laboratory seeks to characterize these metabolic disorders, understand how they compromise tissue function, develop methods to monitor metabolism in vivo and design therapies to restore normal metabolism and improve health.
The HMG CoA reductase regulatory system researched by DeBose-Boyd Lab involves a complex, multivalent feedback mechanism that is mediated by sterol and nonsterol end-products of mevalonate metabolism.
The Ding lab is led by Dr. Kan Ding, an Associate Professor and practicing neurologist who specializes in epilepsy. The lab concentrates on neurocritical care and post-traumatic epilepsy, with the goal of advancing strategies for diagnosis, treatment, and rehabilitation to improve care for those with epilepsy.