Search Labs

We are interested in understanding how animals process both external and internal sensory information to interact appropriately with their environment.

Welcome to the Le Laboratory in the Department of Dermatology and Simmons Comprehensive Cancer Center. One aim of our lab is to help train the next generation of scientists and physicians.

Our research is aimed at innovating and translating computational technology to advance biomedical research and medical diagnoses/treatments.

The Lehrman lab uses biochemical approaches to study the functions of sugars and sugar-polymers coupled to proteins and lipids, and as free molecules. Our work involves broken-cell systems, living cultured cells, and animals. This area of research, known as Glycobiology, is an emerging field that encompasses most aspects of biology and medicine.

Our mission is to improve the lives of people living with skin and musculoskeletal diseases through rigorous science and compassion.

We are interested in understanding the process of co-evolution of tumor and immune cells during cancer development, which can be tracked from clonal expansion events, together with components of the tumor microenvironment and infiltrating immune repertoire.

We are broadly interested in cellular mechanisms maintaining genome stability and their impact on human diseases, including cancer and neurodegenerative disorders.

The N-LAB's mission is to develop novel neuroimaging and neuroengineering methods to integrate molecular and system neuroscience and solve brain science problems.

The overarching goal of Wen-hong Li Lab is to investigate mechanisms responsible for maintaining islet cell function and to devise new strategies for enhancing beta cell fitness and robustness to prevent or treat diabetes.

Our lab focuses on membrane proteins in cholesterol biogenesis, transport, and signaling using multiple approaches from protein engineering, to x-ray crystallography and cryo-EM.

Our mission is to understand the most fundamental questions in cancer biology, such as tumor initiation, progession, and response to therapy, through state-of-the-art experimentation, fruitful collaborations and, above all, out-of-the box thinking to develop novel, safe(r) and more effective therapies to win the fight against cancer!

The Lin lab develops theoretical models and uses computational tools to find the performance limits of complex biological systems. 

The goal of Lin (Weichun) Lab's research is to understand how neurons establish synaptic connections during development, and how these connections are maintained throughout adulthood. Toward this goal, we are currently focusing on the following two areas of research.

The Liou Lab seeks to understand the principles underlying communication between organelles within mammalian cells.

Glen Liszczak  laboratory is exploring cellular signaling mechanisms that regulate transcription and preserve genome stability.

The Liu lab investigates genetic and environmental factors leading towards obesity and metabolic syndrome in children and adolescents.

The Liu Lab is Interested in developing and evaluating novel therapies, notably targeting tumor vasculatures.

The Liu Lab is interested in the functions and mechanism of codon usage biases, circadian clocks, and non-coding RNA

The major interest of my lab is to understand the transcriptional regulatory mechanisms involved in human diseases with a focus on cardiovascular diseases and cancer. 

Our mission is to better unravel the causes and mechanisms underlying tremor disorders as well as understand the clinical features of these disorders.

For decades, the field of tuberculosis (TB) immunology has focused on T cell mediated protection, yet Mycobacterium tuberculosis (Mtb) still impacts one in four individuals worldwide today.

The lab of Lawrence Lum, Ph.D., studies cellular signaling processes important in adult stem cell renewal and cancer.

The Luo lab studies hypoxia stress in human cancers. 

The Luo lab studies the molecular mechanisms of intracellular signal transduction, focusing on the spindle checkpoint and the Hippo tumor-suppressor pathway.

The research interests of the Lux Lab lie in the development of novel nanomedicine platforms to diagnose and treat disease in vivo noninvasively.

The Ly Laboratory studies how cell cycle defects and mitotic errors shape the complex mutational landscape of human cancer genomes.