Children with in-born errors of immunity are prone to life-threatening viral, bacterial, and fungal infections. We study the causes of their immune system problems, combining clinical insights and mouse models genocopying the various mutations. This work includes a profiling of immune responses to infections (e.g., COVID-19) in normal healthy individuals along with different patient populations (e.g. 22q11.2 deletion syndrome).
Our team at UT Southwestern is conducting the study Improving Chronic Disease Management with Pieces (IDC-Pieces) in patients with coexistent chronic kidney disease, diabetes and hypertension.
Dr. Vega and co-workers have discovered three other causes of high LDL. First, she found that some patients have abnormal LDL particles that cannot be removed from circulation because the abnormal LDL does not recognize the receptors.
The Vernino Lab focuses on the mechanisms of autoimmune disorders of the nervous system, especially those associated with neurological autoantibodies. We use a variety of techniques including histology, and immunology. This research is complemented by clinical therapeutic trials studying novel treatments for autoimmune encephalitis and autonomic disorders.
The main focus of the Vinogradov Lab is developing MRI methods that are based on the intrinsic biochemical processes and physical properties of the tissue: chemical exchange rearrangements, molecular networks, and relaxation.
Our research efforts are currently focused in four areas of cancer research.
The Volk Lab's research focuses on the hippocampus as they research how the brain balances dynamic learning and persistent memory.
Dr. Vongpatanasin studies neural control of blood pressure and the influence of various hormones and antihypertensive agents on autonomic control of blood pressure in humans.
