Vernino Lab focuses on the mechanisms of autoimmune disorders of the nervous system. We use a variety of techniques including animal physiology, cellular electrophysiology, histology, and immunology.
The immune system plays a primary role in many serious diseases of the nervous system including multiple sclerosis, myasthenia gravis, and paraneoplastic neurologic disorders. These autoimmune disorders are important because they are potentially treatable but may be undiagnosed or frequently misdiagnosed as another untreatable condition. Over the past 10 years, new laboratory (antibody) tests have been developed to help identify autoimmune neurological disorders and many clinical syndromes have been described. This is a growing and exciting area of clinical neurology.
Microscopic view of a histologic specimen Our lab has a particular interest in diseases associated with antibodies against ion channels. Voltage and ligand-gated ion channels allow nerve cells to have their unique electrical properties, and such antibodies could directly change how nerve cells function. Antibodies against the acetylcholine receptor on muscle are the cause of myasthenia gravis. Recent work in the laboratory has shown that antibodies against acetylcholine receptors on certain neurons are the cause of autoimmune autonomic neuropathy (a disease which causes severe problems with the automatic functions of the body—low blood pressure, loss of sweating, salivation, and tearing, and impaired digestion). These ion channel antibodies directly affect how nerve cells function.
In addition to myasthenia and autonomic neuropathy, ion channel autoimmunity appears to be important in other neurological disorders as well, including ataxia, seizures, memory disorders, and others. The laboratory research over the next few years will focus on characterizing several forms of ion channel autoimmunity using animal model systems in an effort to understand the immune mechanisms involved and the functional effects of antibodies on ion channel function. Furthermore, these studies of immune-mediated changes in ion channel function will improve our understanding of the role of specific ion channels in the normal nervous system and how nerve cells respond to immunological injury.
Meet the Principal Investigator
Steven Vernino, M.D., Ph.D.
Vice Chair for Education & Faculty Affairs
Professor
Endowed Title: Rex Griswold Distinguished Professorship in Multiple System Atrophy; Distinguished Teaching Professor; Dr. Bob and Jean Smith Foundation Distinguished Chair in Neuromuscular Disease Research
Department: Neurology
Lab Members
Featured Publications
Vernino S, Hopkins S, Bryarly M
2025 Apr
Clinical Autonomic Research
35
339-340
Dinov D, Nguyen L, Blackburn K, Vernino S
2025
Expert review of neurotherapeutics
Lenka A, Vernino S
2025
Clinical Autonomic Research
Baxter L, Hopkins S, O'Connor KC, Pham MC, Nowak RJ, Monson NL, Blackburn K, Hibbs RE, Vernino S, Noviello CM
2024 Nov
Journal of Neuroimmunology
396
Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study
Vernetti PM, Norcliffe-Kaufmann L, Palma JA, Biaggioni I, Shibao CA, Peltier A, Freeman R, Gibbons C, Goldstein DS, Low PA, Singer W, Coon EA, Miglis MG, Wenning GK, Fanciulli A, Vernino S, Betensky RA, Kaufmann H 2024 Jul Brain 147 2440-2448
Rozen SM, Wolfe GI, Vernino S, Raskin P, Hynan LS, Wyne K, Fulmer R, Pandian G, Sharma SK, Mohanty AJ, Sanchez CV, Hembd A, Gorman A
2024 Jul
Annals of surgery
280
35-45
Vernino S, Hopkins S, Bryarly M, Hernandez RS, Salter A
2024 Feb
Clinical Autonomic Research
34
153-163
Millar Vernetti P, Vernino S
2024 Jan
1
473-487
Golden E, Vernino S
2024 Jan
275-282
Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients with Synucleinopathies
Gibbons CH, Levine T, Adler C, Bellaire B, Wang N, Stohl J, Agarwal P, Aldridge GM, Barboi A, Evidente VG, Galasko D, Geschwind MD, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis M, Reynolds A, Sahagian GA, Saint-Hillaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Yerstein O, Freeman R 2024 JAMA 331 1298-1306
Monson N, Smith C, Greenberg H, Plumb P, Guzman A, Tse K, Chen D, Zhang W, Morgan M, Speed H, Powell C, Batra S, Cowell L, Christley S, Vernino S, Blackburn K, Greenberg B
2023 Nov
Journal of Immunology
211
1332-1339
Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation
Chlebowicz J, Russ W, Chen D, Vega A, Vernino S, White CL, Rizo J, Joachimiak LA, Diamond MI 2023 Oct Science Advances 9The need for consistent clinical definitions in autonomic medicine
Vernino S 2023 Jun Clinical Autonomic Research 33 215-216
Flanagan EP, Geschwind MD, Lopez-Chiriboga AS, Blackburn KM, Turaga S, Binks S, Zitser J, Gelfand JM, Day GS, Dunham SR, Rodenbeck SJ, Clardy SL, Solomon AJ, Pittock SJ, McKeon A, Dubey D, Zekeridou A, Toledano M, Turner LE, Vernino S, Irani SR
2023 Jan
JAMA neurology
80
30-39
Stopschinski BE, Fredrich S, Vernino S, Phillips L, Blackburn KM
2022 Dec
Neurology
99
1115-1121
Golden EP, McCreary M, Vernino S
2022 Dec
Clinical Autonomic Research
32
477-484
Fredrich S, Wang C, Narayan R, Tardo L, Blackburn KM, Vernino S
2022 Sep
Neurology: Neuroimmunology and NeuroInflammation
9
Hall J, Bourne KM, Vernino S, Hamrefors V, Kharraziha I, Nilsson J, Sheldon RS, Fedorowski A, Raj SR
2022 Aug
Circulation
146
613-622
MEN2B Masquerading as Postural Orthostatic Tachycardia Syndrome
Khan G, Giacona J, Mirfakhraee S, Vernino S, Vongpatanasin W 2022 Jul JACC: Case Reports 4 814-818
Blackburn KM, Denney DA, Hopkins SC, Vernino SA
2022 Jun
Neurology and Therapy
11
893-903
Coon EA, Golden EP, Bryarly M, McGregor T, Nguyen BN, Moutvic MA, Cutsforth-Gregory JK, Stevens PM, Chou CZ, Rhee L, Vernino S
2022 Jun
Clinical Autonomic Research
32
205-208
Brachial Plexus Tolerance to Single-Session SABR in a Pig Model
Hrycushko B, van der Kogel AJ, Phillips L, Chhabra A, Folkert MR, Sayre JW, Vernino S, Hassan-Rezaeian N, Yamada Y, Timmerman R, Medin PM 2022 Feb International Journal of Radiation Oncology Biology Physics 112 565-571
M. Blackburn K, Vernino S
2022 Jan
955-962
Blackburn KM, Vernino S
2022 Jan
109-116
Vernino S, Low PA
2022 Jan
585-589
Golden EP, Park CJ, Vernino S
2021 Dec
Autonomic Neuroscience: Basic and Clinical
236
Raj SR, Bourne KM, Stiles LE, Miglis MG, Cortez MM, Miller AJ, Freeman R, Biaggioni I, Rowe PC, Sheldon RS, Shibao CA, Diedrich A, Systrom DM, Cook GA, Doherty TA, Abdallah HI, Grubb BP, Fedorowski A, Stewart JM, Arnold AC, Pace LA, Axelsson J, Boris JR, Moak JP, Goodman BP, Chémali KR, Chung TH, Goldstein DS, Darbari A, Vernino S
2021 Nov
Autonomic Neuroscience: Basic and Clinical
235
Vernino S, Bourne KM, Stiles LE, Grubb BP, Fedorowski A, Stewart JM, Arnold AC, Pace LA, Axelsson J, Boris JR, Moak JP, Goodman BP, Chémali KR, Chung TH, Goldstein DS, Diedrich A, Miglis MG, Cortez MM, Miller AJ, Freeman R, Biaggioni I, Rowe PC, Sheldon RS, Shibao CA, Systrom DM, Cook GA, Doherty TA, Abdallah HI, Darbari A, Raj SR
2021 Nov
Autonomic Neuroscience: Basic and Clinical
235
Autoimmune encephalitis: Proposed recommendations for symptomatic and long-term management
Author Collaboration AE, Abboud H, Probasco JC, Irani S, Ances B, Benavides DR, Bradshaw M, Christo PP, Dale RC, Fernandez-Fournier M, Flanagan EP, Gadoth A, George P, Grebenciucova E, Jammoul A, Lee ST, Li Y, Matiello M, Morse AM, Rae-Grant A, Rojas G, Rossman I, Schmitt S, Venkatesan A, Vernino S, Pittock SJ, Titulaer MJ, Tarawneh R, Van Mater H, Muscal E, Ruhoy I, Anziska Y, Longbrake E, Benseler S, Wang C, Apperson M, Iorio R, Simabukuro MM, Zhong N, Rüegg S, Piquet A, Kuo J, Konuskan B, Frid E, Deng J, Mitchell W, Mooneyham GL, Estiasari R, Chiba Y, Alarcio M, Blackburn K 2021 Aug Journal of Neurology, Neurosurgery and psychiatry 92 897-907Ganglionic Acetylcholine Receptor Antibodies in Postural Tachycardia Syndrome
Bryarly M, Raj SR, Phillips L, Hynan LS, Okamoto LE, Arnold AC, Paranjape SY, Vernino M, Black BK, Vernino S 2021 Aug Neurology: Clinical Practice 11 E397-E401Autoimmune encephalitis: Proposed best practice recommendations for diagnosis and acute management
Author Collaboration AE, Abboud H, Probasco JC, Irani S, Ances B, Benavides DR, Bradshaw M, Christo PP, Dale RC, Fernandez-Fournier M, Flanagan EP, Gadoth A, George P, Grebenciucova E, Jammoul A, Lee ST, Li Y, Matiello M, Morse AM, Rae-Grant A, Rojas G, Rossman I, Schmitt S, Venkatesan A, Vernino S, Pittock SJ, Titulaer MJ, Tarawneh R, Van Mater H, Muscal E, Ruhoy I, Anziska Y, Longbrake E, Benseler S, Wang C, Apperson M, Iorio R, Simabukuro MM, Zhong N, Rüegg S, Piquet A, Kuo J, Konuskan B, Frid E, Deng J, Mitchell W, Mooneyham GL, Estiasari R, Chiba Y, Alarcio M, Blackburn K 2021 Jul Journal of Neurology, Neurosurgery and psychiatry 92 757-768
Fredrich SE, Vernino S, Blackburn KM
2021 Jun
Frontiers in Neurology
12
Hall J, Bourne KM, Sheldon RS, Vernino S, Raj V, Ng J, Okamoto LE, Arnold AC, Bryarly M, Phillips L, Paranjape SY, Raj SR
2021 Jun
Clinical Autonomic Research
31
433-441
Long-COVID postural tachycardia syndrome: an American Autonomic Society statement
Author Collaboration tA, Raj SR, Arnold AC, Barboi A, Claydon VE, Limberg JK, Lucci VE, Numan M, Peltier A, Snapper H, Vernino S 2021 Jun Clinical Autonomic Research 31 365-368
Golden E, Blackburn K, Vernino S
2021 Apr
347-357
Blackburn K, Vernino S, Sguigna P
2020 Nov
Multiple Sclerosis and Related Disorders
46
Author Collaboration tA, Figueroa JJ, Cheshire WP, Claydon VE, Norcliffe-Kaufmann L, Peltier A, Singer W, Snapper H, Vernino S, Raj SR
2020 Aug
Clinical Autonomic Research
30
295-297
Ding K, Tarumi T, Wang C, Vernino S, Zhang R, Zhu DC
2020 Jun
Brain Structure and Function
225
1575-1585
Response to: Human papillomavirus (HPV) vaccine safety concerning POTS, CRPS and related conditions
Author Collaboration tA, Barboi A, Gibbons CH, Bennaroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR 2020 Apr Clinical Autonomic Research 30 183-184
Hrycushko B, van der Kogel AJ, Phillips L, Folkert MR, Sayre JW, Vernino S, Hassan-Rezaeian N, Foster RD, Yamada Y, Timmerman R, Medin PM
2020 Apr
International Journal of Radiation Oncology Biology Physics
106
1010-1016
Blackburn KM, Ivleva EI, Weir RA, Kim M, Hopkins SC, Hudgens-Haney ME, Keedy SK, Gershon ES, Sweeney JA, Keshavan MS, Pearlson GD, Clementz BA, Tamminga CA, Vernino S
2020 Apr
Schizophrenia Research
218
318-320
Vernino S
2020 Feb
CONTINUUM Lifelong Learning in Neurology
26
44-57
Author Collaboration ob, Barboi A, Gibbons CH, Axelrod F, Benarroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR
2020 Feb
Clinical Autonomic Research
30
13-18
Blackburn KM, Kubiliun M, Harris S, Vernino S
2019 Oct
Neurogastroenterology and Motility
31
Spinal Nerve Tolerance to Single-Session Stereotactic Ablative Radiation Therapy
Hrycushko B, van der Kogel AJ, Phillips L, Folkert MR, Sayre JW, Vernino S, Hassan-Rezaeian N, Foster RD, Yamada Y, Timmerman R, Medin PM 2019 Jul International Journal of Radiation Oncology Biology Physics 104 845-851
Golden EP, Vernino S
2019 Jun
Clinical Autonomic Research
29
277-288
Postural Orthostatic Tachycardia Syndrome: JACC Focus Seminar
Bryarly M, Phillips LT, Fu Q, Vernino S, Levine BD 2019 Mar Journal of the American College of Cardiology 73 1207-1228
Author Collaboration MS, Wolfe GI, Kaminski HJ, Aban IB, Minisman G, Kuo HC, Marx A, Ströbel P, Mazia C, Oger J, Cea JG, Heckmann JM, Evoli A, Nix W, Ciafaloni E, Antonini G, Witoonpanich R, King JO, Beydoun SR, Chalk CH, Barboi AC, Amato AA, Shaibani AI, Katirji B, Lecky BR, Buckley C, Vincent A, Dias-Tosta E, Yoshikawa H, Waddington-Cruz M, Pulley MT, Rivner MH, Kostera-Pruszczyk A, Pascuzzi RM, Jackson CE, Verschuuren JJ, Massey JM, Kissel JT, Werneck LC, Benatar M, Barohn RJ, Tandan R, Mozaffar T, Silvestri NJ, Conwit R, Sonett JR, Jaretzki A, Newsom-Davis J, Pan E, Vernino S, Nations S
2019 Mar
The Lancet Neurology
18
259-268
Author Collaboration ob, Barboi A, Gibbons CH, Axelrod F, Benarroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR
2019 Jan
Autonomic Neuroscience: Basic and Clinical
Lodhi HA, Peri-Okonny PA, Schesing K, Phelps K, Ngo C, Evans H, Arbique D, Price AL, Vernino S, Phillips L, Mitchell JH, Smith SA, Yano Y, Das SR, Wang T, Vongpatanasin W
2019
Journal of the American Heart Association
8
Autoimmunity in postural orthostatic tachycardia syndrome: Current understanding
Vernino S, Stiles LE 2018 Dec Autonomic Neuroscience: Basic and Clinical 215 78-82
Hauser RA, Biaggioni I, Hewitt LA, Vernino S
2018 Nov
Movement Disorders Clinical Practice
5
627-634
Adi T, Estacion M, Schulman BR, Vernino S, Dib-Hajj SD, Waxman SG
2018 Nov
Molecular Pain
14
Seronegative autoimmune autonomic neuropathy: a distinct clinical entity
Golden EP, Bryarly MA, Vernino S 2018 Feb Clinical Autonomic Research 28 115-123
Gupta F, Kremens D, Vernino S, Karabin B
2017 Dec
Clinical Autonomic Research
27
429
Faciobrachial dystonic spells: Presenting feature of autoimmune encephalopathy
Dubey D, Alqallaf A, Warnack W, Gupta P, Harvey J, Vernino S 2017 Sep Neurology India 65 1149-1151
Gibbons CH, Schmidt P, Biaggioni I, Frazier-Mills C, Freeman R, Isaacson S, Karabin B, Kuritzky L, Lew M, Low P, Mehdirad A, Raj SR, Vernino S, Kaufmann H
2017 Aug
Journal of neurology
264
1567-1582
Gupta F, Kremens D, Vernino S, Karabin B
2017 Jul
Clinical Autonomic Research
27
9-11
Vernino S, Claassen D
2017 Jul
Clinical Autonomic Research
27
33-34
Vernino S, Lew M, Kremens D
2017 Jul
Clinical Autonomic Research
27
35-37
Neurological autoantibody prevalence in epilepsy of unknown etiology
Dubey D, Alqallaf A, Hays R, Freeman M, Chen K, Ding K, Agostini M, Vernino S 2017 Apr JAMA neurology 74 397-402Autoimmunity-associated autonomic failure with sympathetic denervation
Goldstein DS, Holmes C, Sullivan P, Donadio V, Isonaka R, Zhong E, Pourier B, Vernino S, Kopin IJ, Sharabi Y 2017 Feb Clinical Autonomic Research 27 57-62The major histocompatibility complex and antibody-mediated limbic encephalitis
Stüve O, Vernino S 2017 Feb Annals of Neurology 81 181-182Long-term safety of droxidopa in patients with symptomatic neurogenic orthostatic hypotension
Isaacson S, Vernino S, Ziemann A, Rowse GJ, Kalu U, White WB 2016 Oct Journal of the American Society of Hypertension 10 755-762
Dubey D, Farzal Z, Hays R, Brown LS, Vernino S
2016 Sep
Therapeutic Advances in Neurological Disorders
9
369-377
Diagnostic and therapeutic strategies for management of autoimmune encephalopathies
Dubey D, Blackburn K, Greenberg B, Stuve O, Vernino S 2016 Aug Expert review of neurotherapeutics 16 937-949
Jordan JT, Vernino S
2016 Apr
811-818
Chukwueke U, Vernino S
2016 Apr
103-109
Arellano B, Hussain R, Miller-Little WA, Herndon E, Lambracht-Washington D, Eagar TN, Lewis R, Healey D, Vernino S, Greenberg BM, Stüve O
2016 Apr
PloS one
11
Factors contributing to delay in diagnosis of Guillain-Barré syndrome and impact on clinical outcome
Dubey D, Kapotic M, Freeman M, Sawhney A, Rojas JC, Warnack W, Vernino S 2016 Mar Muscle and Nerve 53 384-387
Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, De Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM, Hehir MK, Hobson-Webb LD, Howard JF, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, Macgowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Shieh PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI
2016 Feb
Muscle and Nerve
53
165-168
Isaacson S, Shill HA, Vernino S, Ziemann A, Rowse GJ
2016
Journal of Parkinson's Disease
6
751-759
MSPrecise: A molecular diagnostic test for multiple sclerosis using next generation sequencing
Rounds WH, Salinas EA, Wilks TB, Levin MK, Ligocki AJ, Ionete C, Pardo CA, Vernino S, Greenberg BM, Bigwood DW, Eastman EM, Cowell LG, Monson NL 2015 Nov Gene 572 191-197
Dubey D, Sawhney A, Greenberg B, Lowden A, Warnack W, Khemani P, Stuve O, Vernino S
2015 Oct
Journal of Neuroimmunology
287
93-97
Li Y, Jammoul A, Mente K, Li J, Shields RW, Vernino S, Rae-Grant A
2015 Sep
Muscle and Nerve
52
386-391
Rituximab-based therapy and long-term control of autoimmune autonomic ganglionopathy
Gupta A, Harris S, Vernino S, Naina HV 2015 Aug Clinical Autonomic Research 25 255-258
Dubey D, Samudra N, Gupta P, Agostini M, Ding K, Van Ness PC, Vernino S, Hays R
2015 Jul
Seizure
29
143-147
Vernino S
2015 Jun
JAMA Neurology
72
630-631
Disproportionate pupillary involvement in diabetic autonomic neuropathy
Yuan D, Spaeth EB, Vernino S, Muppidi S 2014 Dec Clinical Autonomic Research 24 305-309Effectiveness of multimodality treatment for autoimmune limbic epilepsy
Dubey D, Konikkara J, Modur PN, Agostini M, Gupta P, Shu F, Vernino S 2014 Dec Epileptic Disorders 16 494-499
Muppidi S, Vernino S
2014 Oct
CONTINUUM Lifelong Learning in Neurology
20
1359-1372
Baker SK, Chow BM, Vernino SA
2014 Oct
Neurology: Neuroimmunology and NeuroInflammation
1
Battiste J, Shu F, Vernino S
2014 Jun
JAMA neurology
71
801-802
Shu F, Oberle R, Herndon E, Hatanpaa K, Battiste J, Vernino S
2014 Mar
JAMA neurology
71
360-363
Low PA, Robertson D, Gilman S, Kaufmann H, Singer W, Biaggioni I, Freeman R, Perlman S, Hauser RA, Cheshire W, Lessig S, Vernino S, Mandrekar J, Dupont WD, Chelimsky T, Galpern WR
2014 Mar
The Lancet Neurology
13
268-275
Phillips L, Vernino S
2014 Jan
2
195-203
Muppidi S, Huet BA, Tajzoy E, Scribner M, Blazek P, Spaeth EB, Frohman E, Davis S, Vernino S
2013 Dec
Clinical Autonomic Research
23
297-303
Ligocki AJ, Rounds WH, Cameron EM, Harp CT, Frohman E, Courtney AM, Vernino S, Cowell LG, Greenberg B, Monson NL
2013 Jul
Genes and Immunity
14
291-301
Navalkele DD, Georgescu MM, Burns DK, Greenberg T, Vernino S
2013 Apr
JAMA neurology
70
510-514
Vernino S
2013 Apr
Muscle and Nerve
47
475-476
Haley RW, Charuvastra E, Shell WE, Buhner DM, Marshall WW, Biggs MM, Hopkins SC, Wolfe GI, Vernino S
2013 Feb
JAMA neurology
70
191-200
Muppidi S, Vernino S
2013
Handbook of Clinical Neurology
117
321-327
Objective characterization of the relative afferent pupillary defect in MS
Blazek P, Davis SL, Greenberg B, Conger A, Conger D, Vernino S, Beh SC, Stuve O, Saidha S, Ratchford JN, Green A, Calabresi PA, Balcer LJ, Frohman TC, Frohman E 2012 Dec Journal of the Neurological Sciences 323 193-200
Sharp L, Vernino S
2012 Dec
Muscle and Nerve
46
839-840
The spectrum of clinicopathological features in pure autonomic neuropathy
Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Koyano S, Momoo T, Yuasa H, Mitake S, Higashihara M, Kaida K, Yamamoto D, Hisahara S, Shimohama S, Nakae Y, Johkura K, Vernino S, Sobue G 2012 Oct Journal of neurology 259 2067-2075Slowly progressive ataxia, neuropathy, and oculomotor dysfunction
Jordan JT, Samuel G, Vernino S, Muppidi S 2012 Oct Archives of neurology 69 1366-1371
Beh SC, Nations S, Pascual JM, Vernino S
2012 Jul
Archives of neurology
69
924-927
Sudomotor dysfunction in autoimmune autonomic ganglionopathy: A follow-up study
Kimpinski K, Iodice V, Sandroni P, Fealey RD, Vernino S, Low PA 2012 Jun Clinical Autonomic Research 22 131-136
Graves D, Vernino S
2012 May
Medical Clinics of North America
96
497-523
Singer MA, Vernino SA, Wolfe GI
2012 May
Journal of the Peripheral Nervous System
17
43-49
A unique manifestation of pupillary fatigue in autoimmune autonomic ganglionopathy
Muppidi S, Scribner M, Gibbons CH, Adams-Huet B, Spaeth EB, Vernino S 2012 May Archives of neurology 69 644-648Progressive weakness with respiratory failure in a patient with sarcoidosis
Chaudhry P, Herndon E, Vernino S, Muppidi S 2012 Apr Archives of neurology 69 534-537Autoimmune autonomic ganglionopathy with reversible cognitive impairment
Gibbons CH, Centi J, Vernino S, Freeman R 2012 Apr Archives of neurology 69 461-466Clinical reasoning: A 41-year-old comatose man with absent brainstem reflexes
Beh SC, Vernino S, Warnack WR 2012 Feb Neurology 78 e42-e45
Vernino S, Low PA
2012
489-492
Sharp L, Pride L, Mathis D, Raisanen JM, Vernino S
2011 Dec
Archives of neurology
68
1599-1602
Vernino S
2011 Dec
Archives of neurology
68
Muppidi S, Gupta PK, Vernino S
2011 Oct
Neurology
77
1577-1579
Tajzoy E, Mukherjee S, Vernino S
2011 Apr
Archives of neurology
68
540-541
Vernino S
2011
Handbook of Clinical Neurology
103
215-223
Winston N, Vernino S
2010 Oct
Current opinion in neurology
23
514-518
Isolated neck extensor myopathy: Is it responsive to immunotherapy?
Muppidi S, Saperstein DS, Shaibani A, Nations SP, Vernino S, Wolfe GI 2010 Sep Journal of Clinical Neuromuscular Disease 12 26-29Slowly progressive autonomic neuropathy with antiganglionic acetylcholine receptor antibody
Koike H, Koyano S, Morozumi S, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Vernino S, Sobue G 2010 May Journal of Neurology, Neurosurgery and psychiatry 81 586-587
Wang Z, Low PA, Vernino S
2010 Mar
Experimental Neurology
222
114-119
Progress in the management of paraneoplastic neurological disorders
Sadeghian H, Vernino S 2010 Jan Therapeutic Advances in Neurological Disorders 3 43-52
Matsui N, Mitsui T, Ohshima Y, Yokoi K, Kunishige M, Yagi F, Vernino S, Matsumoto T, Kaji R
2010
Internal Medicine
49
73-77
Direct and consensual murine pupillary reflex metrics: Establishing normative values
Hussain RZ, Hopkins SC, Frohman EM, Eagar TN, Cravens PC, Greenberg BM, Vernino S, Stüve O 2009 Dec Autonomic Neuroscience: Basic and Clinical 151 164-167Sudomotor dysfunction in autoimmune autonomic ganglionopathy
Kimpinski K, Iodice V, Sandroni P, Fealey RD, Vernino S, Low PA 2009 Nov Neurology 73 1501-1506Multifocal paraneoplastic cortical encephalitis associated with myasthenia gravis and thymoma
Hammoud K, Kandimala G, Warnack W, Vernino S 2009 Nov Archives of neurology 66 1407-1409
Kimpinski K, Iodice V, Vernino S, Sandroni P, Low PA
2009 Oct
Autonomic Neuroscience: Basic and Clinical
150
136-139
Autoimmune autonomic ganglionopathy: Treatment by plasma exchanges and rituximab
Imrich R, Vernino S, Eldadah BA, Holmes C, Goldstein DS 2009 Aug Clinical Autonomic Research 19 259-262
Iodice V, Kimpinski K, Vernino S, Sandroni P, Fealey RD, Low PA
2009 Jun
Neurology
72
2002-2008
Special section on autoimmune autonomic ganglionopathy. Editorial.
Vernino S 2009 Mar Autonomic neuroscience : basic & clinical 146 1-2
Kondo T, Inoue H, Usui T, Mimori T, Tomimoto H, Vernino S, Takahashi R
2009 Mar
Autonomic Neuroscience: Basic and Clinical
146
33-35
Vernino S
2009 Mar
Autonomic Neuroscience: Basic and Clinical
146
1-2
Iodice V, Kimpinski K, Vernino S, Sandroni P, Low PA
2009 Mar
Autonomic Neuroscience: Basic and Clinical
146
22-25
Autonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy
Vernino S, Hopkins S, Wang Z 2009 Mar Autonomic Neuroscience: Basic and Clinical 146 3-7Autoimmune autonomic ganglionopathy with late-onset encephalopathy
Baker SK, Morillo C, Vernino S 2009 Mar Autonomic Neuroscience: Basic and Clinical 146 29-32Antibody testing as a diagnostic tool in autonomic disorders.
Vernino S 2009 Feb Clinical autonomic research : official journal of the Clinical Autonomic Research Society 19 13-19Paraneoplastic disorders affecting the neuromuscular junction or anterior horn cell
Vernino S 2009 Feb CONTINUUM Lifelong Learning in Neurology 15 132-146
Winston N, Vernino S
2009
Frontiers of Neurology and Neuroscience
26
85-93
Vernino S, Low PA
2009
785-789
Prevalence and mechanism of bladder dysfunction in Guillain-Barré syndrome
Sakakibara R, Uchiyama T, Kuwabara S, Mori M, Ito T, Yamamoto T, Awa Y, Yamaguchi C, Yuki N, Vernino S, Kishi M, Shirai K 2009 Neurourology and urodynamics 28 432-437Characterization of ganglionic acetylcholine receptor autoantibodies
Vernino S, Lindstrom J, Hopkins S, Wang Z, Low PA 2008 Jun Journal of Neuroimmunology 197 63-69
Vernino S
2008 Jun
124-128
Invited Article: Autonomic ganglia: Target and novel therapeutic tool
Vernino S, Sandroni P, Singer W, Low PA 2008 May Neurology 70 1926-1932Propofol for stiff-person syndrome: Learning new tricks from an old dog
Vernino S, McEvoy K 2008 Apr Neurology 70 1584-1585Antibodies to muscle and ganglionic acetylcholine receptors (AchR) in celiac disease
Briani C, Doria A, Ruggero S, Toffanin E, Luca M, Albergoni MP, D'Odorico A, Grassivaro F, Lucchetta M, De Lazzari F, Balzani I, Battistin L, Vernino S 2008 Feb Autoimmunity 41 100-104Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy
Gibbons CH, Vernino SA, Freeman R 2008 Feb Archives of neurology 65 213-217
Vernino S, Lindell EP
2008
600-605
Vernino S, Lindell EP
2008
85-89
Chapter 14 Peripheral nerve hyperexcitability and the neuromuscular junction
Vernino S 2008 Handbook of Clinical Neurology 91 433-443Dysfunction of the pupillary light reflex in experimental autoimmune autonomic ganglionopathy
Mukherjee S, Vernino S 2007 Dec Autonomic Neuroscience: Basic and Clinical 137 19-26
Vernino S, Dalmau J
2007 Dec
163-169
Vernino S, Low PA
2007 Dec
979-986
Vernino S, Freeman R
2007 Dec
CONTINUUM Lifelong Learning in Neurology
13
89-110
Kyoung MC, Zhu J, Stoltz GJ, Vernino S, Camilleri M, Szurszewski JH, Gibbons SJ, Farrugia G
2007 Nov
American Journal of Physiology - Gastrointestinal and Liver Physiology
293
G1039-G1045
Ogata Y, Charlesworth MC, Higgins L, Keegan BM, Vernino S, Muddiman DC
2007 Oct
Proteomics
7
3726-3734
EBV-associated lymphoproliferative disorder of CNS associated with the use of mycophenolate mofetil
O'Neill BP, Vernino S, Dogan A, Giannini C 2007 Jul Neuro-oncology 9 364-369
Vernino S, Geschwind M, Boeve B
2007 May
Neurologist
13
140-147
Autoimmune autonomic ganglionopathy: IgG effects on ganglionic acetylcholine receptor current
Wang Z, Low PA, Jordan J, Freeman R, Gibbons CH, Schroeder C, Sandroni P, Vernino S 2007 May Neurology 68 1917-1921
Vernino S
2007 Apr
Neurotherapeutics
4
305-314
Postural orthostatic tachycardia syndrome: The Mayo Clinic experience
Thieben MJ, Sandroni P, Sletten DM, Benrud-Larson LM, Fealey RD, Vernino S, Lennon VA, Shen WK, Low PA 2007 Mar Mayo Clinic Proceedings 82 308-313
Vernino S, Wolfe GI
2007 Feb
Neurologic Clinics
25
29-46
Vernino S, Low PA
2007
979-986
Vernino S
2006 May
Current neurology and neuroscience reports
6
193-199
Steroid-responsive encephalopathy associated with autoimmune thyroiditis
Castillo P, Woodruff B, Caselli R, Vernino S, Lucchinetti C, Swanson J, Noseworthy J, Aksamit A, Carter J, Sirven J, Hunder G, Fatourechi V, Mokri B, Drubach D, Pittock S, Lennon V, Boeve B 2006 Feb Archives of neurology 63 197-202
Vernino S, Dalmau J
2006 Jan
163-169
Vernino S
2005 Dec
Neurology
65
1688-1689
Schroeder C, Vernino S, Birkenfeld AL, Tank J, Heusser K, Lipp A, Benter T, Lindschau C, Kettritz R, Luft FC, Jordan J
2005 Oct
New England Journal of Medicine
353
1585-1590
L-DOPS therapy for refractory orthostatic hypotension in autoimmune autonomic neuropathy
Gibbons CH, Vernino SA, Kaufmann H, Freeman R 2005 Oct Neurology 65 1104-1106Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil
Vernino S, Salomao DR, Habermann TM, O'Neill BP 2005 Aug Neurology 65 639-641Speech and language findings associated with paraneoplastic cerebellar degeneration
Paslawski T, Duffy JR, Vernino S 2005 Aug American Journal of Speech-Language Pathology 14 200-207
Josephs KA, Silber MH, Fealey RD, Nippoldt TB, Auger RG, Vernino S
2004 Dec
Journal of Clinical Neurophysiology
21
440-445
Autoantibody profiles and neurological correlations of thymoma
Vernino S, Lennon VA 2004 Nov Clinical Cancer Research 10 7270-7275
Vernino S, Ermilov LG, Sha L, Szurszewski JH, Low PA, Lennon VA
2004 Aug
Journal of Neuroscience
24
7037-7042
From parallel to perpendicular: Getting "straightened out" with levodopa therapy [2]
Glynn SM, Pittock SJ, Vernino SA 2004 Jun Mayo Clinic Proceedings 79 828-829
Vernino S, Low PA, Lennon VA
2004 May
324-327
Vernino S
2004 May
208-210
Kumar N, Crum B, Petersen RC, Vernino SA, Ahlskog JE
2004 May
Archives of neurology
61
762-766
Potentially reversible autoimmune limbic encephalitis with neuronal potassium channel antibody
Thieben MJ, Lennon VA, Boeve BF, Aksamit AJ, Keegan M, Vernino S 2004 Apr Neurology 62 1177-1182Immunomodulatory treatment trial for paraneoplastic neurological disorders
Vernino S, O'Neill BP, Marks RS, O'Fallon JR, Kimmel DW 2004 Jan Neuro-oncology 6 55-62
Sandroni P, Vernino S, Klein CM, Lennon VA, Benrud-Larson L, Sletten D, Low PA
2004 Jan
Archives of neurology
61
44-48
Myasthenia gravis, thymoma, and intestinal pseudo-obstruction
Rakocevic G, Barohn R, McVey AL, Damjanov I, Morte PD, Vernino S, Lennon V 2003 Dec Journal of Clinical Neuromuscular Disease 5 93-95
Lawn ND, Westmoreland BF, Kiely MJ, Lennon VA, Vernino S
2003 Nov
Mayo Clinic Proceedings
78
1363-1368
Vernino S, Low PA, Lennon VA
2003 Sep
Journal of neurophysiology
90
2053-2059
Cause-specific mortality after first cerebral infarction: A population-based study
Vernino S, Brown RD, Sejvar JJ, Sicks JD, Petty GW, O'Fallon MW 2003 Aug Stroke 34 1828-1832Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K+ channel antibodies
Oh SJ, Alapati A, Claussen GC, Vernino S 2003 Jun Muscle and Nerve 27 757-760
Low PA, Vernino S, Suarez G
2003 Jun
Muscle and Nerve
27
646-661
Klein CM, Vernino S, Lennon VA, Sandroni P, Fealey RD, Benrud-Larson L, Sletten D, Low PA
2003 Jun
Annals of Neurology
53
752-758
Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease
Lennon VA, Ermilov LG, Szurszewski JH, Vernino S 2003 Mar Journal of Clinical Investigation 111 907-913Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease
Lennon VA, Ermilov LG, Szurszewski JH, Vernino S 2003 Mar Journal of Clinical Investigation 111 907-913
Vernino S, Lennon VA
2003
Annals of the New York Academy of Sciences
998
211-214
Muscle and neuronal autoantibody markers of thymoma: Neurological correlations
Vernino S, Lennon VA 2003 Annals of the New York Academy of Sciences 998 359-361
Vernino S, Lennon VA
2002 Nov
Muscle and Nerve
26
702-707
Paraneoplastic neurological autoimmunity associated with ANNA-1 autoantibody and thymoma
Vernino S, Eggenberger ER, Rogers LR, Lennon VA 2002 Sep Neurology 59 929-932
Goldstein DS, Holmes C, Dendi R, Li ST, Brentzel S, Vernino S
2002
Clinical Autonomic Research
12
281-285
Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma
Vernino S, Tuite P, Adler CH, Meschia JF, Boeve BF, Boasberg P, Parisi JE, Lennon VA 2002 Annals of Neurology 51 625-630Persistent facial myokymia associated with K+ channel antibodies
Gutmann L, Tellers JG, Vernino S 2001 Nov Neurology 57 1707-1708
Vernino S, Cheshire WP, Lennon VA
2001 May
Autonomic Neuroscience: Basic and Clinical
88
187-192
Paraneoplastic and metastatic neurologic complications of Merkel cell carcinoma
Eggers SD, Salomao DR, Dinapoli RP, Vernino S 2001 Mayo Clinic Proceedings 76 327-330ANNA-3 anti-neuronal nuclear antibody: Marker of lung cancer-related autoimmunity
Chan KH, Vernino S, Lennon VA 2001 Annals of Neurology 50 301-311Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neukopathies
Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA 2000 Sep New England Journal of Medicine 343 847-855New Purkinje cell antibody (PCA-2): Marker of lung cancer-related neurological autoimmunity
Vernino S, Lennon VA 2000 Annals of Neurology 47 297-305Fulminant autoimmune cortical encephalitis associated with thymoma treated with plasma exchange
Rickman OB, Parisi JE, Yu Z, Lennon VA, Vernino S 2000 Mayo Clinic Proceedings 75 1321-1326Myasthenia, thymoma, presynaptic antibodies, and a continuum of neuromuscular hyperexcitability
Vernino S, Auger RG, Emslie-Smith AM, Harper CM, Lennon VA 1999 Oct Neurology 53 1233-1239Coma in fulminant pneumococcal meningitis: New MRI observations
Vernino S, Wijdicks EF, McGough PF 1998 Oct Neurology 51 1200-1202
Vernino S, Adamski J, Kryzer TJ, Fealey RD, Lennon VA
1998 Jun
Neurology
50
1806-1813
Vernino SA, Moder KG
1996
Mayo Clinic Proceedings
71
485-488
Postpartum thrombotic thrombocytopenic purpura complicated by Budd-Chiari syndrome
Hsu HW, Belfort MA, Vernino S, Moake JL, Moise KJ 1995 Obstetrics and gynecology 85 839-843
Vernino S, Rogers M, Radcliffe KA, Dani JA
1994 Sep
Journal of Neuroscience
14
5514-5524
Functional diversity of neuronal nicotinic acetylcholine receptors
Patrick J, Sequela P, Vernino S, Amador M, Luetje C, Dani JA 1993 Jan Progress in Brain Research 98 113-120Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors
Vernino S, Amador M, Luetje CW, Patrick J, Dani JA 1992 Jan Neuron 8 127-134
Vernino S, Jericevic Ž, Wiese BA, Smith LC
1989 Dec
Proceedings of SPIE - The International Society for Optical Engineering
1161
236-246
Contact Us
Steven Vernino, M.D., Ph.D.
Professor of Neurology
Phone: 214-648-8816
Fax: 214-648-9129
Lab: 214-648-9275
Mailing Address
5323 Harry Hines Boulevard
Dallas, Texas 75390-8869
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