Vernino Lab focuses on the mechanisms of autoimmune disorders of the nervous system. We use a variety of techniques including animal physiology, cellular electrophysiology, histology, and immunology.
The immune system plays a primary role in many serious diseases of the nervous system including multiple sclerosis, myasthenia gravis, and paraneoplastic neurologic disorders. These autoimmune disorders are important because they are potentially treatable but may be undiagnosed or frequently misdiagnosed as another untreatable condition. Over the past 10 years, new laboratory (antibody) tests have been developed to help identify autoimmune neurological disorders and many clinical syndromes have been described. This is a growing and exciting area of clinical neurology.
Microscopic view of a histologic specimen Our lab has a particular interest in diseases associated with antibodies against ion channels. Voltage and ligand-gated ion channels allow nerve cells to have their unique electrical properties, and such antibodies could directly change how nerve cells function. Antibodies against the acetylcholine receptor on muscle are the cause of myasthenia gravis. Recent work in the laboratory has shown that antibodies against acetylcholine receptors on certain neurons are the cause of autoimmune autonomic neuropathy (a disease which causes severe problems with the automatic functions of the body—low blood pressure, loss of sweating, salivation, and tearing, and impaired digestion). These ion channel antibodies directly affect how nerve cells function.
In addition to myasthenia and autonomic neuropathy, ion channel autoimmunity appears to be important in other neurological disorders as well, including ataxia, seizures, memory disorders, and others. The laboratory research over the next few years will focus on characterizing several forms of ion channel autoimmunity using animal model systems in an effort to understand the immune mechanisms involved and the functional effects of antibodies on ion channel function. Furthermore, these studies of immune-mediated changes in ion channel function will improve our understanding of the role of specific ion channels in the normal nervous system and how nerve cells respond to immunological injury.
Meet the Principal Investigator
Steven Vernino, M.D., Ph.D.
Vice Chair for Education & Faculty Affairs
Professor
Endowed Title: Rex Griswold Distinguished Professorship in Multiple System Atrophy; Distinguished Teaching Professor; Dr. Bob and Jean Smith Foundation Distinguished Chair in Neuromuscular Disease Research
Department: Neurology
Lab Members
Featured Publications
Ganglionic Acetylcholine Receptor Antibodies in Postural Tachycardia Syndrome.
Bryarly M, Raj SR, Phillips L, Hynan LS, Okamoto LE, Arnold AC, Paranjape SY, Vernino M, Black BK, Vernino S, 2021 Aug Neurol Clin Pract 4 11 e397-e401
Blackburn KM, Ivleva EI, Weir RA, Kim M, Hopkins SC, Hudgens-Haney ME, Keedy SK, Gershon ES, Sweeney JA, Keshavan MS, Pearlson GD, Clementz BA, Tamminga CA, Vernino S,
2020 Jan
Schizophr. Res.
Neurological Autoantibody Prevalence in Epilepsy of Unknown Etiology.
Dubey D, Alqallaf A, Hays R, Freeman M, Chen K, Ding K, Agostini M, Vernino S 2017 Feb JAMA NeurolSeronegative autoimmune autonomic neuropathy: a distinct clinical entity.
Golden EP, Bryarly MA, Vernino S 2017 Dec Clin. Auton. Res.A Unique Manifestation of Pupillary Fatigue in Autoimmune Autonomic Ganglionopathy.
Muppidi S, Scribner M, Gibbons CH, Adams-Huet B, Spaeth EB, Vernino S 2012 May Arch. Neurol. 5 69 644-8
Wang Z, Low PA, Vernino S
2010 Mar
Exp. Neurol.
1
222
114-9
Autonomic ganglia, acetylcholine receptor antibodies, and autoimmune ganglionopathy.
Vernino S, Hopkins S, Wang Z 2009 Mar Auton Neurosci 1-2 146 3-7Characterization of ganglionic acetylcholine receptor autoantibodies.
Vernino S, Lindstrom J, Hopkins S, Wang Z, Low PA 2008 Jun J. Neuroimmunol. 1 197 63-9Autoimmune autonomic ganglionopathy: IgG effects on ganglionic acetylcholine receptor current.
Wang Z, Low PA, Jordan J, Freeman R, Gibbons CH, Schroeder C, Sandroni P, Vernino S 2007 May Neurology 22 68 1917-21
Vernino S, Geschwind M, Boeve B
2007 May
Neurologist
3
13
140-7
Schroeder C, Vernino S, Birkenfeld AL, Tank J, Heusser K, Lipp A., Benter T., Lindschau C., Kettritz R, Luft FC, Jordan J
2005
353
1585-1590
Vernino S, Ermilov L, Sha L, Szurszewski JF, Low PA, Lennon VA
2004
24(32)
7037-7042
Reversible autoimmune limbic encephalitis associated with potassium channel antibodies
Thieben MJ, Boeve BF, Aksamit AJ, Keegan BM, Lennon VA, Vernino S 2004 62 1177-1182Immunomodulatory treatment trial for paraneoplastic neurological disorders
Vernino S, O’Neill BP, Marks RS, O’Fallon JR, Kimmel DW 2004 6 55-62Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies.
Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA 2000 Sep N. Engl. J. Med. 12 343 847-55Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies
Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA 2000 21;343(12) 847-55Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management.
Abboud H, Probasco J, Irani SR, Ances B, Benavides DR, Bradshaw M, Christo PP, Dale RC, Fernandez-Fournier M, Flanagan EP, Gadoth A, George P, Grebenciucova E, Jammoul A, Lee ST, Li Y, Matiello M, Morse AM, Rae-Grant A, Rojas G, Rossman I, Schmitt S, Venkatesan A, Vernino S, Pittock SJ, Titulaer M, 2021 Mar J Neurol Neurosurg Psychiatry
Raj SR, Bourne KM, Stiles LE, Miglis MG, Cortez MM, Miller AJ, Freeman R, Biaggioni I, Rowe PC, Sheldon RS, Shibao CA, Diedrich A, Systrom DM, Cook GA, Doherty TA, Abdallah HI, Grubb BP, Fedorowski A, Stewart JM, Arnold AC, Pace LA, Axelsson J, Boris JR, Moak JP, Goodman BP, Chémali KR, Chung TH, Goldstein DS, Darbari A, Vernino S,
2021 Jun
Auton Neurosci
102836
Hall J, Bourne KM, Sheldon RS, Vernino S, Raj V, Ng J, Okamoto LE, Arnold AC, Bryarly M, Phillips L, Paranjape SY, Raj SR,
2021 Jun
Clin Auton Res
3
31
433-441
Vernino S, Bourne KM, Stiles LE, Grubb BP, Fedorowski A, Stewart JM, Arnold AC, Pace LA, Axelsson J, Boris JR, Moak JP, Goodman BP, Chémali KR, Chung TH, Goldstein DS, Diedrich A, Miglis MG, Cortez MM, Miller AJ, Freeman R, Biaggioni I, Rowe PC, Sheldon RS, Shibao CA, Systrom DM, Cook GA, Doherty TA, Abdallah HI, Darbari A, Raj SR,
2021 Jun
Auton Neurosci
102828
Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management.
Abboud H, Probasco JC, Irani S, Ances B, Benavides DR, Bradshaw M, Christo PP, Dale RC, Fernandez-Fournier M, Flanagan EP, Gadoth A, George P, Grebenciucova E, Jammoul A, Lee ST, Li Y, Matiello M, Morse AM, Rae-Grant A, Rojas G, Rossman I, Schmitt S, Venkatesan A, Vernino S, Pittock SJ, Titulaer MJ, 2021 Jul J Neurol Neurosurg Psychiatry 7 92 757-768Long-COVID postural tachycardia syndrome: an American Autonomic Society statement.
Raj SR, Arnold AC, Barboi A, Claydon VE, Limberg JK, Lucci VM, Numan M, Peltier A, Snapper H, Vernino S, 2021 06 Clin Auton Res 3 31 365-368
Fredrich SE, Vernino S, Blackburn KM,
2021
Front Neurol
12
690415
Blackburn K, Vernino S, Sguigna P,
2020 Nov
Mult Scler Relat Disord
46
102460
Hrycushko B, van der Kogel AJ, Phillips L, Folkert M, Sayre JW, Vernino S, Hassan-Rezaeian N, Foster RD, Yamada Y, Timmerman R, Medin PM,
2020 Jan
Int. J. Radiat. Oncol. Biol. Phys.
Barboi A, Gibbons CH, Axelrod F, Benarroch EE, Biaggioni I, Chapleau MW, Chelimsky G, Chelimsky T, Cheshire WP, Claydon VE, Freeman R, Goldstein DS, Joyner MJ, Kaufmann H, Low PA, Norcliffe-Kaufmann L, Robertson D, Shibao CA, Singer W, Snapper H, Vernino S, Raj SR,
2020 Jan
Auton Neurosci
223
102550
Vernino S,
2020 Feb
Continuum (Minneap Minn)
1
26
44-57
Ding K, Tarumi T, Wang C, Vernino S, Zhang R, Zhu DC,
2020 Apr
Brain Struct Funct
Golden EP, Vernino S,
2019 May
Clin. Auton. Res.
Postural Orthostatic Tachycardia Syndrome: JACC Focus Seminar.
Bryarly M, Phillips LT, Fu Q, Vernino S, Levine BD, 2019 Mar J. Am. Coll. Cardiol. 10 73 1207-1228
Blackburn KM, Kubiliun M, Harris S, Vernino S,
2019 Apr
Neurogastroenterol. Motil.
e13611
Spinal nerve tolerance to single-session stereotactic ablative radiotherapy (SAbR).
Hrycushko B, van der Kogel AJ, Phillips L, Folkert M, Sayre JW, Vernino S, Hassan-Rezaeian N, Foster RD, Yamada Y, Timmerman R, Medin PM, 2019 Apr Int. J. Radiat. Oncol. Biol. Phys.
Lodhi HA, Peri-Okonny PA, Schesing K, Phelps K, Ngo C, Evans H, Arbique D, Price AL, Vernino S, Phillips L, Mitchell JH, Smith SA, Yano Y, Das SR, Wang T, Vongpatanasin W,
2019 Apr
J Am Heart Assoc
7
8
e010161
Hauser RA, Biaggioni I, Hewitt LA, Vernino S
2018 Nov-Dec
Mov Disord Clin Pract
6
5
627-634
1.7 mutation in a carbamazepine-responsive patient with adult-onset painful peripheral neuropathy.
Adi T, Estacion M, Schulman BR, Vernino S, Dib-Hajj SD, Waxman SG 2018 Jan-Dec Mol Pain 14 1744806918815007Autoimmunity in postural orthostatic tachycardia syndrome: Current understanding.
Vernino S, Stiles LE 2018 Apr Auton NeurosciFaciobrachial dystonic spells: Presenting feature of autoimmune encephalopathy.
Dubey D, Alqallaf A, Warnack W, Gupta P, Harvey J, Vernino S 2017 Sep-Oct Neurol India 5 65 1149-1151
Vernino S, Lew M, Kremens D
2017 Jun
Clin. Auton. Res.
Gupta F, Kremens D, Vernino S, Karabin B
2017 Jul
Clin. Auton. Res.
Suppl 1
27
9-11
Vernino S, Claassen D
2017 Jul
Clin. Auton. Res.
Suppl 1
27
33-34
Gibbons CH, Schmidt P, Biaggioni I, Frazier-Mills C, Freeman R, Isaacson S, Karabin B, Kuritzky L, Lew M, Low P, Mehdirad A, Raj SR, Vernino S, Kaufmann H
2017 Jan
J. Neurol.
Isaacson S, Shill HA, Vernino S, Ziemann A, Rowse GJ
2016 Sep
J Parkinsons Dis
Dubey D, Farzal Z, Hays R, Brown LS, Vernino S
2016 Sep
Ther Adv Neurol Disord
5
9
369-77
Spinal Nerve Tolerance to Single-Session Stereotactic Ablative Radiation Therapy (SABR).
Medin PM, Hrycushko BA, Vernino S, Foster RD, Sayre J, Yamada Y, Van Der Kogel AJ 2016 Oct Int. J. Radiat. Oncol. Biol. Phys. 2S 96 S216Autoimmunity-associated autonomic failure with sympathetic denervation.
Goldstein DS, Holmes C, Sullivan P, Donadio V, Isonaka R, Zhong E, Pourier B, Vernino S, Kopin IJ, Sharabi Y 2016 Nov Clin. Auton. Res.Diagnostic and therapeutic strategies for management of autoimmune encephalopathies.
Dubey D, Blackburn K, Greenberg B, Stuve O, Vernino S 2016 May Expert Rev Neurother 1-13The major histocompatibility complex and antibody-mediated limbic encephalitis.
Stuve O, Vernino S 2016 Dec Ann. Neurol.Long-term safety of droxidopa in patients with symptomatic neurogenic orthostatic hypotension.
Isaacson S, Vernino S, Ziemann A, Rowse GJ, Kalu U, White WB 2016 Aug J Am Soc Hypertens
Arellano B, Hussain R, Miller-Little WA, Herndon E, Lambracht-Washington D, Eagar TN, Lewis R, Healey D, Vernino S, Greenberg BM, Stüve O
2016
PLoS ONE
4
11
e0152720
Dubey D, Sawhney A, Greenberg B, Lowden A, Warnack W, Khemani P, Stuve O, Vernino S
2015 Oct
J. Neuroimmunol.
287
93-7
Dubey D, Samudra N, Gupta P, Agostini M, Ding K, Van Ness PC, Vernino S, Hays R
2015 Jul
Seizure
29
143-7
Dubey D, Kapotic M, Freeman M, Sawhney A, Rojas-Martinez J, Warnack W, Vernino S
2015 Jul
Muscle Nerve
MSPrecise: A molecular diagnostic test for multiple sclerosis using next generation sequencing.
Rounds WH, Salinas EA, Wilks TB, Levin MK, Ligocki AJ, Ionete C, Pardo CA, Vernino S, Greenberg BM, Bigwood DW, Eastman EM, Cowell LG, Monson NL 2015 Jul Gene
Burns TM, Smith GA, Allen JA, Amato AA, Arnold WD, Barohn R, Benatar M, Bird SJ, Bromberg M, Chahin N, Ciafaloni E, Cohen JA, Corse A, Crum BA, David WS, Dimberg E, De Sousa EA, Donofrio PD, Dyck PJ, Engel AG, Ensrud ER, Ferrante M, Freimer M, Gable KL, Gibson S, Gilchrist JM, Goldstein JM, Gooch CL, Goodman BP, Gorelov D, Gospe SM, Goyal NA, Guidon AC, Guptill JT, Gutmann L, Gutmann L, Gwathmey K, Harati Y, Harper CM, Hehir MK, Hobson-Webb LD, Howard JF, Jackson CE, Johnson N, Jones SM, Juel VC, Kaminski HJ, Karam C, Kennelly KD, Khella S, Khoury J, Kincaid JC, Kissel JT, Kolb N, Lacomis D, Ladha S, Larriviere D, Lewis RA, Li Y, Litchy WJ, Logigian E, Lou JS, MacGowen DJ, Maselli R, Massey JM, Mauermann ML, Mathews KD, Meriggioli MN, Miller RG, Moon JS, Mozaffar T, Nations SP, Nowak RJ, Ostrow LW, Pascuzzi RM, Peltier A, Ruzhansky K, Richman DP, Ross MA, Rubin DI, Russell JA, Sachs GM, Salajegheh MK, Saperstein DS, Scelsa S, Selcen D, Shaibani A, Sheih PB, Silvestri NJ, Singleton JR, Smith BE, So YT, Solorzano G, Sorenson EJ, Srinivasen J, Tavee J, Tawil R, Thaisetthawatkul P, Thornton C, Trivedi J, Vernino S, Wang AK, Webb TA, Weiss MD, Windebank AJ, Wolfe GI
2015 Dec
Muscle Nerve
Rituximab-based therapy and long-term control of autoimmune autonomic ganglionopathy.
Gupta A, Harris S, Vernino S, Naina HV 2015 Aug Clin. Auton. Res.
Vernino S
2015 Apr
JAMA Neurol
Muppidi S, Vernino S
2014 Oct
Continuum (Minneap Minn)
5 Peripheral Nervous System Disorders
20
1359-72
Baker SK, Chow BM, Vernino SA
2014 Oct
Neurol Neuroimmunol Neuroinflamm
3
1
e35
Disproportionate pupillary involvement in diabetic autonomic neuropathy.
Yuan D, Spaeth EB, Vernino S, Muppidi S 2014 Nov Clin. Auton. Res.
Low PA, Robertson D, Gilman S, Kaufmann H, Singer W, Biaggioni I, Freeman R, Perlman S, Hauser RA, Cheshire W, Lessig S, Vernino S, Mandrekar J, Dupont WD, Chelimsky T, Galpern WR
2014 Mar
Lancet Neurol
3
13
268-75
Battiste J, Shu F, Vernino S
2014 Jun
JAMA Neurol
6
71
801-2
Shu F, Oberle R, Herndon E, Hatanpaa K, Battiste J, Vernino S
2014 Jan
JAMA Neurol
Li Y, Jammoul A, Mente K, Li J, Shields RW, Vernino S, Rae-Grant A
2014 Dec
Muscle Nerve
Effectiveness of multimodality treatment for autoimmune limbic epilepsy.
Dubey D, Konikkara J, Modur PN, Agostini M, Gupta P, Shu F, Vernino S 2014 Dec Epileptic Disord 4 16 494-9
Muppidi S, Adams-Huet B, Tajzoy E, Scribner M, Blazek P, Spaeth EB, Frohman E, Davis S, Vernino S
2013 Jul
Clin. Auton. Res.
Navalkele DD, Georgescu MM, Burns DK, Greenberg T, Vernino S
2013 Feb
JAMA Neurol
1-5
Haley RW, Charuvastra E, Shell WE, Buhner DM, Marshall WW, Biggs MM, Hopkins SC, Wolfe GI, Vernino S
2013 Feb
JAMA Neurol
2
70
191-200
Ligocki AJ, Rounds WH, Cameron EM, Harp CT, Frohman EM, Courtney AM, Vernino S, Cowell LG, Greenberg B, Monson NL
2013 Apr
Genes Immun.
Slowly progressive ataxia, neuropathy, and oculomotor dysfunction.
Jordan JT, Samuel G, Vernino S, Muppidi S 2012 Oct Arch. Neurol. 10 69 1366-71The spectrum of clinicopathological features in pure autonomic neuropathy.
Koike H, Hashimoto R, Tomita M, Kawagashira Y, Iijima M, Koyano S, Momoo T, Yuasa H, Mitake S, Higashihara M, Kaida K, Yamamoto D, Hisahara S, Shimohama S, Nakae Y, Johkura K, Vernino S, Sobue G 2012 Oct J. Neurol. 10 259 2067-75
Singer MA, Vernino SA, Wolfe GI
2012 May
J. Peripher. Nerv. Syst.
17 Suppl 2
43-9
Graves D, Vernino S
2012 May
Med. Clin. North Am.
3
96
497-523, x
Sudomotor dysfunction in autoimmune autonomic ganglionopathy: a follow-up study.
Kimpinski K, Iodice V, Sandroni P, Fealey RD, Vernino S, Low PA 2012 Jun Clin. Auton. Res. 3 22 131-6
Beh SC, Nations S, Pascual JM, Vernino S
2012 Jul
Arch. Neurol.
7
69
924-7
Clinical reasoning: A 41-year-old comatose man with absent brainstem reflexes.
Beh SC, Vernino S, Warnack WR 2012 Feb Neurology 7 78 e42-5Objective characterization of the relative afferent pupillary defect in MS.
Blazek P, Davis SL, Greenberg BM, Conger A, Conger D, Vernino S, Beh S, Stuve O, Saidha S, Ratchford JN, Green A, Calabresi PA, Balcer LJ, Frohman TC, Frohman EM 2012 Dec J. Neurol. Sci. 1-2 323 193-200
Sharp L, Vernino S
2012 Dec
Muscle Nerve
6
46
841-50
Progressive weakness with respiratory failure in a patient with sarcoidosis.
Chaudhry P, Herndon E, Vernino S, Muppidi S 2012 Apr Arch. Neurol. 4 69 534-7Autoimmune autonomic ganglionopathy with reversible cognitive impairment.
Gibbons CH, Centi J, Vernino S, Freeman R 2012 Apr Arch. Neurol. 4 69 461-6
Vernino S
2012
Handb Clin Neurol
103
215-23
Muppidi S, Gupta PK, Vernino S
2011 Oct
Neurology
16
77
1577-9
Sharp L, Pride L, Mathis D, Raisanen JM, Vernino S
2011 Dec
Arch. Neurol.
12
68
1599-602
Tajzoy E, Mukherjee S, Vernino S
2011 Apr
Arch. Neurol.
4
68
540-1
Isolated neck extensor myopathy: is it responsive to immunotherapy?
Muppidi S, Saperstein DS, Shaibani A, Nations SP, Vernino S, Wolfe GI 2010 Sep J Clin Neuromuscul Dis 1 12 26-9
Winston N, Vernino S
2010 Oct
Curr. Opin. Neurol.
5
23
514-8
Slowly progressive autonomic neuropathy with antiganglionic acetylcholine receptor antibody.
Koike H, Koyano S, Morozumi S, Kawagashira Y, Iijima M, Katsuno M, Hattori N, Vernino S, Sobue G 2010 May J. Neurol. Neurosurg. Psychiatr. 5 81 586-7Progress in the management of paraneoplastic neurological disorders.
Sadeghian H, Vernino S 2010 Jan Ther Adv Neurol Disord 1 3 43-52
Matsui N, Mitsui T, Ohshima Y, Yokoi K, Kunishige M, Yagi F, Vernino S, Matsumoto T, Kaji R
2010
Intern. Med.
1
49
73-7
Kimpinski K, Iodice V, Vernino S, Sandroni P, Low PA
2009 Oct
Auton Neurosci
1-2
150
136-9
Sudomotor dysfunction in autoimmune autonomic ganglionopathy.
Kimpinski K, Iodice V, Sandroni P, Fealey RD, Vernino S, Low PA 2009 Nov Neurology 18 73 1501-6Multifocal paraneoplastic cortical encephalitis associated with myasthenia gravis and thymoma.
Hammoud K, Kandimala G, Warnack W, Vernino S 2009 Nov Arch. Neurol. 11 66 1407-9
Kondo T, Inoue H, Usui T, Mimori T, Tomimoto H, Vernino S, Takahashi R
2009 Mar
Auton Neurosci
1-2
146
33-5
Iodice V, Kimpinski K, Vernino S, Sandroni P, Low PA
2009 Mar
Auton Neurosci
1-2
146
22-5
Autoimmune autonomic ganglionopathy with late-onset encephalopathy.
Baker SK, Morillo C, Vernino S 2009 Mar Auton Neurosci 1-2 146 29-32
Iodice V, Kimpinski K, Vernino S, Sandroni P, Fealey RD, Low PA
2009 Jun
Neurology
23
72
2002-8
Antibody testing as a diagnostic tool in autonomic disorders.
Vernino S 2009 Feb Clin. Auton. Res. 1 19 13-9Direct and consensual murine pupillary reflex metrics: establishing normative values.
Hussain RZ, Hopkins SC, Frohman EM, Eagar TN, Cravens PC, Greenberg BM, Vernino S, Stüve O 2009 Dec Auton Neurosci 2 151 164-7Autoimmune autonomic ganglionopathy: treatment by plasma exchanges and rituximab.
Imrich R, Vernino S, Eldadah BA, Holmes C, Goldstein DS 2009 Aug Clin. Auton. Res. 4 19 259-62
Winston N, Vernino S
2009
Front Neurol Neurosci
26
85-93
Prevalence and mechanism of bladder dysfunction in Guillain-Barre Syndrome.
Sakakibara R, Uchiyama T, Kuwabara S, Mori M, Ito T, Yamamoto T, Awa Y, Yamaguchi C, Yuki N, Vernino S, Kishi M, Shirai K 2009 Neurourol. Urodyn. 5 28 432-7Invited Article: Autonomic ganglia: target and novel therapeutic tool.
Vernino S, Sandroni P, Singer W, Low PA 2008 May Neurology 20 70 1926-32Combined immunomodulatory therapy in autoimmune autonomic ganglionopathy.
Gibbons CH, Vernino SA, Freeman R 2008 Feb Arch. Neurol. 2 65 213-7Antibodies to muscle and ganglionic acetylcholine receptors (AchR) in celiac disease.
Briani C, Doria A, Ruggero S, Toffanin E, Luca M, Albergoni MP, D'Odorico A, Grassivaro F, Lucchetta M, De Lazzari F, Balzani I, Battistin L, Vernino S 2008 Feb Autoimmunity 1 41 100-4Propofol for stiff-person syndrome: learning new tricks from an old dog.
Vernino S, McEvoy K 2008 Apr Neurology 18 70 1584-5
Vernino S
2008
Ann. N. Y. Acad. Sci.
1132
124-8
Peripheral nerve hyperexcitability and the neuromuscular junction.
Vernino S 2008 Handb Clin Neurol 91 433-43
Ogata Y, Charlesworth MC, Higgins L, Keegan BM, Vernino S, Muddiman DC
2007 Oct
Proteomics
20
7
3726-34
Determination of gastric emptying in nonobese diabetic mice.
Choi KM, Zhu J, Stoltz GJ, Vernino S, Camilleri M, Szurszewski JH, Gibbons SJ, Farrugia G 2007 Nov Am. J. Physiol. Gastrointest. Liver Physiol. 5 293 G1039-45Postural orthostatic tachycardia syndrome: the Mayo clinic experience.
Thieben MJ, Sandroni P, Sletten DM, Benrud-Larson LM, Fealey RD, Vernino S, Lennon VA, Shen WK, Low PA 2007 Mar Mayo Clin. Proc. 3 82 308-13EBV-associated lymphoproliferative disorder of CNS associated with the use of mycophenolate mofetil.
O'Neill BP, Vernino S, Dogan A, Giannini C 2007 Jul Neuro-oncology 3 9 364-9
Vernino S, Wolfe GI
2007 Feb
Neurol Clin
1
25
29-46
Dysfunction of the pupillary light reflex in experimental autoimmune autonomic ganglionopathy.
Mukherjee S, Vernino S 2007 Dec Auton Neurosci 1-2 137 19-26
Vernino S
2007 Apr
Neurotherapeutics
2
4
305-14
Vernino S, Geschwind M, Boeve B
2007
13(3)
140-147
Vernino S
2007
4(2)
305-314
Autoimmune Autonomic Ganglionopathy: IgG effects on ganglionic acetylcholine receptor current
Wang Z, Low PA, Jordan J, Freeman R, Gibbons C, Schroeder C, Sandroni P, Vernino S. 2007 68 1917-1921
Vernino S
2006 May
Curr Neurol Neurosci Rep
3
6
193-9
Steroid-responsive encephalopathy associated with autoimmune thyroiditis.
Castillo P, Woodruff B, Caselli R, Vernino S, Lucchinetti C, Swanson J, Noseworthy J, Aksamit A, Carter J, Sirven J, Hunder G, Fatourechi V, Mokri B, Drubach D, Pittock S, Lennon V, Boeve B 2006 Feb Arch. Neurol. 2 63 197-202
Schroeder C, Vernino S, Birkenfeld AL, Tank J, Heusser K, Lipp A, Benter T, Lindschau C, Kettritz R, Luft FC, Jordan J
2005 Oct
N. Engl. J. Med.
15
353
1585-90
L-DOPS therapy for refractory orthostatic hypotension in autoimmune autonomic neuropathy.
Gibbons CH, Vernino SA, Kaufmann H, Freeman R 2005 Oct Neurology 7 65 1104-6
Vernino S
2005 Dec
Neurology
11
65
1688-9
Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil.
Vernino S, Salomao DR, Habermann TM, O'Neill BP 2005 Aug Neurology 4 65 639-41Speech and language findings associated with paraneoplastic cerebellar degeneration.
Paslawski T, Duffy JR, Vernino S 2005 Aug Am J Speech Lang Pathol 3 14 200-7
Josephs KA, Silber MH, Fealey RD, Nippoldt TB, Auger RG, Vernino S
2004 Nov-Dec
J Clin Neurophysiol
6
21
440-5
Autoantibody profiles and neurological correlations of thymoma.
Vernino S, Lennon VA 2004 Nov Clin. Cancer Res. 21 10 7270-5
Kumar N, Crum B, Petersen RC, Vernino SA, Ahlskog JE
2004 May
Arch. Neurol.
5
61
762-6
From parallel to perpendicular: getting "straightened out" with levodopa therapy.
Glynn SM, Pittock SJ, Vernino SA 2004 Jun Mayo Clin. Proc. 6 79 828-9
Sandroni P, Vernino S, Klein CM, Lennon VA, Benrud-Larson L, Sletten D, Low PA
2004 Jan
Arch. Neurol.
1
61
44-8
Immunomodulatory treatment trial for paraneoplastic neurological disorders.
Vernino S, O'Neill BP, Marks RS, O'Fallon JR, Kimmel DW 2004 Jan Neuro-oncology 1 6 55-62Passive transfer of autoimmune autonomic neuropathy to mice.
Vernino S, Ermilov LG, Sha L, Szurszewski JH, Low PA, Lennon VA 2004 Aug J. Neurosci. 32 24 7037-42Potentially reversible autoimmune limbic encephalitis with neuronal potassium channel antibody.
Thieben MJ, Lennon VA, Boeve BF, Aksamit AJ, Keegan M, Vernino S 2004 Apr Neurology 7 62 1177-82Muscle and neuronal autoantibody markers of thymoma: neurological correlations.
Vernino S, Lennon VA 2003 Sep Ann. N. Y. Acad. Sci. 998 359-61
Vernino S, Lennon VA
2003 Sep
Ann. N. Y. Acad. Sci.
998
211-4
Vernino S, Low PA, Lennon VA
2003 Sep
J. Neurophysiol.
3
90
2053-9
Lawn ND, Westmoreland BF, Kiely MJ, Lennon VA, Vernino S
2003 Nov
Mayo Clin. Proc.
11
78
1363-8
Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease.
Lennon VA, Ermilov LG, Szurszewski JH, Vernino S 2003 Mar J. Clin. Invest. 6 111 907-13
Klein CM, Vernino S, Lennon VA, Sandroni P, Fealey RD, Benrud-Larson L, Sletten D, Low PA
2003 Jun
Ann. Neurol.
6
53
752-8
Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K+ channel antibodies.
Oh SJ, Alapati A, Claussen GC, Vernino S 2003 Jun Muscle Nerve 6 27 757-60
Low PA, Vernino S, Suarez G
2003 Jun
Muscle Nerve
6
27
646-61
Myasthenia Gravis, Thymoma, and Intestinal Pseudo-Obstruction: A Case Report and Review.
Rakocevic G, Barohn R, McVey AL, Damjanov I, Morte PD, Vernino S, Lennon V 2003 Dec J Clin Neuromuscul Dis 2 5 93-95Cause-specific mortality after first cerebral infarction: a population-based study.
Vernino S, Brown RD, Sejvar JJ, Sicks JD, Petty GW, O'Fallon WM 2003 Aug Stroke 8 34 1828-32Paraneoplastic neurological autoimmunity associated with ANNA-1 autoantibody and thymoma.
Vernino S, Eggenberger ER, Rogers LR, Lennon VA 2002 Sep Neurology 6 59 929-32
Vernino S, Lennon VA
2002 Nov
Muscle Nerve
5
26
702-7
Paraneoplastic chorea associated with CRMP-5 neuronal antibody and lung carcinoma.
Vernino S, Tuite P, Adler CH, Meschia JF, Boeve BF, Boasberg P, Parisi JE, Lennon VA 2002 May Ann. Neurol. 5 51 625-30
Goldstein DS, Holmes C, Dendi R, Li ST, Brentzel S, Vernino S
2002 Aug
Clin. Auton. Res.
4
12
281-5
ANNA-3 anti-neuronal nuclear antibody: marker of lung cancer-related autoimmunity.
Chan KH, Vernino S, Lennon VA 2001 Sep Ann. Neurol. 3 50 301-11Persistent facial myokymia associated with K(+) channel antibodies.
Gutmann L, Tellers JG, Vernino S 2001 Nov Neurology 9 57 1707-8
Vernino S, Cheshire WP, Lennon VA
2001 May
Auton Neurosci
3
88
187-92
Paraneoplastic and metastatic neurologic complications of Merkel cell carcinoma.
Eggers SD, Salomao DR, Dinapoli RP, Vernino S 2001 Mar Mayo Clin. Proc. 3 76 327-30New Purkinje cell antibody (PCA-2): marker of lung cancer-related neurological autoimmunity.
Vernino S, Lennon VA 2000 Mar Ann. Neurol. 3 47 297-305Fulminant autoimmune cortical encephalitis associated with thymoma treated with plasma exchange.
Rickman OB, Parisi JE, Yu Z, Lennon VA, Vernino S 2000 Dec Mayo Clin. Proc. 12 75 1321-6Myasthenia, thymoma, presynaptic antibodies, and a continuum of neuromuscular hyperexcitability.
Vernino S, Auger RG, Emslie-Smith AM, Harper CM, Lennon VA 1999 Oct Neurology 6 53 1233-9Coma in fulminant pneumococcal meningitis: new MRI observations.
Vernino S, Wijdicks EF, McGough PF 1998 Oct Neurology 4 51 1200-2
Vernino S, Adamski J, Kryzer TJ, Fealey RD, Lennon VA
1998 Jun
Neurology
6
50
1806-13
Vernino SA, Moder KG
1996 May
Mayo Clin. Proc.
5
71
485-8
Postpartum thrombotic thrombocytopenic purpura complicated by Budd-Chiari syndrome.
Hsu HW, Belfort MA, Vernino S, Moake JL, Moise KJ 1995 May Obstet Gynecol 5 Pt 2 85 839-43
Vernino S, Rogers M, Radcliffe KA, Dani JA
1994 Sep
J. Neurosci.
9
14
5514-24
Functional diversity of neuronal nicotinic acetylcholine receptors.
Patrick J, Séquéla P, Vernino S, Amador M, Luetje C, Dani JA 1993 Prog. Brain Res. 98 113-20Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors.
Vernino S, Amador M, Luetje CW, Patrick J, Dani JA 1992 Jan Neuron 1 8 127-34Contact Us
Steven Vernino, M.D., Ph.D.
Professor of Neurology
Phone: 214-648-8816
Fax: 214-648-9129
Lab: 214-648-9275
Mailing Address
5323 Harry Hines Boulevard
Dallas, Texas 75390-8869
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