Search Labs

O'Donnell Lab investigates mechanisms of tumor initiation, progression, and metastasis using molecular and biochemical studies and animal models.

The focus of the Obata Lab is to study how environmental signals (e.g., microbiota, diet, day/night cycles) shape intestinal neural circuits and immune cell networks. A variety of experimental techniques are used, including state-of-the-art imaging technologies, viral tracing of gut innervation, in vivo and ex vivo physiological assays, gnotobiotic systems and multi-omics technologies. The Obata lab is also interested in elucidating the molecular mechanisms of inter-organ communication, including the Gut-Brain axis.

The Oh lab is committed to elucidating how G protein-coupled Receptor (GPCR) works in regulating metabolism and identifying new avenues for developing therapeutics to treat metabolic syndromes such as type 2 diabetes, insulin resistance.

Olson Lab studies muscle cells as a model for understanding how stem cells adopt specific fates and how programs of cell differentiation and morphogenesis are controlled during development.

Orchard Lab at UT Southwestern Medical Center

The Orth lab is interested in elucidation the activity of virulence factors from pathogenic bacteria so that we can gain novel molecular insight into eukaryotic signaling systems.

The Osborne Lab focuses on how regulation of miRNA and mRNA controls the branching of developing cells, and how disregulation of these pathways contributes to aggressive tumor behavior.

The main research focus of the Otwinowski lab is on developing computational and statistical
methods and protocols for macromolecular structure determination using X-ray crystallography.

Oz Lab combines imaging, interventional radiology, radiotracers (novel and known), and animal models to study physiology and disease pathophysiology.