The focus of the Obata Lab is to study how environmental signals (e.g., microbiota, diet, day/night cycles) shape intestinal neural circuits and immune cell networks. A variety of experimental techniques are used, including state-of-the-art imaging technologies, viral tracing of gut innervation, in vivo and ex vivo physiological assays, gnotobiotic systems and multi-omics technologies. The Obata lab is also interested in elucidating the molecular mechanisms of inter-organ communication, including the Gut-Brain axis.
The Oh lab is committed to elucidating how GPCRs work in regulating metabolism and identifying new avenues for developing therapeutics to treat metabolic syndromes such as type 2 diabetes, insulin resistance.
Dayoung Oh, Ph.D.
G protein-coupled receptortype 2 diabetesobesitymetabolic syndrome