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Core Facilities >

Bagrodia Lab

Our research is focused on (1) identifying low-risk patients that would benefit from minimal treatment or surveillance, and (2) devising methods of sensitization to current therapies.

  • Aditya Bagrodia, M.D.

Bai Lab

Our goal is to employ cryo-EM to determine high resolution structures of important membrane protein complexes involved in cellular signaling, including cellular receptors and ion channels. We also combine structural approaches with functional studies to reveal the structure-function relationships of these membrane proteins.

  • Xiaochen Bai

Bailey Lab

The Bailey lab focuses on developing gene therapies for neurological disorders. We work on monogenetic pediatric disorders, including SLC13A5 epileptic encephalopathy, multiple sulfatase deficiency, Charcot Marie Tooth disease type 4J, giant axonal neuropathy and ECHS1 deficiency.

  • Rachel Bailey, Ph.D.
Gene therapy for neurological disorders
Neuroscience

Ball Lab

The primary role of our lab is to provide services to the research community in the areas of organic and analytical chemistry via the Protein Chemistry Technology Core. 

  • Haydn Ball, Ph.D.

Banaszynski Lab

We study the role of chromatin regulation in cell fate decisions.

  • Laura Banaszynski, Ph.D.

Baum Lab

Our laboratory has characterized many of the transporters responsible for proximal tubule acidification and solute transport

  • Michel Baum, M.D.

Bedimo Lab

Dr. Bedimo studies strategies for optimally managing drug-resistant HIV patients, analyzing metabolic abnormalities in HIV patients, and studying the effects of HCV co-infection. 

  • Roger Bedimo, M.D.
Highly Active Anti-retroviral Therapy HAART

Berglund Lab

We are interested in how CNS signals are transmitted via hormonal or neural mechanisms to modulate specific organs, with a special interest diabetes and obesity.

  • Eric Berglund, Ph.D.

Beutler Lab

We combine classical genetics with modern technology to understand human physiology and search for breakthrough treatments for diseases.

  • Bruce Beutler, M.D.

Bioinformatics Lab

The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.

  • Dr. Chao Xing, Director
bioinformatics statistical genomics statistical genetics genetics biostatistics Human Disease Mapping GWAS sequencing
Biomedical Engineering Genetics, Development and Disease

Biomedical Imaging and Radiation Technology (BIRT) Lab

Our mission is to innovate, develop, and apply biomedical technology to empower cancer research.

  • Ken Kang-Hsin Wang
Biomedical imaging radiation therapy
Biomedical Engineering

Biomolecular NMR Facility

This facility is the home to five high field solution NMR spectrometers ranging from 500 MHz to 800 MHz and a Solid State 600 MHz DNP system, primarily in support of studies of macromolecular structure, function and dynamics.

  • Jose Rizo-Rey
  • Michael Rosen
  • Kendra Frederick
  • Xuelian Luo
  • Hongtao Yu
Molecular Biophysics Neuroscience Molecular Biophysics Molecular Biophysics Molecular Biophysics

Blount Lab

Our research is largely aimed at understanding how an organism detects mechanical force.

Molecular Biophysics Molecular Microbiology

Bowen Lab

The Bowen Lab focuses on the development of hybrid positron emission tomography (PET) (e.g. PET-CT and PET-MR) tools to enable precision imaging for the care and study of oncology, neurology, and cardiology patients.

  • Spencer Bowen, Ph.D.
Biomedical Engineering

Brekken Lab

The Brekken laboratory, located in the Hamon Center for Therapeutic Oncology Research, studies tumor-host interactions with a particular emphasis on extracellular matrix (ECM) and angiogenesis.

  • Rolf A. Brekken, Ph.D.
Tumor microenvironment
Cancer Biology

Brown & Goldstein Lab

Our laboratory discovered a family of transcription factors called sterol regulatory element-binding proteins (SREBPs) that control cholesterol and fatty acid synthesis. 

  • Michael S. Brown, M.D., Joseph L. Goldstein, M.D.

Brugarolas Lab

  • To understand how kidney cancer develops at the molecular level.
  • To translate our findings into new treatments for kidney cancer patients.
  • To train the next generation of physicians and scientists.
  • James Brugarolas, M.D., Ph.D.

Burgess Lab

The Burgess lab uses Nuclear Magnetic Resonance spectroscopy and Mass Spectrometry in conjunction with stable isotope (non-radioactive) tracers to study how metabolic flux is altered by disease, pharmacology, or targeted genetic interventions.

  • Shawn Burgess, Ph.D.
Biomedical Engineering

Burstein Lab

Burstein Laboratory focuses on understanding the regulation of the inflammatory response at a molecular level, and elucidating how these events may participate in human disease.

  • Ezra Burstein, M.D., Ph.D.
Inflammation Endosomal biology
Genetics, Development and Disease Immunology

Busch Lab

The Busch Lab develops optical technologies for non- and minimally-invasive bedside assessment of microvascular blood flow and oxygen saturation, allowing continuous assessment of oxygen metabolism. 

  • Dr. David Busch
translational neuromonitoring
Biomedical Engineering Neuroscience

Buszczak Lab

Buszczak laboratory seeks to gain new insights into the unique biology of germ cells.

  • Michael Buszczak, Ph.D.
Germ cells
Genetics, Development and Disease

Butler Lab

Our lab is working with to develop a gene therapy that would allow increased Ube3a expression in the paternal copy of the gene that causes Angelman syndrome.

  • Ryan Butler, Ph.D.
Neuroscience

Butovich Lab

My research interests include lipidomics, enzymology, drug discovery, and bioanalytical chemistry in the relation to ocular biochemistry, biophysics, and physiology. 

  • Igor A. Butovich, Ph.D.
Biological Chemistry