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Core Facilities >

Abrams Lab

We use genetic systems to deconstruct functions associated with the most commonly mutated genes found in human cancers.

  • John M. Abrams, Ph.D.
Transposons Cancer and Cell Death
Cancer Biology Genetics, Development and Disease

Achilefu Lab

Harnessing the power of light to develop methods to understand, diagnose, & treat diseases. The unique strength of the Achilefu Lab (Optical Radiology Lab, ORL) is the ability to develop complete solutions from conception, implementation, and validation to human clinical care. We aim to change the way medicine is practiced.

  • Samuel Achilefu, Ph.D.
Biomedical Engineering

Acute Liver Failure Study Group

The Acute Liver Failure Study Group (ALFSG) is a clinical research network funded by the National Institutes of Health since 1997, to gather important prospective data and biosamples on this rare condition. 

  • William M. Lee, M.D.
  • Shannan Tujios, M.D.

Advanced Imaging and Informatics for Radiation Therapy (AIRT) Lab

The Advanced Imaging and Informatics for Radiation Therapy (AIRT) Lab's research is focused on the development of novel imaging and beam delivery techniques and new machine learning algorithms to improve the efficacy of radiation therapy.

  • Jing Wang, Ph.D., DABR
  • You Zhang, Ph.D., DABR
Clinical Decision Making treatment outcome prediction medical imaging processing medical imaging analysis
Biomedical Engineering

Agarwal Lab

The focus of Dr. Agarwal's research has been on mechanisms of steroid action with emphases on: 1) structure-activity relationships of ligand-steroid receptor interactions, and 2) steroid metabolism.

  • Anil Agarwal, Ph.D.

Aguilera Lab

Our lab is using various approaches to explore this biology and develop new treatments with a focus on targeting tumor intrinsic factors such as genetic programs like the epithelial to mesenchymal transition that coordinate with infiltrating immune cells in enhance therapeutic resistance and assist distant spread.

  • Todd Aguilera, M.D., Ph.D.
immune microenvironment cancer immunotherapy immunotherapy pancreatic cancer
Cancer Biology Immunology

Akbay Lab

Akbay Lab studies genetic and molecular events that lead to lung-tumor initiation and immune evasion. 

  • Esra Akbay, Ph.D.
Tumor immune escape
Cancer Biology Immunology

Alluri Lab

Our mission is to improve the care of breast cancer patients through cutting-edge translational research at the interface of clinical oncology, cancer biology, molecular genetics, and translational genomics.

  • Prasanna Alluri, M.D., Ph.D.
Breast Cancer
Cancer Biology

Alto Lab

Our goal is to track the signaling dynamics of individual effectors and toxins in living cells, using a combination of fluorescent genetic reporters, microinjection of labeled bacterial proteins, and live cell imaging techniques. 

  • Neal M. Alto, Ph.D.
Cell and Molecular Biology Molecular Microbiology

Ariizumi/Cruz Lab

Our group initially investigated a novel immune checkpoint inhibitor targeting a rare heparan sulfate (rHS) in melanoma treatment. Collaboratively, we explored the potential of a single-domain humanized rHS antibody (1A7 clone) that inhibits DC-HIL function and also angiogenesis and chemokine effects linked to diverse cancer progression signaling pathways. This experience provided insights into rHS-targeting as a promising approach to melanoma therapy.

  • Kiyoshi Ariizumi, Ph.D.
  • Ponciano Cruz, M.D.

Arteaga Lab

The Arteaga laboratory has a longstanding interest in understanding the molecular pathways that drive breast cancer progression and influence response to therapies.

  • Carlos L. Arteaga, M.D.
Cancer Biology

Azab Lab

Multidisciplinary research to beat cancer

  • Abd El Kareem Azab, Ph.D.
biomedical engineering drug delivery Nano-Immuno-Oncology Nanomedicine nanoparticle drugs Drug Discovery cancer biology Tumor microenvironment cancer immunotherapy Endothelial Cell Biology Cell Signaling Targeted cancer therapy Tumor immune escape Translational Research T cells Hypoxia
Biomedical Engineering Cancer Biology

Bai Lab

Our goal is to employ cryo-EM to determine high resolution structures of important membrane protein complexes involved in cellular signaling, including cellular receptors and ion channels. We also combine structural approaches with functional studies to reveal the structure-function relationships of these membrane proteins.

  • Xiaochen Bai, Ph.D.

Bailey Lab

The Bailey lab focuses on developing gene therapies for neurological disorders. We work on monogenetic pediatric disorders, including SLC13A5 epileptic encephalopathy, multiple sulfatase deficiency, Charcot Marie Tooth disease type 4J, giant axonal neuropathy and ECHS1 deficiency.

  • Rachel Bailey, Ph.D.
Gene therapy for neurological disorders
Neuroscience

Banaszynski Lab

We study the role of chromatin regulation in cell fate decisions.

  • Laura Banaszynski, Ph.D.
Genetics, Development and Disease

Baum Lab

Our laboratory has characterized many of the transporters responsible for proximal tubule acidification and solute transport

  • Michel Baum, M.D.

Beckham Lab

The Beckham lab is a dynamic multidisciplinary laboratory that studies viral pathogenesis and neuroimmune responses.

  • J. David Beckham, M.D.

Bedimo Lab

Dr. Bedimo studies strategies for optimally managing drug-resistant HIV patients, analyzing metabolic abnormalities in HIV patients, and studying the effects of HCV co-infection. 

  • Roger Bedimo, M.D.
Highly Active Anti-retroviral Therapy HAART

Beutler Lab

We combine classical genetics with modern technology to understand human physiology and search for breakthrough treatments for diseases.

  • Bruce Beutler, M.D.
Immunology

Bezerra Lab

The Bezerra Lab current studies investigate how developmental defects increase the susceptibility of the biliary epithelium to infectious and toxic insults.

  • Jorge Bezerra, M.D.
Immunology

Bioinformatics Lab

The Bioinformatics Lab provides services to manage and analyze next-generation sequencing data.

  • Chao Xing, Ph.D., Director
bioinformatics statistical genomics statistical genetics genetics biostatistics Human Disease Mapping GWAS sequencing
Biomedical Engineering Genetics, Development and Disease

Biomolecular NMR Facility

This facility is the home to five high field solution NMR spectrometers ranging from 500 MHz to 800 MHz and a Solid State 600 MHz DNP system, primarily in support of studies of macromolecular structure, function and dynamics.

  • Jose Rizo-Rey
  • Michael Rosen
  • Kendra Frederick
  • Xuelian Luo
  • Hongtao Yu
Molecular Biophysics Neuroscience Molecular Biophysics Molecular Biophysics Molecular Biophysics