Search Labs

We study how biomolecular condensates organize gene regulation.

A major focus of our lab is to identify mechanisms of cardiomyocyte cell cycle regulation, and discover ways to reawaken regenerative pathways in the adult mammalian heart. We are also developing several structural, molecular, and physiological tools to interrogate the mechanistic underpinnings of various forms of cardiomyopathy.

Saelices Lab employs crystallography and cryo-EM to study amyloid deposition and design anti-amyloid tools.

The Saha Lab.

Sakano Lab investigates FMRP's influence on auditory brainstem development in Fragile X Syndrome. Using a mouse model, we examine gene expression and its potential link to autism, auditory processing, hyperacusis, and tinnitus.

We seek to understand the processes that control the immune system and how they malfunction in autoimmune diseases of the brain, including multiple sclerosis (MS).

We seek to understand how RNA/protein assemblies control cellular states, and how related pathways are hijacked by diseases of aging.

The Sandstrom Lab works to identify the fundamental molecular mechanisms through which the immune system can recognize pathogens and stress. 

Satterthwaite Lab studies the signals that control B lymphocyte development, activation, and differentiation into antibody-secreting plasma cells, both normally and in autoimmune diseases such as lupus. We hope that by defining these events, we can reveal new approaches to modulate antibody responses therapeutically.

The Saunders Lab aims to advance our understanding of the bacterial domain of life using high throughput genetics to map the molecular interactions that underly cellular physiology.

The Saxena lab's research interests include Icodextin in high peritoneal transporters; Kremezin study in patients with chronic kidney disease; SV40 in focal segmental glomerulosclerosis; molecular studies in lupus nephritis.

The main focus in our laboratory is the identification and physiological characterization of adipocyte-specific gene products and the elucidation of pathways that are an integral part of the complex set of reactions that drive adipogenesis.

The lab investigates the nature and treatment of cognitive deficits commonly seen in schizophrenia and related disorders.

The Schoggins Lab studies innate immunity at the virus-host interface. We are interested in mechanisms of cellular antiviral defense and the role these responses play during viral disease.

What are the causes and consequences of cytoskeletal diversification?

The Seemann Lab studies the molecular mechanisms governing the function and inheritance of the mammalian Golgi apparatus.

We aim to characterize the ways in which reward systems vary from individual to individual and understand how this variation determines propensity for depression and addiction-like behavior.

Nutrition and exercise intervention to reduce cardiovascular risk factors; weight loss and maintenance in bariatric surgery patients; role of nutrition and exercise in cardiovascular risk factors; influence of the eating environment on energy intake.

Our lab researches Cerebellar Dysfunction, Brainstem Dysfunction, High-Throughput Screen, and Human Studies.

The Shamoradian lab focuses on deciphering the structure and native cellular context of brain disease-causing proteins using cryo-electron microscopy and tomography. 

The Sharma lab is interested in investigating intermediary metabolism utilizing carbon-13 stable isotope tracers in conjunction with magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI), and mass spectrometry (MS).

The overall goal of our laboratory is to discover the processes in endothelial cells that govern cardiovascular and metabolic health and disease. 

Shay Lab is interested in the relationships between aging and cancer and have focused on the role of the telomeres and telomerase in these processes.

The ultimate aim of the Shiloh Lab is to contribute to the development of vaccines and treatments for Mycobacterium tuberculosis (Mtb).