Cutting-edge microscopy to understand the macromolecular context of neurodegeneration

Imaging at nanoscales

The key to our success is collaboration

A researcher points to an image on a computer screen while another looks on.

Meet the PI

Sarah Shahmoradian

Sarah Shahmoradian, Ph.D.

I was born and raised in Richmond, Virginia. I earned my B.S. in biology with a research focus in neurobiology at James Madison University, and my Ph.D. in molecular physiology and biophysics from the Baylor College of Medicine.

My lab focuses on deciphering the structures of macromolecular assemblies and associated cellular components relevant to neurodegenerative disease using integrative multi-modal microscopy approaches, with an emphasis on correlative light and electron microscopy (CLEM) and cryo-electron tomography (cryo-ET). Our studies encompass cells, animal models, and human patients. We also develop and apply new technologies to push the boundaries of these techniques.