Publications

Title

Cited

Year

Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes

SH Shahmoradian, AJ Lewis, C Genoud, J Hench, TE Moors, PP Navarro, ...

Nature Neuroscience 22 (7), 1099-1109

1056

2019

TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

X Zhao, XQ Chen, E Han, Y Hu, P Paik, Z Ding, J Overman, AL Lau, ...

PNAS

110

2016

TRiC’s tricks inhibit huntingtin aggregation

SH Shahmoradian, JG Galaz-Montoya, MF Schmid, Y Cong, B Ma, ...

Elife 2, e00710

101

2013

Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract.

K Shen, B Calamini, J Fauerbach, B Ma, SH Shahmoradian, LIL Serrano, ...

eLife 5, https://elifesciences.org/content/5/e180

85

2016

Three-Dimensional Imaging of Biological Tissue by Cryo X-Ray Ptychography

SH Shahmoradian, EHR Tsai, A Diaz, M Guizar-Sicairos, J Raabe, ...

Scientific Reports 7 (doi:10.1038/s41598-017-05587-4)

73

2017

OMNY PIN—A versatile sample holder for tomographic measurements at room and cryogenic temperatures

M Holler, J Raabe, R Wepf, SH Shahmoradian, A Diaz, B Sarafimov, ...

Review of Scientific Instruments 88 (11)

69

2017

Breakthroughs in medicine and bioimaging with up-conversion nanoparticles

I Rostami, AH Rezvani, Z Hu, SH Shahmoradian

International Journal of Nanomedicine

63

2019

Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation

JA Fauerbach, DA Yushchenko, SH Shahmoradian, W Chiu, TM Jovin, ...

Biophysical journal 102 (5), 1127-1136

49

2012

Imaging of post-mortem human brain tissue using electron and X-ray microscopy

AJ Lewis, C Genoud, M Pont, WDJ van de Berg, S Frank, H Stahlberg, ...

Current opinion in structural biology 58, 138-148

38

2019

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles

PP Navarro, C Genoud, D Castaño-Díez, A Graff-Meyer, AJ Lewis, ...

Scientific reports 8 (1), 18046

38

2018

Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240

P Kunach, J Vaquer-Alicea, MS Smith, J Monistrol, R Hopewell, L Moquin, ...

Nature communications 15 (1), 8497

37

2024

Cryo-electron tomography provides topological insights into mutant huntingtin exon 1 and polyQ aggregates

JG Galaz-Montoya, SH Shahmoradian, K Shen, J Frydman, W Chiu

Communications Biology 4 (1), 849

32

2021

Patterning of multiple layered projections to the auditory midbrain prior to experience

RL Fathke, ML Gabriele

Hearing research 249 (1-2), 36-43

31

2009

A lathe system for micrometre-sized cylindrical sample preparation at room and cryogenic temperatures

M Holler, J Ihli, EHR Tsai, F Nudelman, M Verezhak, WD van de Berg, ...

Synchrotron Radiation 27 (2), 472-476

23

2020

Preparation of Primary Neurons for Visualizing Neurites in a Frozen-hydrated State Using Cryo-Electron Tomography

SH Shahmoradian, MR Galiano, C Wu, S Chen, MN Rasband, ...

Journal of Visualized Experiments

23

2014

Early segregation of layered projections from the lateral superior olivary nucleus to the central nucleus of the inferior colliculus in the neonatal cat

ML Gabriele, SH Shahmoradian, CC French, CK Henkel, JG McHaffie

Brain research 1173, 66-77

18

2007

Alterations in sub-axonal architecture between normal aging and Parkinson’s diseased human brains using label-free cryogenic x-ray nanotomography

HT Tran, EHR Tsai, AJ Lewis, T Moors, J Bol, I Rostami, A Diaz, AJ Jonker, ...

Frontiers in neuroscience 14, 570019

13

2020

TorsinA is essential for neuronal nuclear pore complex localization and maturation

S Kim, S Phan, HT Tran, TR Shaw, SH Shahmoradian, MH Ellisman, ...

Nature cell biology 26 (9), 1482-1495

8

2024

Micrometer-resolution reconstruction and analysis of whole mouse brain vasculature by synchrotron-based phase-contrast tomographic microscopy

A Miettinen, AG Zippo, A Patera, A Bonnin, SH Shahmoradian, ...

bioRxiv, 2021.03. 16.435616

8

2021

Functional classification of tauopathy strains reveals the role of protofilament core residues

J Vaquer-Alicea, VA Manon, V Bommareddy, P Kunach, A Gupta, ...

Science Advances 11 (4), eadp5978

7

2025

Docking for molecules that bind in a symmetric stack with SymDOCK

MS Smith, IS Knight, RC Kormos, JG Pepe, P Kunach, MI Diamond, ...

Journal of Chemical Information and Modeling 64 (2), 425-434

7

2024

Correlative light and electron microscopy for human brain and other biological models

N Shafiei, D Stӓhli, D Burger, M Di Fabrizio, L van den Heuvel, J Daraspe, ...

Nature protocols, 1-30

6

2025

Functional classification of tauopathy strains reveals the role of protofilament core residues

J Vaquer-Alicea, VA Manon, V Bommareddy, P Kunach, A Gupta, ...

bioRxiv, 2024.09. 30.615521

2

2024

A compartmentalized neuronal cell-culture platform compatible with cryo-fixation by high-pressure freezing for ultrastructural imaging

HT Tran, MS Lucas, T Ishikawa, SH Shahmoradian, C Padeste

Frontiers in neuroscience 15, 726763

2

2021

Banded ephrin-B3 expression patterns in the neonatal rat inferior colliculus

SH Shahmoradian, RL James, NS Simpson, ML Gabriele

Soc for Neurosci Abstr 35, 942.2

2

2005

Topological Insights into Mutant Huntingtin Exon 1 and PolyQ Aggregates by Cryo-Electron Tomography

JG Galaz-Montoya, SH Shahmoradian, K Shen, J Frydman, W Chiu

bioRxiv, 2020.12. 08.417048

1

2020

Elucidating Tau Fibril Formation using Correlative Cryo-CLEM in situ

S Shahmoradian

Structural Dynamics 12 (2_Supplement), A351-A351

 

2025

Multi-immersion Oblique Plane Microscope (miOPM): A reconfigurable platform for high-resolution Light-Sheet Fluorescence Microscopy.

B Chen, A Millett-Sikking, S Galecki, S Daetwyler, J Jiou, J Monistrol, ...

bioRxiv, 2025.10. 04.680473

 

2025

Abstract 2445 Elucidating Tau Fibril Formation using Correlative Cryo-CLEM in situ

S Shahmoradian, J Monistrol, HT Tran, V Perez, J Jiou, J Vaquer-Alicea, ...

Journal of Biological Chemistry 300 (3)

 

2024

Docking for molecules that bind in a symmetric stack to Alzheimer’s disease tau fibrils with SymDOCK

MS Smith, P Kunach, IS Knight, R Kormos, JG Pepe, I Glenn, JJ Irwin, ...

Biophysical Journal 123 (3), 298a

 

2024

Cryo-EM structure determination of sub nanomolar affinity PET ligand, MK-6240, bound to Alzheimer’s Disease Paired Helical Filament

P Kunach, J Vaquer-Alicea, J Monistrol, J Therriault, C Tissot, R Hopewell, ...

Alzheimer's Association International Conference

 

2023

Structural Characterizations of Aggregating Proteins Relevant to Neurodegenerative Diseases

SH Shahmoradian

Baylor College of Medicine. Department of Molecular Physiology and Biophysics.

 

2013

In vivo blood-brain barrier permeability assessment with Mn-enhanced MRI (MEMRI).

SH Shahmoradian, Y Sun, RG Pautler

Proc. Intl. Soc. Mag. Reson. Med 14, 2337

 

2006