Research
The Bann Laboratory focuses on discovering novel mechanistic targets to treat heart failure. We aim to identify regulators of cardiac cell fate reprogramming and regeneration as a molecular strategy to repair and heal the heart following injury.
Dr. Glynnis Garry Bann: I'm Glynnis Garry Bann, and I'm a cardiologist and physician-scientist in the departments of internal medicine and molecular biology. In our laboratory, we work on discovering therapies for heart failure, which is the leading cause of death, worldwide. The heart is one of the least regenerative organs in the human body. After you have a heart attack, millions of heart cells die and they don't come back. Scar tissue forms in its place, which then causes heart failure. So in our laboratory, we study a process called cardiac reprogramming, which aims to rewire or reprogram the DNA in these scar cells and convince them to become contractile heart cells. This process aims to remuscularize and improve the function of the heart following heart attack. One of the things that really drew me to UT Southwestern is the tremendous support and value for physician scientists, but also its incredible vision. The vision here at UT Southwestern, I think is really contagious, and it's something that draws in the best investigators in the world and really impacts, not only our culture, but the way that we think about and do science, and I couldn't imagine a better place to be starting my own laboratory.
Meet the PI

Glynnis Garry Bann, M.D.
Assistant Professor
Internal Medicine I Molecular Biology
Hamon Center for Regenerative Science and Medicine
Dr. Glynnis Garry Bann is a cardiovascular physician-scientist interested in identifying novel therapies for heart failure. Beyond treating patients with cardiovascular disease, she is passionate about understanding the fundamental mechanisms that dictate cell fate decisions and dissecting the epigenetic and transcriptional cues that regulate cardiac cell fate reprogramming, development, and regeneration.