Aguilera Lab | UT Southwestern, Dallas, Texas

The Aguilera Lab aims to study the biology of the immune microenvironment from animal models to our patients in the clinic.

Our lab is using various approaches to explore this biology and develop new treatments with a focus on targeting tumor intrinsic factors such as genetic programs like the epithelial to mesenchymal transition that coordinate with infiltrating immune cells to enhance therapeutic resistance and assist distant spread.

View Our Research

This painting by Stanley Chiu was inspired by his fight with pancreatic cancer.

We are inspired:
by those with cancer who have entered and exited our lives.

Slide of tumor microenvironment

Immune privilege:
in the tumor microenvironment.

Immune microenvironment imaging

Radiation:
how it modulates the immune microenvironment.

Bio-engineering diagram

Engineering:
develop approaches to target cancer and the immune system.

This painting by Stanley Chiu was inspired by his fight with pancreatic cancer.

Slide of tumor microenvironment

Immune microenvironment imaging

Bio-engineering diagram

INSPIRE-seq: a new way to identify targets and develop drugs

Get Involved

Meet the Team

Get to know our Principal Investigator and team of researchers.

See Lab Members

Aguilera team poses on stairs

Collaborate

Interested in our research? Get in touch to learn more or find out ways to collaborate.

The Aguilera team playfully looking up at camera

Join Our Lab

If you're interested in joining our team, please reach out to learn more about open positions.

Explore Opportunities

Aguilera Lab team posing in office