Busch Lab

Meet the Principal Investigator

Dr. David Busch

Dr. David Busch

Dr. Busch is an assistant professor in the Department of Anesthesiology and Pain Management, with a secondary appointment in Neurology and Neurotherapeutics. His work translates tools and techniques from the physical sciences to solve pressing clinical problems, primarily in monitoring the brain and spinal cord, as well as the efficacy of cancer therapy. Much of his research utilizes diffuse optical spectroscopies, minimally and non-invasive quantitative tools which enable continuous, long-term measurements. He has frequently utilized these optical tools in combination with other imaging/monitoring modalities. Dr. Busch’s work has been funded by the Fulbright Commission, the Institute of International Education Whitaker Fellowship, the Thrasher Research Foundation, and the Hartwell Foundation. 

Research

Our lab develops optical technologies for non- and minimally-invasive bedside assessment of microvascular blood flow and oxygen saturation, allowing continuous assessment of oxygen metabolism. We utilize diffuse optical and correlation spectroscopies to provide continuous, quantitative brain and spinal cord health during critical care.

Current projects:

Monitoring cerebral hemodynamics during pediatric extracorporeal circulatory support

  • Collaborators: Lakshmi Raman M.D. (Children’s Health Center) Fenghua Tian Ph. D. (UT Arlington)
  • Funding: Hartwell Foundation

Developing tools for spatially-resolved continuous intraoperative measurement of spinal cord blood flow

  • Collaborators: Thomas Floyd M.D., Wei Lin Ph. D. (Stony Brook University), Arjun Yodh Ph. D. (University of Pennsylvania)
  • Funding: NIH-NINDS (U01-NS095761 Floyd PI)

All Publications

Contact Us

Dept. of Anesthesiology and Pain Management

5323 Harry Hines Blvd
Dallas, Texas 75390
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Join Our Lab

Non- and minimally-invasive diffuse optical tissue monitoring

A postdoctoral position is available in the laboratory of David R. Busch, Ph. D. in the Departments of Anesthesiology and Pain Management & Neurology and Neurotherapeutics at UT Southwestern Medical Center. This laboratory, new to UTSW, focuses on the development and translation of diffuse optical and correlation spectroscopic instrumentation to monitor the central nervous system.
Candidates must hold a Ph.D. in physics, biomedical engineering, bioengineering, or a similar field. A solid record of publication is required to demonstrate writing and technical expertise. Candidates with experience in the development of fiber optic probes, diffuse optics (DCS/DOT/DOS), tissue optics, and clinical translation are preferred. Previous work in an operating theater or intensive care unit is helpful.

The fellow will be focused on the translation of diffuse optics into the surgical and critical care setting. This work is performed in close collaboration with enthusiastic clinical collaborators. Current projects include non-invasive monitoring of cerebral hemodynamics during extracorporeal membrane oxygenation (Prof. Lakshmi Raman, Children’s Medical Center, PI: Busch, Hartwell Foundation) and minimally invasive monitoring of the spinal cord in animal models (Prof. Thomas Floyd, UTSW, PI: Floyd, NIH U01). The fellow will be expected and encouraged to develop new lines of research, collecting pilot data for their future independent research careers, within the general themes of the lab.
This lab and our collaborators are committed to the professional development of the members, making this position a valuable preparation for those interested in academic, industrial, or entrepreneurial careers. The position has no mandatory teaching or administrative duties.
The initial appointment is for 12 months with the possibility of renewal. Compensation will be commensurate with experience and includes competitive benefits.

Interested individuals should send a CV, statement of interests, expected date of availability, and a list of three references to:

David R. Busch, Ph. D.

UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9068