INTERNAL MEDICINE RESEARCH

Miguel Vazquez Lab

Research Interests

Chronic kidney disease is associated with increased morbidity and mortality. Diabetes and hypertension are the most common causes of chronic kidney disease. Our team at UT Southwestern is conducting the study Improving Chronic Disease Management with Pieces (IDC-Pieces) in patients with coexistent chronic kidney disease, diabetes, and hypertension. This is a large multicenter pragmatic clinical trial supported by the Healthcare Systems Collaboratory of the National Institutes of Health. Our study is a collaboration with colleagues from the Parkland Center for Clinical Innovations and four large healthcare systems (Parkland Health and Hospital Systems, Texas Health Resources, VA of North Texas Health Care System, and ProHealth of Connecticut). ICD Pieces will test if a collaborative model of care incorporating a novel technology platform and practice facilitators will improve outcomes for patients with chronic kidney disease, diabetes, and hypertension.

Featured Publications

Pragmatic Clinical Trials in CKD: Opportunities and Challenges.
de Boer IH, Kovesdy CP, Navaneethan SD, Peralta CA, Tuot DS, Vazquez MA, Crews DC J.
Am. Soc. Nephrol. 2016 Jun

Acute Rejection Rates and Graft Outcomes According to Induction Regimen among Recipients of Kidneys from Deceased Donors Treated with Tacrolimus and Mycophenolate.
Tanriover B, Jaikaransingh V, MacConmara MP, Parekh JR, Levea SL, Ariyamuthu VK, Zhang S, Gao A, Ayvaci MU, Sandikci B, Rajora N, Ahmed V, Lu CY, Mohan S, Vazquez MA
Clin J Am Soc Nephrol 2016 Jun

Vascular Function at Baseline in the Hemodialysis Fistula Maturation Study.
Dember LM, Imrey PB, Duess MA, Hamburg NM, Larive B, Radeva M, Himmelfarb J, Kraiss LW, Kusek JW, Roy-Chaudhury P, Terry CM, Vazquez MA, Vongpatanasin W, Beck GJ, Vita JA
J Am Heart Assoc 2016 5 7

Oversight on the borderline: Quality improvement and pragmatic research.
Finkelstein JA, Brickman AL, Capron A, Ford DE, Gombosev A, Greene SM, Iafrate RP, Kolaczkowski L, Pallin SC, Pletcher MJ, Staman KL, Vazquez MA, Sugarman
J Clin Trials 2015 Sep

Induction Therapies in Live Donor Kidney Transplantation on Tacrolimus and Mycophenolate With or Without Steroid Maintenance.
Tanriover B, Zhang S, MacConmara M, Gao A, Sandikci B, Ayvaci MU, Mete M, Tsapepas D, Rajora N, Mohan P, Lakhia R, Lu CY, Vazquez M
Clin J Am Soc Nephrol 2015 Jun 10 6 1041-9

Effect of fish oil supplementation on graft patency and cardiovascular events among patients with new synthetic arteriovenous hemodialysis grafts: a randomized controlled trial.
Lok CE, Moist L, Hemmelgarn BR, Tonelli M, Vazquez MA, Dorval M, Oliver M, Donnelly S, Allon M, Stanley K
JAMA 2012 May 307 17 1809-16

Effect of dipyridamole plus aspirin on hemodialysis graft patency.
Dixon BS, Beck GJ, Vazquez MA, Greenberg A, Delmez JA, Allon M, Dember LM, Himmelfarb J, Gassman JJ, Greene T, Radeva MK, Davidson IJ, Ikizler TA, Braden GL, Fenves AZ, Kaufman JS, Cotton JR, Martin KJ, McNeil JW, Rahman A, Lawson JH, Whiting JF, Hu B, Meyers CM, Kusek JW, Feldman HI
N. Engl. J. Med. 2009 May 360 21 2191-201

Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial.
Dember LM, Beck GJ, Allon M, Delmez JA, Dixon BS, Greenberg A, Himmelfarb J, Vazquez MA, Gassman JJ, Greene T, Radeva MK, Braden GL, Ikizler TA, Rocco MV, Davidson IJ, Kaufman JS, Meyers CM, Kusek JW, Feldman HI
JAMA 2008 May 299 18 2164-71

The evaluation of renal transplantation candidates: clinical practice guidelines.
Kasiske BL, Cangro CB, Hariharan S, Hricik DE, Kerman RH, Roth D, Rush DN, Vazquez MA, Weir MR
Am. J. Transplant. 2001 1 Suppl 2 3-95

Recommendations for the outpatient surveillance of renal transplant recipients. American Society of Transplantation.
Kasiske BL, Vazquez MA, Harmon WE, Brown RS, Danovitch GM, Gaston RS, Roth D, Scandling JD, Singer GG J.
Am. Soc. Nephrol. 2000 Oct 11 Suppl 15 S1-86

Contact Vazquez Lab

Kidney Research
5323 Harry Hines Blvd.
Dallas, TX 75390
Phone: 214-648-8884
Fax: 214-648-2071