Liu (Xin) Lab

Our Research

Xin Liu Lab is interested in understanding the regulation of transcription and chromatin dynamics underlying many fundamental biological processes including differentiation, development, and oncogenesis.

The current research of the laboratory is focused on elucidating the molecular and biophysical basis of chromatin organization, including chromatin looping and heterochromatin formation during gene activation and silencing, with a combined approach of structural biology, biochemistry, and chemical biology.

Meet the Principal Investigator

Xin Liu, Ph.D.

Xin Liu, Ph.D.

Dr. Liu is Assistant Professor in the Cecil H. and Ida Green Center for Reproductive Biology Sciences of the Department of Obstetrics and Gynecology. He is also Assistant Professor in the Department of Biophysics and W.W. Caruth, Jr. Scholar in Biomedical Research.

Dr. Liu did his graduate research in the laboratory of Dr. Ronen Marmorstein at the Wistar Institute and the University of Pennsylvania, where he carried out structural and functional studies on the retinoblastoma and p300/CBP tumor suppressor proteins and their regulation by viral oncoproteins. He received his Ph.D. in Chemistry in 2007. Dr. Liu was a Jane Coffin Childs postdoctoral fellow in the laboratory of Dr. Roger Kornberg at Stanford University from 2008 to 2011, where he studied the molecular basis of eukaryotic transcription.

Meet the Lab Members

Matthew Bratkowsk

Postdoctoral Researcher

Matthew Bratkowsk

Liangying Jiao

Lab Member

Liangying Jiao

Banupriya Mukundan

Postdoctoral Researcher

Banupriya Mukundan

Chengkun Wang

Postdoctoral Researcher

Chengkun Wang

Simming Chen

Postdoctoral Researcher

Simming Chen

Xin Yang

Lab Member

Xin Yang

Murtada Shubbar

Lab Tech

Murtada Shubbar

Qi Zhang

Undergraduate Student

Qi Zhang

Publications

All Publications

Contact Us

Xin Liu, Ph.D.
Assistant Professor
Department of Pharmacology

Phone: 214-648-2493
Lab Phone: 214-648-4516

Email

Mailing Address
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9041