The Aging Brain Stress Response Signaling Lipid Metabolism Traumatic Brain Injury

Research in the Douglas Lab seeks to understand how stress response pathways alter cell physiology, and ultimately influence the aging process and human disease. We can harness latent stress response pathways and apply their protective properties to a multitude of disease models.

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News Updates

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The Douglas Lab Celebrates 10 Years

Date: November 7, 2025

The Douglas Lab marked its 10th anniversary in scientific research by hosting its 5th DALLAS (Douglas AnnuaL Lipid Aging & Stress) Symposium in Texas, bringing together researchers, collaborators, and respected peers in the field of worm research to celebrate a decade of innovation. The event highlighted the lab’s key scientific achievements, showcased ongoing breakthroughs, and fostered meaningful discussions on the future of their research fields. The symposium served as both a milestone celebration and a forward-looking platform for new ideas and collaborations.

 

 

Surveillance pathway tells cells when they run low on lipids

Date: May 18, 2022

Source: UT Southwestern Medical Center

Summary: Researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation. The findings might someday lead to new ways to combat metabolic disorders and a variety of other health conditions.

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Meet the Principal Investigator

Peter Douglas, PhD

Peter Douglas, PhD

Dr. Douglas is a faculty member of the Hamon Center for Regenerative Science and Medicine (CRSM) in the Department of Molecular Biology and an integral part of the Genetics, Development and Disease (GDD), and Neuroscience Graduate Programs at UT Southwestern.

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