Protein aggregation and disease


We are studying neurodegeneration from the standpoint of prion biology and protein aggregation. All major neurodegenerative diseases are relentlessly progressive, and virtually all are linked to the accumulation of protein amyloids.

Meet the PI

Marc Diamond

Marc Diamond, M.D.

Dr. Diamond has made original discoveries linking common disorders such as Alzheimer’s disease to rare infectious prion disorders. This has transformed the scientific community’s understanding of why neurogenerative diseases progress, and how different diseases arise. His lab has discovered that abnormal assemblies of the tau protein move between cells and serve as templates for their own replication. Dr. Diamond’s ideas have formed the basis of new therapeutic approaches for Alzheimer’s and related disorders. He holds multiple patents and is the inventor of a monoclonal antibody that is currently in clinical trials.

Faculty Profile