People

Title

Professor, Internal Medicine, McDermott Center for Human Growth and Development

Education

1975 B.S. in Biochemistry, Beijing University, Beijing, China

1985 Ph.D. in Biochemistry, Cornell University, Ithaca, New York

Research Experience and Professional Appointments

1975-1976 Undergraduate Research, Peking University, Beijing, China

1976-1978 Research Assistant, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

1978-1980 Graduate Research Assistant, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Advisor: Dr. Fu-yu Yang

1980-1985 Graduate Research Assistant, Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, New York, Advisor: Dr. Efraim Racker

1985-1987 Research Assistant Professor, Department of Internal Medicine, UT Southwestern Medical Center at Dallas

1987-1990 Assistant Professor of Physiology, Department of Physiology, UT Southwestern Medical Center at Dallas

1987-present Member of Graduate Faculty, Graduate Program of Biochemistry, UT Southwestern Graduate School of Biomedical Sciences

1990-1998 Associate Professor of Internal Medicine, Division of Molecular Transport, Department of Internal Medicine, UT Southwestern Medical Center at Dallas

1998-Present Professor of Internal Medicine, Division of Molecular Transport, Department of Internal Medicine, UT Southwestern Medical Center at Dallas

2001-present Professor of Internal Medicine, McDermott Center for Human Growth and Development, UT Southwestern Medical Center at Dallas

Invited Lectures

1. Endomembrane H⁺-translocation ATPase from clathrin-coated vesicles.  American Society of Nephrology, New Orleans, LA , 1987.
2. The third-type H⁺-translocating ATPase, Institute of Biophysics, Academia Sinica, Beijing, China, 1988
3. Structure and function of clathrin-coated vesicle V-ATPase, University of Texas at Dallas, Dallas, TX, 1993.
4. Structure and function of bovine brain V-ATPase, Shanghai Medical University, Shanghai, China, 1998.
5. Clathrin-coated vesicle H⁺-ATPase, issue of structure and function, National Laboratory of BioMacromolecules, Academia Sinica, Beijing, China, 1999
6. Inhibition of bovine brain V-ATPase by salicylihalamide, Bristol-Myers Squibb Company, Princeton, NJ, 2002.
7. Structure and function of V-type H⁺-ATPase,  the Institute of Biophysics, Academia, Beijing, China, 2002.
8. How lipids are transported cross membranes: Examples of aminophospholipid translocase and ABC transporters, National Institute of Biological Sciences, Beijing, China, 2005.
9. ATP-driven ion pumps and lipid transporters, The Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, 2005.
10. Purification and Reconstitution of Sterol Transfer by Native Mouse ABCG5 and ABCG8, Conference of Cellular Lipid Transport – Connecting Fundamental Membrane Assembly Processes to Human Disease, organized by American Society for Biochemistry and Molecular Biology, in Canmore, Canada, October 23, 2008