Publications

Immune landscape in liver of neonatal mice with phlebotomy-induced anemia

Ramatchandirin B, Wang W, Balamurugan MA, Alnahhas Y, Desiraju S, Subrramanya A, George Raj J, Lawal ZD, Ferris M, Tseng G, Konnikova L, MohanKumar K 2025 Pediatric Research

Platelet specific knockout of integrin beta-3 (β3) reduces severity of necrotizing enterocolitis in murine neonates

Balamurugan MA, Ramatchandirin B, Desiraju S, Subrramanya A, George Raj J, Ferris MM, Lawal ZD, Olaloye OO, Konnikova L, MohanKumar K 2025 Frontiers in Pediatrics 13

Red blood cell transfusion exacerbates phlebotomy-induced anemia-associated neuroinflammation in murine neonates

George Raj J, Shrestha P, Ramatchandirin B, Balamurugan MA, Desiraju S, Subrramanya A, Fine S, Peeples E, Krishnan MK 2025 Transfusion

Stored RBC transfusions leads to the systemic inflammatory response syndrome in anemic murine neonates

Ramatchandirin B, Balamurugan MA, Desiraju S, Chung Y, Wojczyk BS, MohanKumar K 2024 Nov Inflammation Research 73 1859-1873

A Detailed Protocol for the Induction of Anemia and RBC Transfusion–associated Necrotizing Enterocolitis in Neonatal Mice

Ramatchandirin B, Balamurugan MA, Desiraju S, Chung Y, MohanKumar K 2024 May Bio-protocol 14

Hematological changes in neonatal mice with phlebotomy-induced anemia

Chung Y, Desiraju S, Namachivayam K, Guzman P, He L, MohanKumar K 2022 Dec Pediatric Research 92 1575-1579

The P300 acetyltransferase inhibitor C646 promotes membrane translocation of insulin receptor protein substrate and interaction with the insulin receptor

Peng J, Ramatchandirin B, Wang Y, Pearah A, Namachivayam K, Wolf RM, Steele K, MohanKumar K, Yu L, Guo S, White MF, Maheshwari A, He L 2022 Mar Journal of Biological Chemistry 298

Mutation-Induced Long-Range Allosteric Interactions in the Spike Protein Determine the Infectivity of SARS-CoV-2 Emerging Variants

Das JK, Thakuri B, Mohankumar K, Roy S, Sljoka A, Sun GQ, Chakraborty A 2021 Nov ACS Omega 6 31305-31320

Targeted inhibition of thrombin attenuates murine neonatal necrotizing enterocolitis

Namachivayam K, MohanKumar K, Shores DR, Jain SK, Fundora J, Everett AD, He L, Pan H, Wickline SA, Maheshwari A 2020 May Proceedings of the National Academy of Sciences of the United States of America 117 10958-10969

Lyophilization of human amniotic fluid is feasible without affecting biological activity

Coon JI, Jain S, Sepuru KM, Chung Y, Mohankumar K, Rajarathnam K, Jain SK 2020 Apr Pediatric Research 87 847-852

Severe neonatal anemia increases intestinal permeability by disrupting epithelial adherens junctions

MohanKumar K, Namachivayam K, Sivakumar N, Alves NG, Sidhaye V, Das JK, Chung Y, Breslin JW, Maheshwari A 2020 American Journal of Physiology - Gastrointestinal and Liver Physiology 318 G705-G716

A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions

MohanKumar K, Namachivayam K, Song T, Jake Cha B, Slate A, Hendrickson JE, Pan H, Wickline SA, Oh JY, Patel RP, He L, Torres BA, Maheshwari A 2019 Dec Nature communications 10

Neonatal mice with necrotizing enterocolitis-like injury develop thrombocytopenia despite increased megakaryopoiesis

Namachivayam K, Mohankumar K, Garg L, Torres BA, Maheshwari A 2017 May Pediatric Research 81 817-824

Cytokines and growth factors in the developing intestine and during necrotizing enterocolitis

MohanKumar K, Namachivayam K, Ho TT, Torres BA, Ohls RK, Maheshwari A 2017 Feb Seminars in Perinatology 41 52-60

Trinitrobenzene sulfonic acid-induced intestinal injury in neonatal mice activates transcriptional networks similar to those seen in human necrotizing enterocolitis

Kumar KM, Namachivayam K, Cheng F, Jiang RH, Flores-Torres J, Torres BA, Maheshwari A 2017 Jan Pediatric Research 81 99-112

Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis

MohanKumar K, Namachivayam K, Chapalamadugu KC, Garzon SA, Premkumar MH, Tipparaju SM, Maheshwari A 2016 Jun Pediatric Research 79 951-961

Transforming growth factor–β2 is sequestered in preterm human milk by chondroitin sulfate proteoglycans

Namachivayam K, Coffing HP, Sankaranarayanan NV, Jin Y, Mohankumar K, Frost BL, Blanco CL, Patel AL, Meier PP, Garzon SA, Desai UR, Maheshwari A 2015 Aug American Journal of Physiology - Gastrointestinal and Liver Physiology 309 G171-G180

All-trans retinoic acid induces TGF-β2 in intestinal epithelial cells via RhoA- and p38α MAPK-mediated activation of the transcription factor ATF2

Namachivayam K, MohanKumar K, Arbach D, Jagadeeswaran R, Jain SK, Natarajan V, Mehta D, Jankov RP, Maheshwari A 2015 Jul PloS one 10

VEGF mRNA and protein concentrations in the developing human eye

Ma IT, McConaghy S, Namachivayam K, Halloran BA, Kurundkar AR, Mohankumar K, Maheshwari A, Ohls RK 2015 Apr Pediatric Research 77 500-505

Amniotic fluid-borne hepatocyte growth factor protects rat pups against experimental necrotizing enterocolitis

Jain SK, Baggerman EW, MohanKumar K, Namachivayam K, Jagadeeswaran R, Reyes VE, Maheshwari A 2014 Mar American Journal of Physiology - Gastrointestinal and Liver Physiology 306 G361-G369

Intestinal epithelial apoptosis initiates gut mucosal injury during extracorporeal membrane oxygenation in the newborn piglet

Mohankumar K, Killingsworth CR, Britt McIlwain R, Timpa JG, Jagadeeswaran R, Namachivayam K, Kurundkar AR, Kelly DR, Garzon SA, Maheshwari A 2014 Feb Laboratory Investigation 94 150-160

Preterm human milk contains a large pool of latent TGF-β, which can be activated by exogenous neuraminidase

Namachivayam K, Blanco CL, Frost BL, Reeves AA, Jagadeeswaran R, Mohankumar K, Safarulla A, Mandal P, Garzon SA, Raj JU, Maheshwari A 2013 Jun American Journal of Physiology - Gastrointestinal and Liver Physiology 304 G1055-G1065

Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis

Namachivayam K, Blanco CL, Mohankumar K, Jagadeeswaran R, Vasquez M, Mcgill-Vargas L, Garzon SA, Jain SK, Gill RK, Freitag NE, Weitkamp JH, Seidner SR, Maheshwari A 2013 Jan American Journal of Physiology - Gastrointestinal and Liver Physiology 304 G167-G180

Gut mucosal injury in neonates is marked by macrophage infiltration in contrast to pleomorphic infiltrates in adult: Evidence from an animal model

MohanKumar K, Kaza N, Jagadeeswaran R, Garzon SA, Bansal A, Kurundkar AR, Namachivayam K, Remon JI, Rekha Bandepalli C, Feng X, Weitkamp JH, Maheshwari A 2012 Jul American Journal of Physiology - Gastrointestinal and Liver Physiology 303 G93-G102

Absence of gastrointestinal pathogens in ileum tissue resected for necrotizing enterocolitis

Ullrich T, Tang YW, Correa H, Garzon SA, Maheshwari A, Hill M, Matta P, Krishnan MK, Weitkamp JH 2012 Apr Pediatric Infectious Disease Journal 31 413-414

Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling

Honavar J, Samal AA, Bradley KM, Brandon A, Balanay J, Squadrito GL, MohanKumar K, Maheshwari A, Postlethwait EM, Matalon S, Patel RP 2011 Aug American journal of respiratory cell and molecular biology 45 419-425

Activities of membrane bound phosphatases, transaminases and mitochondrial enzymes in white spot syndrome virus infected tissues of Fenneropenaeus indicus

Mohankumar K, Ramasamy P 2006 Jun Virus Research 118 130-135

White spot syndrome virus infection decreases the activity of antioxidant enzymes in Fenneropenaeus indicus

Mohankumar K, Ramasamy P 2006 Jan Virus Research 115 69-75