Cost Effectiveness of HCC screening

We have conducted cost-effectiveness studies showing that screening is cost-effective compared to no screening. We have also shown that biomarker-based screening would be cost-effective, depending on utilization, costs of tests, and sensitivity for early-stage HCC. Most recently, our group evaluated the cost-effectiveness of tailored (precision) HCC screening.

Szu-Yu Z, Sangha K, Fujiwara N, Hoshida Y, Parikh ND, Singal AG. Cost-effectiveness of a precision hepatocellular carcinoma surveillance strategy in patients with cirrhosis. Lancet eClinicalMedicine 2024; 75: 102755
Singal AG, Chhatwal J, Parikh ND, Tapper E. Cost-effectiveness of a biomarker-based screening strategy for hepatocellular carcinoma in patients with cirrhosis. Liver Cancer 2024; 13(6): 64-75.
Singal AG*, Parikh ND*, Hutton DW, Tapper EB. Cost effectiveness of hepatocellular carcinoma surveillance: An assessment of benefits and harms. Am J Gastro 2020; 115(10): 1642-49.