Health Care Delivery Research

Efficient delivery of proven health care interventions plays a critical role in outcomes for patients at-risk and with HCC. We have shown that delays in diagnosis and treatment, fragmentation of care, and disparities in access can significantly impact survival. We were one of the first groups to demonstrate the importance of multidisciplinary care to improve outcomes by streamlining care coordination.

Rao A*, Rich NE*, Marrero JA, Yopp AC, Singal AG. Diagnostic and Therapeutic Delays in Patients with Hepatocellular Carcinoma. Journal Nat Comp Cancer Network 2021; 19(9): 1063-1071
Mokdad A, Zhu H, Marrero JA, Mansour JC, Yopp AC*, Singal AG*. Hospital Volume and Survival after Hepatocellular Carcinoma Diagnosis. Am J Gastroenterology 2016; 111(7): 967-75.
Singal AG, Ghaziani T, Zhou K, Grinspan L, Benhammou J, Moon A, Yang JD, Salgia R, Pillai A, Zheng E, Rich N, Gopal P, Jalal P, Verna E, Yekkaluri S, Phen S, Melendez-Torres J, Alshuwaykh O, Choi H, Junus K, Grady J, Song M, Leven E, Yum J, Gowda V, Alsudaney M, Hernandez P, Desai N, Parikh ND. Recall patterns and risk of primary liver cancer for sub-centimeter ultrasound liver observations: A multicenter study. Hepatology Communications 2023; 7(3): e0073
Hester CA*, Karbhari N*, Rich NE, Augustine M, Mansour J, Polanco P, Porembka M, Wang S, Zeh HJ, Yopp AC*, Singal AG*. Effect of fragmentation of cancer care on treatment use and survival in hepatocellular carcinoma. Cancer 2019; 125(19): 3428-3436.
Yopp AC, Mansour J, Beg MS, Arenas J, Trimmer C, Reddick M, Pedrosa I, Khatri G, Yakoo T, Meyers JJ, Shaw J, Marrero JA, Singal AG. Establishment of a Multidisciplinary Hepatocellular Carcinoma Clinic is Associated with Improved Clinical Outcome. Annals of Surgical Oncology 2014; 21: 1287-95.
Desai R*, Jiang Y*, VanWagner L, Singal AG*, Lieber S*. Financial burden in a cohort of patients with hepatocellular carcinoma. Hepatology Communications 2024; 8(6): e0453
Louissaint J, Kyalwazi B, Deng J, Melendez-Torres J, Turer R, Hogan T, Tapper E, Yekkaluri S, Xie D, Rich NE, Singal AG. Patients with cirrhosis rapidly review potentially abnormal hepatocellular carcinoma surveillance results via the patient portal. Am J Gastro 2024; 119(11): 2331-2333.
Seif El Dahan K, Reczek A, Daher D, Rich N, Yang JD, Hsiehchen D, Zhu H, Patel M, Bayona Molano P, Sanford N, Gopal P, Parikh ND, Yopp A, Singal AG. Multidisciplinary care for patients with HCC: A systematic review and meta-analysis. Hepatology Communications 2023; 7(5): e0143.