Publications

10. Total Synthesis of Psammaplysins A, M, O, and Q, and Ceratinamide A.

Andrew P. Morrow and Myles W. Smith, J. Am. Chem. Soc. 2024, 146, 2913–2918.

9. Modular Total Synthesis of the 5/5-Spirocyclic Spiroindimicins.

Ankush Banerjee, Tiffany A. Brisco, Zhen Zhang, Alexander A. Busse, Krissty Sumida, and Myles W. Smith, Org. Lett. 2023, 25, 8413–8418.

8. Modular Total Synthesis of the 5/5-Spirocyclic Spiroindimicins.

Ankush Banerjee, Tiffany A. Brisco, Sneha Ray, Arani Datta, Xiaoyu Zhang, Zhen Zhang, Alexander A. Busse, Hanspeter Niederstrasser, Krissty Sumida, Bruce A. Posner, Dawn M. Wetzel, Margaret A. Phillips and Myles W. Smith, ChemRxiv 2023, Preprint.

7. Salvaging Salvinorin: From Hallucinogen to Potential Therapeutic through Chemical Synthesis. (Commentary)

Bhawyanth Duvvuru and Myles W. Smith, ACS Cent. Sci. 2023, 9, 1522–1524.

6. Synthetic Studies toward the Myrioneuron Alkaloids. (Invited Short Review)

Jake M. Aquilina and Myles W. Smith, Synthesis 2023, 55, 3725–3736.

5. 2,2-Disubstituted Indoxyls via Oxidative Dearomatization: Generalization to 2-Alkylindoles and Application to Alkaloid Synthesis. (Invited Synpact)

Fan Xu and Myles W. Smith, Synlett 2023, 34, 1539–1548.

4. Symmetry-Driven Total Synthesis of Myrioneurinol.

Jake M. Aquilina and Myles W. Smith, J. Am. Chem. Soc. 2022, 144, 11088–11093.

3. Dimerization decrypts antibiotic activity. (Commentary)

Myles W. Smith, Science 2022, 375, 820–821.

2. A General Approach to 2,2-Disubstituted Indoxyls: Total Synthesis of Brevianamide A and Trigonoliimine C.

Fan Xu and Myles W. Smith, Chem. Sci. 2021, 12, 13756–13763.

1. Total Synthesis of (+)-Spiroindimicin A and Congeners Unveils Their Antiparasitic Activity.

Zhen Zhang, Sneha Ray, Leah Imlay, Lauren T. Callaghan, Hanspeter Niederstrasser, Prema Latha Mallipeddi, Bruce A. Posner, Dawn M. Wetzel, Margaret A. Phillips and Myles W. Smith, Chem. Sci. 2021, 12, 10388–10394.

Prior to UTSW:

Enantioselective Cyclobutenylation of Olefins Using N-Sulfonyl-1,2,3-Triazoles as Vicinal Dicarbene Equivalents.

Patel, S. C.; Smith, M. W.; Mercer, J. A. M.; Suzuki, K.; Burns, N. Z. Org Lett. 2021, 23, 6530–6535.

Synthesis of (+)-Tacamonine via Stereoselective Radical Cyclization.

Smith, M. W.;* Ferreira, J.;* Hunter, R.; Venter, G. A.; Su, H. Org. Lett. 2019, 21, 8740–8745. (*equal contribution)

A convenient C–H functionalization platform for pyrroloiminoquinone alkaloid synthesis.

Smith, M. W.; Falck, I. D.; Ikemoto, H.; Burns, N. Z. Tetrahedron 2019, 75, 3366–3370.

A 7-Step Formal Asymmetric Total Synthesis of Strictamine via an Asymmetric Propargylation and Metal-Mediated Cyclization.

Smith, M. W.;* Zhou, Z.;* Gao, A. X.;* Shimbayashi, T.; Snyder, S. A. Org. Lett. 2017,19, 1004–1007. (*equal contribution)

Fe-Catalyzed C–C Bond Construction from Olefins via Radicals.

Lo, J. C.; Kim, D.; Pan, C. M.; Edwards, J. T.; Yabe, Y.; Gui, J.; Qin, T.; Gutiérrez, S.; Giacoboni, J.; Smith, M. W.; Holland, P. L.; Baran, P. S. J. Am. Chem. Soc. 2017, 139, 2484–2503.

Chemical Synthesis and Self-Assembly of a Ladderane Phospholipid.

Mercer, J. A,; Cohen, C. M.; Shuken, S. R.; Wagner, A. M.; Smith, M. W.; Moss F. R.; Smith, M. D.; Vahala, R.; Gonzalez-Martinez, A.; Boxer, S. G.; Burns, N. Z. J. Am. Chem. Soc. 2016, 138, 15845–15848.

Pyrone Diels-Alder Routes to Indolines and Hydroindolines: Syntheses of Gracilamine, Mesembrine, and Δ(7) -Mesembrenone.

Gan, P.; Smith, M. W.; Braffman, N. R.; Snyder, S. A. Angew. Chem. Int. Ed. 2016, 55, 3625–3630.

As simple as [2+2] (Commentary)

Smith, M. W.; Baran, P. S. Science 2015, 349, 925–926.

A Concise Total Synthesis of (+)-Scholarisine A Empowered by a Unique C–H Arylation.

Smith, M. W.; Snyder, S. A. J. Am. Chem. Soc. 2013, 135, 12964–12967.

A new approach to indolo[2,3-a]quinolizidines through radical cyclization of 2-acyl-1-phenylthiotetrahydro-ß-carbolines bearing pendent a,ß-unsaturated esters.

Smith, M. W.; Hunter, R.; Patten, D. J.; Hinz, W. Tetrahedron Lett. 2009, 50, 6342–6346.