Who We Are
The Clinical Trials Network Big South/West Node is a collaborative partnership between UT Southwestern Medical Center, UT Health Science Center, and University of California, Los Angeles.
With a $13.4 million grant (UG1DA020024-21), the Big South/West Node investigates novel interventions to improve outcomes for substance use disorders. The seven-year grant includes funding for UTSW to coordinate two large multicenter treatment studies using pharmacological approaches to assess efficacy for cocaine and methamphetamine use disorders.
Principal Investigators
Madhukar Trivedi, M.D.
Contact PI
Betty Jo Hay Distinguished Chair in Mental Health
Department of Psychiatry
UT Southwestern Medical Center
Steve Shoptaw, Ph.D.
Professor of Family Medicine and Psychiatry
Vice Chair of Research
Department of Family Medicine
University of California, Los Angeles
UCLA CBAM
Our Clinical Trials Network Studies
Randomized, Double-Blind, Active Placebo-Controlled Trial of Ketamine for Methamphetamine Use Disorder
Learn more about this study.
Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone:Improving the Real-World Effectiveness of Injection Naltrexone for Opioid Use Disorder (SWIFT)
Learn more about this study.
Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution (MBC4OUD)
Learn more about this study.
The use of respective Transcranial Magnetic Stimulation (rTMS) for Stimulant Use Disorders (STIMULUS)
Learn more about this study.
Randomized, Placebo-Controlled Trial of Extended-Release Naltrexone and Monthly Extended-Release Buprenorphine for Cocaine Use Disorder (CURB-2)
Learn more about this study.
Strategies to Enhance Recruitment and Retention of Black Individuals Into Clinical Trials for Substance Use Disorders (I-DREM)
Learn more about this study.
Remote Methadone Ingestion Surveillance Trial (RMIST)
Learn more about this study.
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