Ryder BD, Ustyantseva E, Boyer DR, Mendoza-Oliva A, Kuska MI, Wydorski PM, Macierzynska P, Morgan N, Sawaya MR, Diamond MI, Kampinga HH, Joachimiak LA,
2024 Mar
Structure
Mullapudi V, Vaquer-Alicea J, Bommareddy V, Vega AR, Ryder BD, White CL, Diamond MI, Joachimiak LA,
2023 Feb
Nat Commun
1
14
895
DnaJC7 binds natively folded structural elements in tau to inhibit amyloid formation.
Hou Z, Wydorski PM, Perez VA, Mendoza-Oliva A, Ryder BD, Mirbaha H, Kashmer O, Joachimiak LA, 2021 09 Nat Commun 1 12 5338Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone.
Ryder BD, Matlahov I, Bali S, Vaquer-Alicea J, van der Wel PCA, Joachimiak LA, 2021 02 Nat Commun 1 12 946Tau local structure shields an amyloid-forming motif and controls aggregation propensity.
Chen D, Drombosky KW, Hou Z, Sari L, Kashmer OM, Ryder BD, Perez VA, Woodard DR, Lin MM, Diamond MI, Joachimiak LA, 2019 06 Nat Commun 1 10 2493
Sari L, Bali S, Joachimiak LA, Lin MM,
2024 Mar
Nat Commun
1
15
2756
Multivalent coiled-coil interactions enable full-scale centrosome assembly and strength.
Rios MU, Bagnucka MA, Ryder BD, Ferreira Gomes B, Familiari NE, Yaguchi K, Amato M, Stachera WE, Joachimiak LA, Woodruff JB, 2024 Apr J Cell Biol 4 223Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds.
Hitt BD, Gupta A, Singh R, Yang T, Beaver JD, Shang P, White CL, Joachimiak LA, Diamond MI, 2023 Sep J Biol Chem 105252Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation.
Chlebowicz J, Russ W, Chen D, Vega A, Vernino S, White CL, Rizo J, Joachimiak LA, Diamond MI, 2023 Oct Sci Adv 43 9 eadh3457
Chen D, Bali S, Singh R, Wosztyl A, Mullapudi V, Vaquer-Alicea J, Jayan P, Melhem S, Seelaar H, van Swieten JC, Diamond MI, Joachimiak LA,
2023 Mar
Nat Commun
1
14
1625
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI,
2023 Jun
Elife
12
Disease-associated patterns of acetylation stabilize tau fibril formation.
Li L, Nguyen BA, Mullapudi V, Li Y, Saelices L, Joachimiak LA, 2023 Jun Structure
Marszalek J, De Los Rios P, Cyr D, Mayer MP, Adupa V, Andréasson C, Blatch GL, Braun JEA, Brodsky JL, Bukau B, Chapple JP, Conz C, Dementin S, Genevaux P, Genest O, Goloubinoff P, Gestwicki J, Hammond CM, Hines JK, Ishikawa K, Joachimiak LA, Kirstein J, Liberek K, Mokranjac D, Nillegoda N, Ramos CHI, Rebeaud M, Ron D, Rospert S, Sahi C, Shalgi R, Tomiczek B, Ushioda R, Ustyantseva E, Ye Y, Zylicz M, Kampinga HH,
2023 Dec
Cell Stress Chaperones
1
29
21-33
Humphreys JM, Teixeira LR, Akella R, He H, Kannangara AR, Sekulski K, Pleinis J, Liwocha J, Jiou J, Servage KA, Orth K, Joachimiak L, Rizo J, Cobb MH, Brautigam CA, Rodan AR, Goldsmith EJ,
2023 Aug
Mol Biol Cell
mbcE23030113
Wydorski PM, Osipiuk J, Lanham BT, Tesar C, Endres M, Engle E, Jedrzejczak R, Mullapudi V, Michalska K, Fidelis K, Fushman D, Joachimiak A, Joachimiak LA,
2023 Apr
Nat Commun
1
14
2366
Chen D, Joachimiak LA,
2023
Methods Mol Biol
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Nakahara E, Mullapudi V, Collier GE, Joachimiak LA, Hulleman JD,
2022 Sep
ACS Chem Biol
Wickramaratne AC, Li L, Hopkins JB, Joachimiak LA, Green CB,
2022 May
Biochemistry
Seed-competent tau monomer initiates pathology in a tauopathy mouse model.
Mirbaha H, Chen D, Mullapudi V, Terpack SJ, White CL, Joachimiak LA, Diamond MI, 2022 Jun J Biol Chem 102163
Ryder BD, Wydorski PM, Hou Z, Joachimiak LA,
2022 Jan
Trends Biochem Sci
Joachimiak LA,
2022 Aug
Structure
8
30
1045-1047
Modifying Amyloid Motif Aggregation Through Local Structure.
Bali S, Joachimiak LA, 2022 Methods Mol Biol 2340 343-356
Hou Z, Chen D, Ryder BD, Joachimiak LA,
2021 Jun
Sci Rep
1
11
13602
Vaquer-Alicea J, Diamond MI, Joachimiak LA,
2021 Apr
Acta Neuropathol
Gestaut D, Roh SH, Ma B, Pintilie G, Joachimiak LA, Leitner A, Walzthoeni T, Aebersold R, Chiu W, Frydman J,
2019 Apr
Cell
3
177
751-765.e15
Gestaut D, Limatola A, Joachimiak L, Frydman J,
2019 Apr
Curr. Opin. Struct. Biol.
55
50-58
Inert and seed-competent tau monomers suggest structural origins of aggregation.
Mirbaha H, Chen D, Morazova OA, Ruff KM, Sharma AM, Liu X, Goodarzi M, Pappu RV, Colby DW, Mirzaei H, Joachimiak LA, Diamond MI 2018 Jul Elife 7Structure and Dynamics of the Huntingtin Exon-1 N-Terminus: A Solution NMR Perspective.
Baias M, Smith PE, Shen K, Joachimiak LA, Zerko S, Kozminski W, Frydman J, Frydman L 2017 Jan J. Am. Chem. Soc. 3 139 1168-1176
Walzthoeni T, Joachimiak LA, Rosenberger G, Röst HL, Malmström L, Leitner A, Frydman J, Aebersold R
2015 Dec
Nat. Methods
12
12
1185-90
The structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCT.
Joachimiak LA, Walzthoeni T, Liu CW, Aebersold R, Frydman J 2014 Nov Cell 5 159 1042-55
Leitner A, Joachimiak LA, Unverdorben P, Walzthoeni T, Frydman J, Förster F, Aebersold R
2014 Jul
Proc. Natl. Acad. Sci. U.S.A.
26
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Sontag EM, Joachimiak LA, Tan Z, Tomlinson A, Housman DE, Glabe CG, Potkin SG, Frydman J, Thompson LM
2013 Feb
Proc. Natl. Acad. Sci. U.S.A.
8
110
3077-82
Reissmann S, Joachimiak LA, Chen B, Meyer AS, Nguyen A, Frydman J
2012 Oct
Cell Rep
4
2
866-77
The molecular architecture of the eukaryotic chaperonin TRiC/CCT.
Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J 2012 May Structure 5 20 814-25
Zhang J, Ma B, DiMaio F, Douglas NR, Joachimiak LA, Baker D, Frydman J, Levitt M, Chiu W
2011 May
Structure
5
19
633-9
A de novo protein binding pair by computational design and directed evolution.
Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D 2011 Apr Mol. Cell 2 42 250-60
Tam S, Spiess C, Auyeung W, Joachimiak L, Chen B, Poirier MA, Frydman J
2009 Dec
Nat. Struct. Mol. Biol.
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Keeble AH, Joachimiak LA, Maté MJ, Meenan N, Kirkpatrick N, Baker D, Kleanthous C
2008 Jun
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Joachimiak LA, Kortemme T, Stoddard BL, Baker D
2006 Aug
J. Mol. Biol.
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Nair BM, Joachimiak LA, Chattopadhyay S, Montano I, Burns JL
2005 Apr
FEMS Microbiol. Lett.
2
245
337-44
Computational redesign of protein-protein interaction specificity.
Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D 2004 Apr Nat. Struct. Mol. Biol. 4 11 371-9