Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases

Calvier L, Alexander A, Marckx AT, Kounnas MZ, Durakoglugil M, Herz J 2024 Apr Cells 13

Reelin through the years: From brain development to inflammation

Alexander A, Herz J, Calvier L 2023 Jun Cell Reports 42

Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases

Calvier L, Drelich A, Hsu J, Tseng CT, Mina Y, Nath A, Kounnas MZ, Herz J 2023 Frontiers in immunology 14

The “6B” Strategy: Build Back a Better Blood–Brain Barrier

Calvier L, Alexander AE, Herz J 2022 Sep Immuno 2 506-511

Editorial: New Advances in Cardiorenal Syndrome

Calvier L, Kökény G, Martinez-Martinez E 2022 Jul Frontiers in Cardiovascular Medicine 9

Interplay of Low-Density Lipoprotein Receptors, LRPs, and Lipoproteins in Pulmonary Hypertension

Calvier L, Herz J, Hansmann G 2022 Feb JACC: Basic to Translational Science 7 164-180

PPARγ and TGFβ—Major regulators of metabolism, inflammation, and fibrosis in the lungs and kidneys

Kökény G, Calvier L, Hansmann G 2021 Oct International journal of molecular sciences 22

Reelin changes hippocampal learning in aging and Alzheimer's disease

Marckx AT, Fritschle KE, Calvier L, Herz J 2021 Sep Behavioural Brain Research 414

Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitis

Calvier L, Manouchehri N, Sacharidou A, Mineo C, Shaul PW, Hui DY, Kounnas MZ, Stüve O, Herz J 2021 Aug Science Immunology 6

CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent CNS autoimmunity

Manouchehri N, Hussain RZ, Cravens PD, Esaulova E, Artyomov MN, Edelson BT, Wu GF, Cross AH, Doelger R, Loof N, Eagar TN, Forsthuber TG, Calvier L, Herz J, Stüve O 2021 Apr Proceedings of the National Academy of Sciences of the United States of America 118

Reelin Depletion Protects Against Atherosclerosis by Decreasing Vascular Adhesion of Leukocytes

Calvier L, Xian X, Lee RG, Sacharidou A, Mineo C, Shaul PW, Kounnas MZ, Tsai S, Herz J 2021 Apr Arteriosclerosis, thrombosis, and vascular biology 41 1309-1318

Reelin depletion protects against autoimmune encephalomyelitis by decreasing vascular adhesion of leukocytes

Calvier L, Demuth G, Manouchehri N, Wong C, Sacharidou A, Mineo C, Shaul PW, Monson NL, Kounnas MZ, Stüve O, Herz J 2020 Aug Science translational medicine 12

PPARγ is a gatekeeper for extracellular matrix and vascular cell homeostasis: Beneficial role in pulmonary hypertension and renal/cardiac/pulmonary fibrosis

Kökény G, Calvier L, Legchenko E, Chouvarine P, Mózes MM, Hansmann G 2020 Mar Current opinion in nephrology and hypertension 29 171-179

Activation of the metabolic master regulator PPARg: A potential pioneering therapy for pulmonary arterial hypertension

Hansmann G, Calvier L, Risbano MG, Chan SY 2020 American journal of respiratory cell and molecular biology 62 143-156

The PPARγagonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3

Németh Á, Mózes MM, Calvier L, Hansmann G, Kökény G 2019 Jul BMC nephrology 20

LRP1 Deficiency in Vascular SMC Leads to Pulmonary Arterial Hypertension That Is Reversed by PPARγ Activation

Calvier L, Boucher P, Herz J, Hansmann G 2019 Jun Circulation research 124 1778-1785

Chronic TGF-b1 signaling in pulmonary arterial hypertension induces sustained canonical Smad3 pathways in vascular smooth muscle cells

Calvier L, Chouvarine P, Legchenko E, Kokeny G, Mozes MM, Hansmann G 2019 American journal of respiratory cell and molecular biology 61 121-123

Galectin-3 pharmacological inhibition attenuates early renal damage in spontaneously hypertensive rats

Martínez-Martínez E, Ibarrola J, Fernández-Celis A, Calvier L, Leroy C, Cachofeiro V, Rossignol P, López-Andrés N 2018 Feb Journal of hypertension 36 368-376

Transforming growth factor β1-and bone morphogenetic protein 2/PPARγ-regulated MicroRNAs in pulmonary arterial hypertension

Calvier L, Chouvarine P, Legchenko E, Hansmann G 2017 Nov American journal of respiratory and critical care medicine 196 1227-1228

PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism

Calvier L, Chouvarine P, Legchenko E, Hoffmann N, Geldner J, Borchert P, Jonigk D, Mozes MM, Hansmann G 2017 May Cell Metabolism 25 1118-1134.e7

Galectin-3 blockade reduces renal fibrosis in two normotensive experimental models of renal damage

Martinez-Martinez E, Ibarrola J, Calvier L, Fernandez-Celis A, Leroy C, Cachofeiro V, Rossignol P, Lopez-Andres N 2016 Nov PloS one 11

Galectin-3 inhibition prevents adipose tissue remodelling in obesity

Martínez-Martínez E, Calvier L, Rossignol P, Rousseau E, Fernández-Celis A, Jurado-López R, Laville M, Cachofeiro V, López-Andrés N 2016 Jun International Journal of Obesity 40 1034-1038

Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension

Calvier L, Legchenko E, Grimm L, Sallmon H, Hatch A, Plouffe BD, Schroeder C, Bauersachs J, Murthy SK, Hansmann G 2016 Mar Heart 102 390-396

Galectin-3 blockade inhibits cardiac inflammation and fibrosis in experimental hyperaldosteronism and hypertension

Martínez-Martínez E, Calvier L, Fernández-Celis A, Rousseau E, Jurado-López R, Rossoni LV, Jaisser F, Zannad F, Rossignol P, Cachofeiro V, López-Andrés N 2015 Oct Hypertension 66 767-775

Interleukin-33/ST2 system attenuates aldosterone-induced adipogenesis and inflammation

Martínez-Martínez E, Cachofeiro V, Rousseau E, Álvarez V, Calvier L, Fernández-Celis A, Leroy C, Miana M, Jurado-López R, Briones AM, Jaisser F, Zannad F, Rossignol P, López-Andrés N 2015 Aug Molecular and Cellular Endocrinology 411 20-27

The impact of galectin-3 inhibition on aldosterone-induced cardiac and renal injuries

Calvier L, Martinez-Martinez E, Miana M, Cachofeiro V, Rousseau E, Sádaba JR, Zannad F, Rossignol P, López-Andrés N 2015 Jan JACC: Heart Failure 3 59-67

Galectin-3 mediates aldosterone-induced vascular fibrosis

Calvier L, Miana M, Reboul P, Cachofeiro V, Martinez-Martinez E, De Boer RA, Poirier F, Lacolley P, Zannad F, Rossignol P, López-Andrés N 2013 Jan Arteriosclerosis, thrombosis, and vascular biology 33 67-75

Absence of cardiotrophin 1 is associated with decreased age-dependent arterial stiffness and increased longevity in mice

López-Andrés N, Calvier L, Labat C, Fay R, Díez J, Benetos A, Zannad F, Lacolley P, Rossignol P 2013 Jan Hypertension 61 120-129

Cardiotrophin 1 is involved in cardiac, vascular, and renal fibrosis and dysfunction

López-Andrés N, Rousseau A, Akhtar R, Calvier L, Iñigo C, Labat C, Zhao X, Cruickshank K, Díez J, Zannad F, Lacolley P, Rossignol P 2012 Aug Hypertension 60 563-573