Publications

Moving the Needle in Perinatal Asphyxia

Chalak LF 2024 Sep Clinics in Perinatology 51 xxi-xxiii

Reverse Therapy: Impact of Hyperthermia and Rewarming on Newborn Outcomes

Chalak LF, Davidson JO, Gunn AJ 2024 Sep Clinics in Perinatology 51 565-572

Key Inflammatory Biomarkers in Perinatal Asphyxia: A Comprehensive Review

Bitar L, Stonestreet BS, Chalak LF 2024 Sep Clinics in Perinatology 51 617-628

Prognostic value of quantitative EEG in early hours of life for neonatal encephalopathy and neurodevelopmental outcomes

Kota S, Kang S, Liu YL, Liu H, Montazeri S, Vanhatalo S, Chalak LF 2024 Aug Pediatric Research 96 685-694

Perinatal asphyxia impact on networks of cortical activity

Kota S, Chalak L 2024 Jul Pediatric Research 96 17-18

Postnatal Cerebral Hemodynamics and Placental Vascular Malperfusion Lesions in Neonates With Congenital Heart Disease

Leon RL, Bitar L, Sharma K, Mir IN, Chalak LF 2024 Jul Pediatric Neurology 156 72-78

Association between decreased cord blood inter-alpha inhibitor levels and neonatal encephalopathy at birth

Bitar L, Stonestreet BS, Lim YP, Qiu J, Chen X, Mir IN, Chalak LF 2024 Jun Early Human Development 193

Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial

Author Collaboration HT, Mietzsch U, Kolnik SE, Wood TR, Natarajan N, Gonzalez FF, Glass H, Mayock DE, Bonifacio SL, Van Meurs K, Comstock BA, Heagerty PJ, Wu TW, Wu YW, Juul SE, Ahmad KA, Baserga M, Bendel-Stenzel E, Benninger KL, Chalak L, Chang T, Flibotte J, Lampland AL, Maitre NL, Mathur AM, Merhar S, Poindexter BB, Rao R, Riley D, Smyser CD, Sokol GM, Weitkamp JH, Yanowitz T 2024 May Archives of Disease in Childhood: Fetal and Neonatal Edition 109 308-316

Development of neonatal connectome dynamics and its prediction for cognitive and language outcomes at age 2

Xu Y, Liao X, Lei T, Cao M, Zhao J, Zhang J, Zhao T, Li Q, Jeon T, Ouyang M, Chalak L, Rollins N, Huang H, He Y 2024 May Cerebral Cortex 34

Genetic and Congenital Anomalies in Infants With Hypoxic-Ischemic Encephalopathy

Morell AS, Monsell SE, Cornet MC, Wisnowski JL, McKinstry RC, Mathur AM, Li Y, Glass HC, Gonzalez FF, Mayock DE, Benninger KL, Van Meurs KP, Lampland AL, Wu TW, Riley D, Mietzsch U, Chalak L, Flibotte J, Weitkamp JH, Ahmad KA, Yanowitz TD, Baserga M, Merhar S, Rao R, Sokol GM, Comstock BA, Heagerty PJ, Juul SE, Wu YW 2024 May Pediatric Neurology 154 44-50

A Comparison of Criteria for Defining Metabolic Acidemia in Live-Born Neonates and Its Effect on Predicting Serious Adverse Neonatal Outcomes

Kraus AC, Saucedo AM, Byrne JJ, Chalak LF, Pruszynski JE, Spong CY 2024 Apr Obstetrical and Gynecological Survey 79 189-191

Human Parechovirus (HPeV) infections: clinical presentations, patterns, and evolution of neonatal brain injury

Oren MS, Clarke RL, Price M, Thomas JM, Machie M, Dolce AM, Chalak LF, Angelis D 2024 Apr Journal of Perinatology 44 581-583

Development of sensorimotor-visual connectome gradient at birth predicts neurocognitive outcomes at 2 years of age

Xia Y, Zhao J, Xu Y, Duan D, Xia M, Jeon T, Ouyang M, Chalak L, Rollins N, Huang H, He Y 2024 Feb iScience 27

Asperger’s syndrome – about time to rename it?

Bearer C, Abman SH, Agostoni C, Ballard P, Bliss J, de Boode WP, Canpolat FE, Chalak L, Cilio MR, Dammann O, Davis J, El-Metwally D, Ferriero D, Ford S, Fuentes-Afflick E, Gano D, Giussani D, Gonzalez F, Gunn A, Hogeveen M, Huang AY, Kaplan J, Klebanoff M, Lachman P, Mak R, Malhotra A, Miller S, Mitchell WB, Molloy E, Mulkey SB, Roland D, Sampath V, Sant’Anna G, Schaff P, Singer LT, Stroustrup A, Tingay D, Tiribelli C, Toldi G, Tryggestad J, Valente EM, Wilson-Costello D, Zupancic J 2024 Feb Pediatric Research 95 582-584

Corrigendum to ‘A comparison of criteria for defining metabolic acidemia in live born neonates and its effect on predicting serious adverse neonatal outcomes’. [American Journal of Obstetrics and Gynecology 229/4 (2023) 439-440](S0002937823001941)(10.1016/j.ajog.2023.03.031)

Kraus AC, Saucedo AM, Byrne JJ, Chalak LF, Pruszynski JE, Spong CY 2024 Jan American journal of obstetrics and gynecology 230 108

Neurodevelopmental outcomes in extremely preterm infants with placental pathologic evidence of fetal inflammatroy response

Alayli Y, Brown LS, Tolentino-Plata K, Leon R, Heyne R, Chalak LF, Mir IN 2024 Pediatric Research

A New Horizon for Understanding the Comparative Effectiveness for Cooling Prospectively Infants with Mild Encephalopathy

Chalak LF, Slaughter JL, King WC, Sepulveda P, Wisniewski SR 2024 Clinics in Perinatology 51 605-616

Neonatal encephalopathy and hypoxic–ischemic encephalopathy: moving from controversy to consensus definitions and subclassification

Molloy EJ, Branagan A, Hurley T, Quirke F, Devane D, Taneri PE, El-Dib M, Bloomfield FH, Maeso B, Pilon B, Bonifacio SL, Wusthoff CJ, Chalak L, Bearer C, Murray DM, Badawi N, Campbell S, Mulkey S, Gressens P, Ferriero DM, de Vries LS, Walker K, Kay S, Boylan G, Gale C, Robertson NJ, D’Alton M, Gunn A, Nelson KB 2023 Dec Pediatric Research 94 1860-1863

Evaluation of heterogeneity in effect of therapeutic hypothermia by sex among infants with neonatal encephalopathy

Sewell EK, Shankaran S, Natarajan G, Laptook A, Das A, McDonald SA, Hamrick S, Baack M, Rysavy M, Higgins RD, Chalak L, Patel RM 2023 Oct Pediatric Research 94 1380-1384

A comparison of criteria for defining metabolic acidemia in live-born neonates and its effect on predicting serious adverse neonatal outcomes

Kraus AC, Saucedo AM, Byrne JJ, Chalak LF, Pruszynski JE, Spong CY 2023 Oct American journal of obstetrics and gynecology 229 439.e1-439.e11

Tissue Oxygenation Changes after Transfusion and Outcomes in Preterm Infants: A Secondary Near-Infrared Spectroscopy Study of the Transfusion of Prematures Randomized Clinical Trial (TOP NIRS)

Chock VY, Kirpalani H, Bell EF, Tan S, Hintz SR, Ball MB, Smith E, Das A, Loggins YC, Sood BG, Chalak LF, Wyckoff MH, Kicklighter SD, Kennedy KA, Patel RM, Carlo WA, Johnson KJ, Watterberg KL, Sánchez PJ, Laptook AR, Seabrook RB, Cotten CM, Mancini T, Sokol GM, Ohls RK, Hibbs AM, Poindexter BB, Reynolds AM, Demauro SB, Chawla S, Baserga M, Walsh MC, Higgins RD, Van Meurs KP 2023 Sep JAMA Network Open 6 E2334889

Commentary to Adverse short- and long-term outcomes among infants with mild neonatal encephalopathy PR-2022-0126

Chalak LF 2023 Sep Pediatric Research 94 866-867

Sex Vulnerabilities to Hypoxia-Ischemia at Birth

Chalak LF, Pruszynski JE, Spong CY 2023 Aug JAMA Network Open 6 e2326542

Evaluation of neurovascular coupling during neuroprotective therapies: A single site HEAL ancillary study

Chalak LF, Kang S, Kota S, Liu H, Liu Y, Juul SE, Wu YW 2023 Aug Early Human Development 183

Antiseizure medication at discharge in infants with hypoxic-ischaemic encephalopathy: An observational study

Sewell EK, Shankaran S, McDonald SA, Hamrick S, Wusthoff CJ, Adams-Chapman I, Chalak LF, Davis AS, Van Meurs K, Das A, Maitre N, Laptook A, Patel RM 2023 Jul Archives of Disease in Childhood: Fetal and Neonatal Edition 108 421-428

Hypoxic-Ischemic Encephalopathy: Changing Outcomes Across the Spectrum

Pappas A, Milano G, Chalak LF 2023 Mar Clinics in Perinatology 50 31-52

Placental clearance not synthesis tempers exaggerated pro-inflammatory cytokine response in neonates exposed to chorioamnionitis

Mir IN, Uddin N, Liao J, Brown LS, Leon R, Chalak LF, Savani RC, Rosenfeld CR 2023 Feb Pediatric Research 93 675-681

Vein of Galen aneurysmal malformation: rationalizing medical management of neonatal heart failure

Cory MJ, Durand P, Sillero R, Morin L, Savani R, Chalak L, Angelis D 2023 Jan Pediatric Research 93 39-48

Cerebral Oximetry Monitoring in Extremely Preterm Infants

Hansen ML, Pellicer A, Hyttel-Sørensen S, Ergenekon E, Szczapa T, Hagmann C, Naulaers G, Mintzer J, Fumagalli M, Dimitriou G, Dempsey E, Tkaczyk J, Cheng G, Fredly S, Heuchan AM, Pichler G, Fuchs H, Nesargi S, Hahn GH, Piris-Borregas S, Širc J, Alsina-Casanova M, Stocker M, Ozkan H, Sarafidis K, Hopper AO, Karen T, Rzepecka-Weglarz B, Oguz SS, Arruza L, Memisoglu AC, Del Rio Florentino R, Baserga M, Maton P, Truttmann AC, De Las Cuevas I, Agergaard P, Zafra P, Bender L, Lauterbach R, Lecart C, De Buyst J, El-Khuffash A, Curley A, Vaccarello OO, Miletin J, Papathoma E, Vesoulis Z, Vento G, Cornette L, Lopez LS, Yasa B, Klamer A, Agosti M, Baud O, Mastretta E, Cetinkaya M, McCall K, Zeng S, Hatzidaki E, Bargiel A, Marciniak S, Gao X, Huijia L, Chalak L, Yang L, Rao SA, Xu X, Gonzalez BL, Wilinska M, Yin Z, Sadowska-Krawczenko I, Serrano-Viñuales I, Krolak-Olejnik B, Ybarra MM, Morales-Betancourt C, Korček P, Teresa-Palacio M, Mosca F, Hergenhan A, Koksal N, Tsoni K, Kadri MM, Knöpfli C, Rafinska-Wazny E, Akin MS, Nordvik T, Peng Z, Kersin SG, Thewissen L, Alarcon A, Healy D, Urlesberger B, Baş M, Baumgartner J, Skylogianni E, Karadyova V, Valverde E, Bergon-Sendin E, Kucera J, Pisoni S, Wang L, Smits A, Sanchez-Salmador R, Rasmussen MI, Olsen MH, Jensen AK, Gluud C, Jakobsen JC, Greisen G 2023 New England Journal of Medicine 388 1501-1511

"Mild'' Hypoxic-Ischaemic Encephalopathy and Therapeutic Hypothermia: A Survey of Clinical Practice and Opinion from 35 Countries

Singla M, Chalak L, Kumar K, Hayakawa M, Mehta S, Neoh SH, Kitsommart R, Yuan Y, Zhang H, Shah PS, Smyth J, Wandita S, Yeo KT, Lim G, Oei JL 2022 Dec Neonatology 119 712-718

Mild hypoxic-ischemic encephalopathy (HIE): timing and pattern of MRI brain injury

Li Y, Wisnowski JL, Chalak L, Mathur AM, McKinstry RC, Licona G, Mayock DE, Chang T, Van Meurs KP, Wu TW, Ahmad KA, Cornet MC, Rao R, Scheffler A, Wu YW 2022 Dec Pediatric Research 92 1731-1736

The effects of betamethasone on the amplitude integrated EEG of infants born at 34- or 35-weeks gestation

Author Collaboration EK, Author Collaboration EK, Laptook AR, Chalak L, Pappas A, Davis A, Sanchez PJ, Van Meurs KP, Oh W, Sommers R, Shankaran S, Hensman AM, Rouse DJ, McDonald S, Das A, Goldberg RN, Ambalavanan N, Gyamfi-Bannerman C, Thom EA, Higgins RD, Laptook AR, Chalak L, Pappas A, Davis A, Sanchez PJ, Van Meurs KP, Oh W, Shankaran S, Hensman AM, McDonald S, Das A, Goldberg RN, Ambalavanan N, Higgins RD, Rouse DJ, Gyamfi-Bannerman C, Thom EA 2022 Dec Journal of Perinatology 42 1615-1621

Neuroprotection for hypoxic-ischemic encephalopathy: Contributions from the neonatal research network

Bonifacio SL, Chalak LF, Van Meurs KP, Laptook AR, Shankaran S 2022 Nov Seminars in Perinatology 46

Placental vascular malperfusion lesions in fetal congenital heart disease

Leon RL, Sharma K, Mir IN, Herrera CL, Brown SL, Spong CY, Chalak LF 2022 Oct American journal of obstetrics and gynecology 227 620.e1-620.e8

Early brain and abdominal oxygenation in extremely low birth weight infants

Author Collaboration ft, Chock VY, Smith E, Tan S, Ball MB, Das A, Hintz SR, Kirpalani H, Bell EF, Chalak LF, Carlo WA, Cotten CM, Widness JA, Kennedy KA, Ohls RK, Seabrook RB, Patel RM, Laptook AR, Mancini T, Sokol GM, Walsh MC, Yoder BA, Poindexter BB, Chawla S, D’Angio CT, Higgins RD, Van Meurs KP 2022 Oct Pediatric Research 92 1034-1041

Placental pathologic lesions associated with stroke in term neonates

Leon RL, Kalvacherla V, Andrews MM, Thomas JM, Mir IN, Chalak LF 2022 Sep Frontiers in Endocrinology 13

A phase-II clinical trial of targeted cerebral near infrared spectroscopy using standardized treatment guidelines to improve brain oxygenation in preterm infants (BOx-II): A study protocol

Vesoulis Z, Hopper A, Fairchild K, Zanelli S, Chalak L, Noroozi M, Liu J, Chock V 2022 Sep Contemporary Clinical Trials 120

Trial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns

Wu YW, Comstock BA, Gonzalez FF, Mayock DE, Goodman AM, Maitre NL, Chang T, van Meurs KP, Lampland AL, Bendel-Stenzel E, Mathur AM, Wu TW, Riley D, Mietzsch U, Chalak L, Flibotte J, Weitkamp JH, Ahmad KA, Yanowitz TD, Baserga M, Poindexter BB, Rogers EE, Lowe JR, Kuban KC, O’Shea TM, Wisnowski JL, McKinstry RC, Bluml S, Bonifacio S, Benninger KL, Rao R, Smyser CD, Sokol GM, Merhar S, Schreiber MD, Glass HC, Heagerty PJ, Juul SE 2022 Jul New England Journal of Medicine 387 148-159

Feasibility of EEG Phase‐Amplitude Coupling to Stratify Encephalopathy Severity in Neonatal HIE Using Short Time Window

Wang X, Liu H, Ortigoza EB, Kota S, Liu Y, Zhang R, Chalak LF 2022 Jul Brain Sciences 12

Identification and Treatment of Neonatal Seizures during Therapeutic Hypothermia and Rewarming - Reply

Chalak LF 2022 May JAMA neurology 79 530-531

Neuroplacentology in congenital heart disease: placental connections to neurodevelopmental outcomes

Leon RL, Mir IN, Herrera CL, Sharma K, Spong CY, Twickler DM, Chalak LF 2022 Mar Pediatric Research 91 787-794

New Horizons in Mild Hypoxic-ischemic Encephalopathy: A Standardized Algorithm to Move past Conundrum of Care

Chalak L 2022 Mar Clinics in Perinatology 49 279-294

The impact of the COVID pandemic on prematurity rates: Conflicting results, publication ethics and academic frustration

Greisen G, Chalak L, Hansen ML, Rasmussen MI 2022 Feb Acta Paediatrica, International Journal of Paediatrics 111 269-271

EEG phase-amplitude coupling to stratify encephalopathy severity in the developing brain

Wang X, Liu H, Kota S, Das Y, Liu Y, Zhang R, Chalak L 2022 Feb Computer Methods and Programs in Biomedicine 214

Cerebral Blood Flow Monitoring in High-Risk Fetal and Neonatal Populations

Leon RL, Ortigoza EB, Ali N, Angelis D, Wolovits JS, Chalak LF 2022 Jan Frontiers in Pediatrics 9

A neonatal neuroNICU collaborative approach to neuromonitoring of posthemorrhagic ventricular dilation in preterm infants

Whittemore BA, Swift DM, M. Thomas J, F. Chalak L 2022 Jan Pediatric Research 91 27-34

Correction: The american pediatric society and society for pediatric research joint statement against racism and social injustice (Pediatric Research, (2022), 91, 1, (72), 10.1038/s41390-020-01107-9)

Abman SH, Armstrong S, Baker S, Bogue CW, Carlo W, Chalak L, Daniels SR, Davis S, Debaun MR, Fike C, Frazer L, Gibson K, Gill M, Glass H, Gordon CM, Goyal M, Hirschhorn J, Holtz L, Hunstad DA, Leonard MB, Maitre N, Markham L, McAllister-Lucas L, Orange J, Shah P, Simon T, Steinhorn RH, Tarini B, Walker-Harding LR 2022 Jan Pediatric Research 91 264

The american pediatric society and society for pediatric research joint statement against racism and social injustice

Abman SH, Armstrong S, Baker S, Bogue CW, Carlo W, Chalak L, Daniels SR, Davis S, Debaun MR, Fike C, Frazer L, Gibson K, Gill M, Glass H, Gordon CM, Goyal M, Hirschhorn J, Holtz L, Hunstad DA, Leonard MB, Maitre N, Markham L, McAllister-Lucas L, Orange J, Shah P, Simon T, Steinhorn RH, Tarini B, Walker-Harding LR 2022 Jan Pediatric Research 91 72

Stakeholder engagement in neonatal clinical trials: an opportunity for mild neonatal encephalopathy research

Chalak L, Pilon B, Byrne R, Maitre N 2022 Pediatric Research

Erratum: Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Association between increased seizures during rewarming after hypothermia for neonatal hypoxic ischemic encephalopathy and abnormal neurodevelopmental outcomes at 2-year follow-up: a nested multisite cohort study (JAMA Neurol (2021) DOI: 10.1001/jamaneurol.2021.3723)

Chalak LF, Pappas A, Tan S 2021 Dec JAMA neurology 78 1533

Central data monitoring in the multicentre randomised SafeBoosC-III trial – a pragmatic approach

Author Collaboration TS, Olsen MH, Hansen ML, Safi S, Jakobsen JC, Greisen G, Gluud C, Pellicer A, Bargiel A, Hopper A, Truttmann A, Klamer A, Heuchan AM, Memisoglu A, Krolak-Olejnik B, Rzepecka B, Loureiro B, Lecart C, Hagmann C, Ergenekon E, Hatzidaki E, Mastretta E, Dempsey E, Papathoma E, Lou F, Dimitriou G, Pichler G, Vento G, Hahn GH, Naulaers G, Cheng G, Fuchs H, Ozkan H, De Las Cuevas I, Sadowska-Krawczenko I, Tkaczyk J, Sirc J, Zhang J, Mintzer J, De Buyst J, McCall K, Bober K, Sarafidis K, Bender L, Lopez LS, Chalak L, Yang L, Cornette L, Arruza L, Baserga M, Stocker M 2021 Dec BMC Medical Research Methodology 21

Neurovascular coupling (NVC) in newborns using processed EEG versus amplitude-EEG

Das Y, Wang X, Kota S, Zhang R, Liu H, Chalak LF 2021 Dec Scientific reports 11

Association between Increased Seizures during Rewarming after Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy and Abnormal Neurodevelopmental Outcomes at 2-Year Follow-up: A Nested Multisite Cohort Study

Chalak LF, Pappas A, Tan S, Das A, Sánchez PJ, Laptook AR, Van Meurs KP, Shankaran S, Bell EF, Davis AS, Heyne RJ, Pedroza C, Poindexter BB, Schibler K, Tyson JE, Ball MB, Bara R, Grisby C, Sokol GM, D'Angio CT, Hamrick SE, Dysart KC, Cotten CM, Truog WE, Watterberg KL, Timan CJ, Garg M, Carlo WA, Higgins RD 2021 Dec JAMA neurology 78 1484-1493

Early Use of Transcranial Doppler Ultrasonography to Stratify Neonatal Encephalopathy

Natique KR, Das Y, Maxey MN, Sepulveda P, Brown LS, Chalak LF 2021 Nov Pediatric Neurology 124 33-39

Bedside and laboratory neuromonitoring in neonatal encephalopathy

Chalak L, Hellstrom-Westas L, Bonifacio S, Tsuchida T, Chock V, El-Dib M, Massaro AN, Garcia-Alix A 2021 Oct Seminars in Fetal and Neonatal Medicine 26

Unanswered questions regarding therapeutic hypothermia for neonates with neonatal encephalopathy

Author Collaboration NB, Sabir H, Bonifacio SL, Gunn AJ, Thoresen M, Chalak LF 2021 Oct Seminars in Fetal and Neonatal Medicine 26

Acute and Chronic Placental Abnormalities in a Multicenter Cohort of Newborn Infants with Hypoxic–Ischemic Encephalopathy

Chalak L, Redline RW, Goodman AM, Juul SE, Chang T, Yanowitz TD, Maitre N, Mayock DE, Lampland AL, Bendel-Stenzel E, Riley D, Mathur AM, Rao R, Van Meurs KP, Wu TW, Gonzalez FF, Flibotte J, Mietzsch U, Sokol GM, Ahmad KA, Baserga M, Weitkamp JH, Poindexter BB, Comstock BA, Wu YW 2021 Oct Journal of Pediatrics 237 190-196

EEG Spectral Power: A Proposed Physiological Biomarker to Classify the Hypoxic-Ischemic Encephalopathy Severity in Real Time

Kota S, Jasti K, Liu Y, Liu H, Zhang R, Chalak L 2021 Sep Pediatric Neurology 122 7-14

Acetaminophen and the developing brain: A critical review of the evidence

Angelis D, Chalak L 2021 Aug Early Human Development 159

Placental contribution to neonatal encephalopathy

Author Collaboration NB, Penn AA, Wintermark P, Chalak LF, Armstrong J, Redline R, Scher MS, Nelson KB 2021 Aug Seminars in Fetal and Neonatal Medicine 26

Part I. Mechanisms of actions and metabolism of acetaminophen related to the neonatal brain

Angelis D, Savani RC, Jagarapu J, Hu J, Wan-Huen P, Chalak L 2021 Aug Early Human Development 159

Part III. Neuronal biochemical effects of acetaminophen and neurodevelopmental outcomes: Friend or foe?

Angelis D, León RL, Chalak L 2021 Aug Early Human Development 159

Extremely Preterm Infant Admissions Within the SafeBoosC-III Consortium During the COVID-19 Lockdown

Rasmussen MI, Hansen ML, Pichler G, Dempsey E, Pellicer A, EL-Khuffash A, A S, Piris-Borregas S, Alsina M, Cetinkaya M, Chalak L, Özkan H, Baserga M, Sirc J, Fuchs H, Ergenekon E, Arruza L, Mathur A, Stocker M, Otero Vaccarello O, Szczapa T, Sarafidis K, Królak-Olejnik B, Memisoglu A, Reigstad H, Rafińska-Ważny E, Hatzidaki E, Peng Z, Gkentzi D, Viellevoye R, De Buyst J, Mastretta E, Wang P, Hahn GH, Bender L, Cornette L, Tkaczyk J, del Rio R, Fumagalli M, Papathoma E, Wilinska M, Naulaers G, Sadowska-Krawczenko I, Lecart C, Couce ML, Fredly S, Heuchan AM, Karen T, Greisen G 2021 Jul Frontiers in Pediatrics 9

Autism spectrum disorders in extremely preterm infants and placental pathology findings: a matched case–control study

Mir IN, White SP, Steven Brown L, Heyne R, Rosenfeld CR, Chalak LF 2021 May Pediatric Research 89 1825-1831

Historical perspectives for therapeutic hypothermia in the newborn: a life worth saving

Chalak L 2021 Apr Pediatric Research 89 1057-1058

The cerebellum’s role in neonatal brain injury

Chalak L 2021 Apr Pediatric Research 89 1055-1056

Nitric oxide and the brain. Part 2: Effects following neonatal brain injury—friend or foe?

Angelis D, Savani R, Chalak L 2021 Mar Pediatric Research 89 746-752

MRI Score Ability to Detect Abnormalities in Mild Hypoxic-Ischemic Encephalopathy

Machie M, Weeke L, de Vries LS, Rollins NK, Brown L, Chalak L 2021 Mar Pediatric Neurology 116 32-38

Limitations of Conventional Magnetic Resonance Imaging as a Predictor of Death or Disability Following Neonatal Hypoxic–Ischemic Encephalopathy in the Late Hypothermia Trial

Author Collaboration EK, Laptook AR, Shankaran S, Barnes P, Rollins N, Do BT, Parikh NA, Hamrick S, Hintz SR, Tyson JE, Bell EF, Ambalavanan N, Goldberg RN, Pappas A, Huitema C, Pedroza C, Chaudhary AS, Hensman AM, Das A, Wyckoff M, Khan A, Walsh MC, Watterberg KL, Faix R, Truog W, Guillet R, Sokol GM, Poindexter BB, Higgins RD, Caplan MS, Polin RA, Keszler M, Oh W, Vohr BR, McGowan EC, Alksninis B, Basso K, Bliss J, Bishop C, Burke RT, Cashore W, Caskey M, Gingras D, Guerina N, Johnson K, Keszler ML, Knoll AM, Sánchez PJ, Brion LP, Chalak LF, Heyne RJ 2021 Mar Journal of Pediatrics 230 106-111.e6

Regional heterogeneity of cerebral hemodynamics in mild neonatal encephalopathy measured with multichannel near-infrared spectroscopy

Tian F, Sepulveda P, Kota S, Liu Y, Das Y, Liu H, Zhang R, Chalak L 2021 Mar Pediatric Research 89 882-888

Vulnerable child syndrome in the neonatal intensive care unit: A review and a new preventative intervention with feasibility and parental satisfaction data

Hoge MK, Heyne E, Nicholson TD, Acosta D, Mir I, Brown LS, Shaw RJ, Chalak L, Heyne R 2021 Mar Early Human Development 154

Nitric oxide and the brain. Part 1: Mechanisms of regulation, transport and effects on the developing brain

Angelis D, Savani R, Chalak L 2021 Mar Pediatric Research 89 738-745

Placental origins of neonatal diseases: toward a precision medicine approach

Mir IN, Leon R, Chalak LF 2021 Jan Pediatric Research 89 377-383

Wavelet-based neurovascular coupling can predict brain abnormalities in neonatal encephalopathy

Das Y, Leon RL, Liu H, Kota S, Liu Y, Wang X, Zhang R, Chalak LF 2021 Jan NeuroImage: Clinical 32

Rigor of Neurovascular Coupling (NVC) Assessment in Newborns Using Different Amplitude EEG Algorithms

Das Y, Liu H, Tian F, Kota S, Zhang R, Chalak LF 2020 Dec Scientific reports 10

Cerebral Oxygenation and Autoregulation in Preterm Infants (Early NIRS Study)

Chock VY, Kwon SH, Ambalavanan N, Batton B, Nelin LD, Chalak LF, Tian L, Van Meurs KP 2020 Dec Journal of Pediatrics 227 94-100.e1

Diffusion-MRI-based regional cortical microstructure at birth for predicting neurodevelopmental outcomes of 2-year-olds

Ouyang M, Peng Q, Jeon T, Heyne R, Chalak L, Huang H 2020 Dec eLife 9 1-20

Statistical rigor and kappa considerations: which, when and clinical context matters

Chalak LF, Pavageau L, Huet B, Hynan L 2020 Jul Pediatric Research 88 5

Placental Pathology, Cerebral Blood Flow, and Intraventricular Hemorrhage in Preterm Infants: Is There a Link?

Pazandak C, Mir IN, Brown LS, Chalak LF 2020 Jul Pediatric Neurology 108 65-69

Impact of multiple placental pathologies on neonatal death, bronchopulmonary dysplasia, and neurodevelopmental impairment in preterm infants

Mir IN, Chalak LF, Brown LS, Johnson-Welch S, Heyne R, Rosenfeld CR, Kapadia VS 2020 Apr Pediatric Research 87 885-891

Inter-rater reliability of the modified Sarnat examination in preterm infants at 32–36 weeks’ gestation

Pavageau L, Sánchez PJ, Steven Brown L, Chalak LF 2020 Mar Pediatric Research 87 697-702

The rewards of peer-reviewing

Bearer CF, Chalak L, Fuentes-Afflick E, Molloy EJ 2020 Jan Pediatric Research 87 2

Regional heterogeneity of cerebral hemodynamics in neonatal hypoxic-ischemic encephalopathy

Tian F, Sepulveda P, Liu Y, Das Y, Liu H, Zhang R, Chalak L 2020

Neurovascular Coupling (NVC) in Newborns based on regional cerebral tissue oxygenation and amplitude EEG

Das Y, Liu H, Tian F, Liu YL, Kota S, Zhang R, Chalak LF 2020

A 20 years conundrum of neonatal encephalopathy and hypoxic ischemic encephalopathy: are we closer to a consensus guideline?

Chalak L, Ferriero DM, Gressens P, Molloy E, Bearer C 2019 Nov Pediatric Research 86 548-549

A Total Sarnat Score in Mild Hypoxic-ischemic Encephalopathy Can Detect Infants at Higher Risk of Disability

Chalak LF, Adams-Huet B, Sant'Anna G 2019 Nov Journal of Pediatrics 214 217-221.e1

Placental clearance/synthesis of neurobiomarkers GFAP and UCH-L1 in healthy term neonates and those with moderate–severe neonatal encephalopathy

Mir IN, Steven Brown L, Rosenfeld CR, Chalak LF 2019 Oct Pediatric Research 86 500-504

Development and Emergence of Individual Variability in the Functional Connectivity Architecture of the Preterm Human Brain

Xu Y, Cao M, Liao X, Xia M, Wang X, Jeon T, Ouyang M, Chalak L, Rollins N, Huang H, He Y 2019 Sep Cerebral Cortex 29 4208-4222

Quantitative end-tidal CO2 can predict increase in heart rate during infant cardiopulmonary resuscitation

Stine CN, Koch J, Brown LS, Chalak L, Kapadia V, Wyckoff MH 2019 Jun Heliyon 5

Should therapeutic hypothermia be offered to babies with mild neonatal encephalopathy in the first 6 h after birth?

El-Dib M, Inder TE, Chalak LF, Massaro AN, Thoresen M, Gunn AJ 2019 Mar Pediatric Research 85 442-448

Structural network maturation of the preterm human brain

Zhao T, Mishra V, Jeon T, Ouyang M, Peng Q, Chalak L, Wisnowski JL, Heyne R, Rollins N, Shu N, Huang H 2019 Jan NeuroImage 185 699-710

Age-specific gray and white matter DTI atlas for human brain at 33, 36 and 39 postmenstrual weeks

Feng L, Li H, Oishi K, Mishra V, Song L, Peng Q, Ouyang M, Wang J, Slinger M, Jeon T, Lee L, Heyne R, Chalak L, Peng Y, Liu S, Huang H 2019 Jan NeuroImage 185 685-698

Differential cortical microstructural maturation in the preterm human brain with diffusion kurtosis and tensor imaging

Ouyang M, Jeon T, Sotiras A, Peng Q, Mishra V, Halovanic C, Chen M, Chalak L, Rollins N, Roberts TP, Davatzikos C, Huang H 2019 Proceedings of the National Academy of Sciences of the United States of America 116 4681-4688

Prospective research in infants with mild encephalopathy identified in the first six hours of life: neurodevelopmental outcomes at 18–22 months

Chalak LF, Nguyen KA, Prempunpong C, Heyne R, Thayyil S, Shankaran S, Laptook AR, Rollins N, Pappas A, Koclas L, Shah B, Montaldo P, Techasaensiri B, Sánchez PJ, Sant’Anna G 2018 Dec Pediatric Research 84 861-868

Brain imaging in preterm infants <32 weeks gestation: a clinical review and algorithm for the use of cranial ultrasound and qualitative brain MRI

Ibrahim J, Mir I, Chalak L 2018 Dec Pediatric Research 84 799-806

Lenticulostriate vasculopathy in preterm infants: a new classification, clinical associations and neurodevelopmental outcome

Sisman J, Chalak L, Heyne R, Pritchard M, Weakley D, Brown LS, Rosenfeld CR 2018 Oct Journal of Perinatology 38 1370-1378

Fetal-placental crosstalk occurs through fetal cytokine synthesis and placental clearance

Mir IN, Chalak LF, Liao J, Johnson-Welch S, Brown LS, Longoria C, Savani RC, Rosenfeld CR 2018 Sep Placenta 69 1-8

A review of the conundrum of mild hypoxic-ischemic encephalopathy: Current challenges and moving forward

Chalak L, Latremouille S, Mir I, Sánchez PJ, Sant'Anna G 2018 May Early Human Development 120 88-94

Best practice guidelines on management of mild neonatal encephalopathy: Is it really mild?

Chalak LF 2018 May Early Human Development 120 74

Effect of Therapeutic Hypothermia Initiated after 6 Hours of Age on Death or Disability among Newborns with Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial

Author Collaboration ft, Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, Parikh NA, Ambalavanan N, Pedroza C, Pappas A, Das A, Chaudhary AS, Ehrenkranz RA, Hensman AM, Van Meurs KP, Chalak LF, Hamrick SE, Sokol GM, Walsh MC, Poindexter BB, Faix RG, Watterberg KL, Frantz ID, Guillet R, Devaskar U, Truog WE, Chock VY, Wyckoff MH, McGowan EC, Carlton DP, Harmon HM, Brumbaugh JE, Cotten CM, Sánchez PJ, Hibbs AM, Higgins RD 2018 Mar Obstetrical and Gynecological Survey 73 141-143

Prospective research on infants with mild encephalopathy: The PRIME study

Prempunpong C, Chalak LF, Garfinkle J, Shah B, Kalra V, Rollins N, Boyle R, Nguyen KA, Mir I, Pappas A, Montaldo P, Thayyil S, Sánchez PJ, Shankaran S, Laptook AR, Sant'anna G 2018 Jan Journal of Perinatology 38 80-85

Future alternative therapies in the pipeline for mild neonatal encephalopathy: Review of evidence of neuroprotection with erythropoiesis stimulating agents

DuPont T, Chalak L 2018 Jan Early Human Development

Effect of therapeutic hypothermia initiated after 6 hours of age on death or disability among newborns with hypoxic-ischemic encephalopathy a randomized clinical trial

Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, Parikh NA, Ambalavanan N, Pedroza C, Pappas A, Das A, Chaudhary AS, Ehrenkranz RA, Hensman AM, Van Meurs KP, Chalak LF, Hamrick SE, Sokol GM, Walsh MC, Poindexter BB, Faix RG, Watterberg KL, Frantz ID, Guillet R, Devaskar U, Truog WE, Chock VY, Wyckoff MH, McGowan EC, Carlton DP, Harmon HM, Brumbaugh JE, Cotten CM, Sánchez PJ, Hibbs AM, Higgins RD 2017 Oct JAMA - Journal of the American Medical Association 318 1550-1560

Impairment of cerebral autoregulation in pediatric extracorporeal membrane oxygenation associated with neuroimaging abnormalities

Tian F, Morriss MC, Chalak L, Venkataraman R, Ahn C, Liu H, Raman L 2017 Oct Neurophotonics 4

Effect of depth and duration of cooling on death or disability at age 18 months among neonates with hypoxic-ischemic encephalopathy a randomized clinical trial

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Huitema CM, Grisby C, Devaskar U, Ehrenkranz RA, Harmon HM, Chalak LF, DeMauro SB, Garg M, Hartley-McAndrew ME, Khan AM, Walsh MC, Ambalavanan N, Brumbaugh JE, Watterberg KL, Shepherd EG, Hamrick SE, Barks J, Michael Cotton C, Kilbride HW, Higgins RD 2017 Jul JAMA - Journal of the American Medical Association 318 57-67

New Wavelet Neurovascular Bundle for Bedside Evaluation of Cerebral Autoregulation and Neurovascular Coupling in Newborns with Hypoxic-Ischemic Encephalopathy

Chalak LF, Zhang R 2017 Jul Developmental Neuroscience 39 89-96

Novel Wavelet Real Time Analysis of Neurovascular Coupling in Neonatal Encephalopathy

Chalak LF, Tian F, Adams-Huet B, Vasil D, Laptook A, Tarumi T, Zhang R 2017 Apr Scientific reports 7

Early development of functional network segregation revealed by connectomic analysis of the preterm human brain

Cao M, He Y, Dai Z, Liao X, Jeon T, Ouyang M, Chalak L, Bi Y, Rollins N, Dong Q, Huang H 2017 Mar Cerebral Cortex 27 1949-1963

Heterogeneous increases of regional cerebral blood flow during preterm brain development: Preliminary assessment with pseudo-continuous arterial spin labeled perfusion MRI

Ouyang M, Jeon T, Roberts TP, Huang H, Ouyang M, Liu P, Jeon T, Lu H, Huang H, Ouyang M, Jeon T, Liu P, Lu H, Chalak L, Heyne R, Rollins NK, Licht DJ, Detre JA, Detre JA, Roberts TP, Huang H 2017 Feb NeuroImage 147 233-242

Hypothermia for neonatal hypoxic–ischemic encephalopathy: NICHD Neonatal Research Network contribution to the field

Shankaran S, Natarajan G, Chalak L, Pappas A, McDonald SA, Laptook AR 2016 Oct Seminars in Perinatology 40 385-390

Structural Development of Human Fetal and Preterm Brain Cortical Plate Based on Population-Averaged Templates

Yu Q, Ouyang A, Chalak L, Jeon T, Chia J, Mishra V, Sivarajan M, Jackson G, Rollins N, Liu S, Huang H 2016 Oct Cerebral Cortex 26 4381-4391

Inflammatory Biomarkers of Birth Asphyxia

Chalak LF 2016 Sep Clinics in Perinatology 43 501-510

Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: An example of a neonatal cooling trial

Author Collaboration EK, Pedroza C, Tyson JE, Das A, Laptook A, Bell EF, Shankaran S, Keszler M, Hensman AM, Vierira E, Little E, Shah B, Guerina N, Bliss J, Mirza H, Sommers R, Walsh MC, Hibbs AM, Newman NS, Siner BS, Zadell A, Truog WE, Pallotto EK, Kilbride HW, Gauldin C, Holmes A, Johnson K, Schibler K, Kallapur SG, Alexander B, Fischer EE, Gratton TL, Grisby C, Jackson L, Jennings J, Kirker K, Muthig G, Wuertz S, Michael Cotten C, Goldberg RN, Finkle J, Fisher KA, Grimes S, Laughon MM, Bose CL, Bernhardt J, Sánchez PJ, Stoll BJ, Wyckoff M, Chalak LF, Brion LP 2016 Jul Trials 17

Assessment of dynamic cerebral autoregulation in neonatal hypoxic-ischemic encephalopathy based on wavelet transform coherence

Tian F, Tarumi T, Liu H, Zhang R, Chalak L 2016 Apr

Assessment of dynamic cerebral autoregulation in neonatal hypoxic-ischemic encephalopathy based on wavelet transform coherence

Tian F, Tarumi T, Liu H, Zhang R, Chalak L 2016 Apr

Assessment of dynamic cerebral autoregulation in neonatal hypoxic- ischemic encephalopathy based on wavelet transform coherence

Tian F, Tarumi T, Liu H, Zhang R, Chalak L 2016 Apr 3

The impact of ambient operating room temperature on neonatal and maternal hypothermia and associated morbidities: A randomized controlled trial

Duryea EL, Nelson DB, Wyckoff MH, Grant EN, Tao W, Sadana N, Chalak LF, McIntire DD, Leveno KJ 2016 Apr American journal of obstetrics and gynecology 214 505.e1-505.e7

T1 and T2 values of human neonatal blood at 3 Tesla: Dependence on hematocrit, oxygenation, and temperature

Liu P, Chalak LF, Krishnamurthy LC, Mir I, Peng Sl, Huang H, Lu H 2016 Apr Magnetic resonance in medicine 75 1730-1735

Cerebral Hemodynamics in Asphyxiated Newborns Undergoing Hypothermia Therapy: Pilot Findings Using a Multiple-Time-Scale Analysis

Chalak LF, Tian F, Tarumi T, Zhang R 2016 Feb Pediatric Neurology 55 30-36

Assessment of dynamic cerebral autoregulation in neonatal hypoxic-ischemic encephalopathy based on wavelet transform coherence

Tian F, Tarumi T, Liu H, Zhang R, Chalak L 2016

Perinatal asphyxia in the delivery room: Initial management and current cooling guidelines

Chalak LF 2016 NeoReviews 17 e463-e470

Wavelet coherence analysis of dynamic cerebral autoregulation in neonatal hypoxic-ischemic encephalopathy

Tian F, Tarumi T, Liu H, Zhang R, Chalak L 2016 NeuroImage: Clinical 11 124-132

Is preeclampsia associated with fetal malformation? A review and report of original research

Nelson DB, Chalak LF, McIntire DD, Leveno KJ 2015 Dec Journal of Maternal-Fetal and Neonatal Medicine 28 2135-2140

Serial aEEG recordings in a cohort of extremely preterm infants: Feasibility and safety

Davis AS, Gantz MG, Do B, Shankaran S, Hamrick SE, Kennedy KA, Tyson JE, Chalak LF, Laptook AR, Goldstein RF, Hintz SR, Das A, Higgins RD, Ball MB, Hale EC, Van Meurs KP 2015 May Journal of Perinatology 35 373-378

Development of human brain structural networks through infancy and childhood

Huang H, Shu N, Mishra V, Jeon T, Chalak L, Wang ZJ, Rollins N, Gong G, Cheng H, Peng Y, Dong Q, He Y 2015 May Cerebral Cortex 25 1389-1404

Effect of depth and duration of cooling on deaths in the NICU among Neonates with hypoxic ischemic encephalopathy: A randomized clinical trial

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Meurs KP, Grisby C, Huitema CM, Garg M, Ehrenkranz RA, Shepherd EG, Chalak LF, Hamrick SE, Khan AM, Reynolds AM, Laughon MM, Truog WE, Dysart KC, Carlo WA, Walsh MC, Watterberg KL, Higgins RD 2015 Apr Obstetrical and Gynecological Survey 70 235-238

Placental pathology is associated with severity of neonatal encephalopathy and adverse developmental outcomes following hypothermia Presented in poster format at the annual meeting of the Pediatric Academic Societies, Vancouver, British Columbia, Canada, May 3-6, 2014.

Mir IN, Johnson-Welch SF, Nelson DB, Brown LS, Rosenfeld CR, Chalak LF 2015 American journal of obstetrics and gynecology 213 849.e1-849.e7

Structural development of human brain white matter from mid-fetal to perinatal stage

Ouyang A, Yu Q, Mishra V, Chalak L, Jeon T, Sivarajan M, Jackson G, Rollins N, Liu S, Huang H 2015

Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy a randomized clinical trial

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Grisby C, Huitema CM, Garg M, Ehrenkranz RA, Shepherd EG, Chalak LF, Hamrick SE, Khan AM, Reynolds AM, Laughon MM, Truog WE, Dysart KC, Carlo WA, Walsh MC, Watterberg KL, Higgins RD, Caplan MS, Polin RA, Keszler M, Vohr BR, Hensman AM, Vierira E, Little E, Sommers R, Shah B, Guerina N, McKinley LT, Caskey M, Halbrook A, Burke RT, Hibbs AM, Newman NS, Pallotto EK, Kilbride HW, Gauldin C, Holmes A, Johnson K, Kallapur SG, Alexander B, Fischer EE, Gratton TL, Jackson L, Jennings J, Kirker K, Muthig G, Wuertz S, Goldberg RN, Finkle J, Fisher KA, Grimes S, Bose CL, Bernhardt J, Clark C, Stoll BJ, Carlton DP, Hale EC, Loggins Y, Archer SW, Sokol GM, Wilson LD, Herron DE, Gunn S, Smiley L, Jadcherla SR, Sánchez PJ, Luzader P, Fortney CA, Besner GE, Parikh NA, Wallace D, Zaterka-Baxter KM, Crawford M, Gabrio J, Gantz MG, Newman JE, Auman JO, Nolen TL, Stevenson DK, Ball MB, Adams MM, Davis AS, Kibler C, Parker JR, Proud MS, Wong RJ, Ambalavanan N, Collins MV, Cosby SS, Devaskar U, Chanlaw T, Geller R, Ellsbury DL, Colaizy TT, Brumbaugh JE, Johnson KJ, Campbell DB, Walker JR, Klein JM, Segar JL, Dagle JM, Lindower JB, McElroy SJ, Rabe GK, Roghair RD, Meyer LR, Murphy CR, Bhavsar V, Ohls RK, Lacy CB, Beauman S, Hartenberger C, Schmidt B, Kirpalani H, De Mauro SB, Chaudhary AS, Abbasi S, Mancini T, Cucinotta DM, Laroia N, D'Angio CT, Guillet R, Lakshminrusimha S, Wynn K, Wadkins HI, Scorsone AM, Conway P, Sacilowski MG, Guilford S, Williams A, Wyckoff M, Brion LP, Vasil DM, Chen L, Ramon E, Kennedy KA, McDavid GE, Arldt-McAlister J, Burson K, Garcia C, Martin K, Rodgers S, Tate PL, Wright SL, Sood BG, Barks J, Batts M, De Jesus L, Hayes-Hart K, Johnson ME, Natarajan G, Sulkowski L, Sumner L, Walker N, Weingarden K, Christensen M, Wiggins SA, Gleason CA, Boyle RJ, Clemons T, D'Alton ME, Redmond CK, Ross MG, Weiner SJ, Willinger M 2014 Dec JAMA - Journal of the American Medical Association 312 2629-2639

Obstetric antecedents to body-cooling treatment of the newborn infant

Nelson DB, Lucke AM, McIntire DD, Sánchez PJ, Leveno KJ, Chalak LF 2014 Aug American journal of obstetrics and gynecology 211 155.e1-155.e6

Neurodevelopmental outcomes after hypothermia therapy in the era of Bayley-III

Chalak LF, Dupont TL, Sánchez PJ, Lucke A, Heyne RJ, Morriss MC, Rollins NK 2014 Aug Journal of Perinatology 34 629-633

Assessment of dynamic cerebral autoregulation in neonatal hypoxic-ischemic encephalopathy based on wavelet transform coherence

Tian F, Tarumi T, Liu H, Zhang R, Chalak L 2014 Jul

Predictive value of neonatal MRI showing no or minor degrees of brain injury after hypothermia

Rollins N, Booth T, Morriss MC, Sanchez P, Heyne R, Chalak L 2014 May Pediatric Neurology 50 447-451

Quantitative assessment of global cerebral metabolic rate of oxygen (CMRO2) in neonates using MRI

Liu P, Huang H, Rollins N, Chalak LF, Jeon T, Halovanic C, Lu H 2014 Mar NMR in biomedicine 27 332-340

Biomarkers for severity of neonatal hypoxic-ischemic encephalopathy and outcomes in newborns receiving hypothermia therapy

Chalak LF, Sánchez PJ, Adams-Huet B, Laptook AR, Heyne RJ, Rosenfeld CR 2014 Mar Journal of Pediatrics 164 468-474.e1

Serum biomarkers to evaluate the integrity of the neurovascular unit

Mir IN, Chalak LF 2014 Early Human Development 90 707-711

Non-invasive assessment of neonatal brain oxygen metabolism: A review of newly available techniques

Liu P, Chalak LF, Lu H 2014 Early Human Development 90 695-701

The "neurovascular unit approach" to evaluate mechanisms of dysfunctional autoregulation in asphyxiated newborns in the era of hypothermia therapy

Chalak LF, Tarumi T, Zhang R 2014 Early Human Development 90 687-694

A "neurovascular unit" approach in newborns with HIE: Can we improve outcomes?

Chalak LF 2014 Early Human Development 90 685

Resuscitation of preterm neonates with limited versus high oxygen strategy

Kapadia VS, Chalak LF, Sparks JE, Allen JR, Savani RC, Wyckoff MH 2013 Dec Pediatrics 132 e1488-e1496

Change in care among nonenrolled patients during and after a randomized trial

LeVan JM, Wyckoff MH, Ahn C, Heyne R, Sánchez PJ, Chalak L, Jaleel MA, Jeannette Burchfield P, Christie L, Soll R, Badger GJ, Brion LP 2013 Oct Pediatrics 132 e960-e970

Perinatal asphyxia with hyperoxemia within the first hour of life is associated with moderate to severe hypoxic-ischemic encephalopathy

Kapadia VS, Chalak LF, Dupont TL, Rollins NK, Brion LP, Wyckoff MH 2013 Oct Journal of Pediatrics 163 949-954

Short-term outcomes of newborns with perinatal acidemia who are not eligible for systemic hypothermia therapy

Dupont TL, Chalak LF, Morriss MC, Burchfield PJ, Christie L, Sánchez PJ 2013 Jan Journal of Pediatrics 162 35-41

Perinatal acidosis and hypoxic-ischemic encephalopathy in preterm infants of 33 to 35 weeks' gestation

Chalak LF, Rollins N, Morriss MC, Brion LP, Heyne R, Sánchez PJ 2012 Mar Journal of Pediatrics 160 388-394

Neuroprotective approaches: Before and after delivery

Chalak LF, Rouse DJ 2011 Sep Clinics in Perinatology 38 455-470

Low-voltage aEEG as predictor of intracranial hemorrhage in preterm infants

Chalak LF, Sikes NC, Mason MJ, Kaiser JR 2011 May Pediatric Neurology 44 364-369

End-Tidal CO2 detection of an audible heart rate during neonatal cardiopulmonary resuscitation after asystole in asphyxiated piglets

Chalak LF, Barber CA, Hynan L, Garcia D, Christie L, Wyckoff MH 2011 May Pediatric Research 69 401-405

Immediate pro-inflammatory cytokine response associated with asphyxia and volume infusions in a neonatal piglet model

Chalak LF, Laptook AR, Perlman JM, Garcia D, Ramilo O, Wyckoff MH 2008 Journal of Neonatal-Perinatal Medicine 1 69-75

Neonatal guideline hypoxic-ischemic encephalopathy (HIE).

Chalak L, Kaiser J 2007 Oct The Journal of the Arkansas Medical Society 104 87-89

A newborn with Poland anomaly and liver ectopy: An unusual association with important prognostic implications

Chalak LF, Parham DM 2007 Mar Pediatric and Developmental Pathology 10 134-137

Resolution of pulmonary interstitial emphysema following selective left main stem intubation in a premature newborn: An old procedure revisited

Chalak LF, Kaiser JR, Arrington RW 2007 Feb Paediatric anaesthesia 17 183-186

Chorioamnionitis and neonatal encephalopathy in term infants with fetal acidemia: Histopathologic correlations

Shalak L, Johnson-Welch S, Perlman JM 2005 Sep Pediatric Neurology 33 162-165

Depression at birth in term infants exposed to maternal chorioamnionitis: Does neonatal fever play a role?

Shalak LF, Perlman JM, Jackson GL, Laptook AR 2005 Jul Journal of Perinatology 25 447-452

Erratum: Stages of status epilepticus in the developing brain (Epilepsy Research (2003) 55 (9-19) DOI: 10.1016/S0920-1211(03)00089-5)

Mikati MA, Werner S, Shalak L, Shamseddine A, Simaan E, Liu Z, Tarif S, Stafstrom C, Holmes G 2005 Feb Epilepsy Research 63 157

Erratum: Stages of status epilepticus in the developing brain (Epilepsy Research (2003) 55 (9-19) DOI: 10.1016/S0920-1211(03)00089-5)

Mikati MA, Werner S, Shalak L, Shamseddine A, Simaan E, Liu Z, Tarif S, Stafstrom C, Holmes G 2005 Feb Epilepsy Research 63 157

Hypoxic-ischemic brain injury in the term infant-current concepts

Shalak L, Perlman JM 2004 Nov Early Human Development 80 125-141

Chorioamnionitis, cytokines, and brain injury [5] (multiple letters)

Freeman JM, Shalak LF, Laptook AR, Perlman JM 2003 Jul Pediatrics 112 206-207

Amplitude-integrated electroencephalography coupled with an early neurologic examination enhances prediction of term infants at risk for persistent encephalopathy

Shalak LF, Laptook AR, Velaphi SC, Perlman JM 2003 Feb Pediatrics 111 351-357

Stages of status epilepticus in the developing brain

Mikati MA, Werner S, Shehab L, Shamseddine A, Simaan E, Liu Z, Tarif S, Stafstrom C, Holmes G 2003 Epilepsy Research 55 9-19

Hemorrhagic-ischemic cerebral injury in the preterm infant: Current concepts

Shalak L, Perlman JM 2002 Dec Clinics in Perinatology 29 745-763

Clinical chorioamnionitis, elevated cytokines, and brain injury in term infants

Shalak LF, Laptook AR, Jafri HS, Ramilo O, Perlman JM 2002 Oct Pediatrics 110 673-680

Complete cleft sternum and congenital heart disease: Review of the literature

Shalak L, Kaddoura I, Obeid M, Hashem H, Haidar R, Bitar FF 2002 Pediatrics International 44 314-316

Infection markers and early signs of neonatal encephalopathy in the term infant

Shalak LF, Perlman JM 2002 Mental Retardation and Developmental Disabilities Research Reviews 8 14-19

Differences in brain temperature and cerebral blood flow during selective head versus whole-body cooling

Laptook AR, Shalak L, Corbett RJ 2001 Pediatrics 108 1103-1110