People

Originally from Fukuoka, Japan, Dr. Yoshi Muto earned his M.D. and Ph.D. degrees at Kyushu University. He completed his internal medicine residency and nephrology fellowship training at Iizuka Hospital before pursuing postdoctoral research in nephrology at Washington University in St. Louis. Following his postdoctoral training, he served as an Instructor at Washington University before joining the UT Southwestern faculty in 2024.

Dr. Muto’s research focuses on epigenetic and metabolic mechanisms driving kidney disease progression, with a particular emphasis on (1) Acute kidney injury and its transition to chronic kidney disease, (2) Autosomal dominant polycystic kidney disease (ADPKD). His work explores how metabolic dysregulation alters the epigenome in kidney diseases, aiming to uncover novel therapeutic targets. By integrating mouse genetics, single-cell multi-omics, and cutting-edge genomic technologies, Dr. Muto and his team seek to unravel key regulatory networks in kidney injury and repair.