Publications

Featured Publications

Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.

Cruz VE, Sekulski K, Peddada N, Sailer C, Balasubramanian S, Weirich CS, Stengel F, Erzberger JP, 2022 Dec Nat Struct Mol Biol 12 29 1228-1238

A comprehensive landscape of 60S ribosome biogenesis factors.

Sailer C, Jansen J, Sekulski K, Cruz VE, Erzberger JP, Stengel F, 2022 02 Cell Rep 6 38 110353

rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly

Sekulski K, Cruz VE, Weirich, CS, Erzberger JP 2022

Structure of a yeast 40S-eIF1-eIF1A-eIF3-eIF3j initiation complex.

Aylett CH, Boehringer D, Erzberger JP, Schaefer T, Ban N 2015 Mar Nat. Struct. Mol. Biol. 3 22 269-71

Architecture of the large subunit of the mammalian mitochondrial ribosome.

Greber BJ, Boehringer D, Leitner A, Bieri P, Voigts-Hoffmann F, Erzberger JP, Leibundgut M, Aebersold R, Ban N 2014 Jan Nature 7484 505 515-9

Molecular architecture of the 40S·eIF1·eIF3 translation initiation complex.

Erzberger JP, Stengel F, Pellarin R, Zhang S, Schaefer T, Aylett CH, Cimermancic P, Boehringer D, Sali A, Aebersold R, Ban N 2014 Aug Cell 5 158 1123-35

Nucleotide and partner-protein control of bacterial replicative helicase structure and function.

Strycharska MS, Arias-Palomo E, Lyubimov AY, Erzberger JP, O'Shea VL, Bustamante CJ, Berger JM 2013 Dec Mol. Cell 6 52 844-54

Structure of the C-terminus of the mRNA export factor Dbp5 reveals the interaction surface for the ATPase activator Gle1.

Dossani ZY, Weirich CS, Erzberger JP, Berger JM, Weis K 2009 Sep Proc. Natl. Acad. Sci. U.S.A. 38 106 16251-6

Structural synergy and molecular crosstalk between bacterial helicase loaders and replication initiators.

Mott ML, Erzberger JP, Coons MM, Berger JM 2008 Nov Cell 4 135 623-34

The septin family of GTPases: architecture and dynamics.

Weirich CS, Erzberger JP, Barral Y 2008 Jun Nat. Rev. Mol. Cell Biol. 6 9 478-89

Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export.

Weirich CS, Erzberger JP, Flick JS, Berger JM, Thorner J, Weis K 2006 Jul Nat. Cell Biol. 7 8 668-76

Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling.

Erzberger JP, Mott ML, Berger JM 2006 Aug Nat. Struct. Mol. Biol. 8 13 676-83

Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex.

Clarey MG, Erzberger JP, Grob P, Leschziner AE, Berger JM, Nogales E, Botchan M 2006 Aug Nat. Struct. Mol. Biol. 8 13 684-90

Evolutionary relationships and structural mechanisms of AAA+ proteins.

Erzberger JP, Berger JM 2006 Annu Rev Biophys Biomol Struct 35 93-114

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA.

Zhang R, Poustovoitov MV, Ye X, Santos HA, Chen W, Daganzo SM, Erzberger JP, Serebriiskii IG, Canutescu AA, Dunbrack RL, Pehrson JR, Berger JM, Kaufman PD, Adams PD 2005 Jan Dev. Cell 1 8 19-30

The N-terminal domain of Nup159 forms a beta-propeller that functions in mRNA export by tethering the helicase Dbp5 to the nuclear pore.

Weirich CS, Erzberger JP, Berger JM, Weis K 2004 Dec Mol. Cell 5 16 749-60

Structure and function of the conserved core of histone deposition protein Asf1.

Daganzo SM, Erzberger JP, Lam WM, Skordalakes E, Zhang R, Franco AA, Brill SJ, Adams PD, Berger JM, Kaufman PD 2003 Dec Curr. Biol. 24 13 2148-58

The structure of bacterial DnaA: implications for general mechanisms underlying DNA replication initiation.

Erzberger JP, Pirruccello MM, Berger JM 2002 Sep EMBO J. 18 21 4763-73

Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism.

Beernink PT, Segelke BW, Hadi MZ, Erzberger JP, Wilson DM, Rupp B 2001 Apr J. Mol. Biol. 4 307 1023-34

Mapping the protein-DNA interface and the metal-binding site of the major human apurinic/apyrimidinic endonuclease.

Nguyen LH, Barsky D, Erzberger JP, Wilson DM 2000 May J. Mol. Biol. 3 298 447-59

The human homolog of Escherichia coli Orn degrades small single-stranded RNA and DNA oligomers.

Nguyen LH, Erzberger JP, Root J, Wilson DM 2000 Aug J. Biol. Chem. 34 275 25900-6

The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

Erzberger JP, Wilson DM 1999 Jul J. Mol. Biol. 2 290 447-57

Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases.

Erzberger JP, Barsky D, Schärer OD, Colvin ME, Wilson DM 1998 Jun Nucleic Acids Res. 11 26 2771-8