Publications

Peer-reviewed Original Investigations (lead or corresponding author)

  1. Cellular profiling identifies targetable T cell phenotypes in lymphocytic variant hypereosinophilic syndrome. J Clin Invest. 2025 Nov 3;135(21):e190853. doi: 10.1172/JCI190853. PMID: 41178717; PMCID: PMC12578380.
  2. Addiction of primary cutaneous γδ T cell lymphomas to JAK/STAT signaling. J Clin Invest. 2025 Apr 15;135(8):e180417. doi: 10.1172/JCI180417. PMID: 40231467; PMCID: PMC11996904.
  3. Primary cutaneous cd8+ aggressive epidermotropic cytotoxic t-cell lymphoma with novel FGFR1 fusion treated with pemigatinib. Blood Adv. 2025 Apr 22;9(8):1786-1790. doi: 10.1182/bloodadvances.2024014928. PMID: 39825823; PMCID: PMC12008514. *Co-corresponding author
  4. Distinctive genomic features of HTLV-1 related adult T-cell leukemia-lymphoma in Western populations. Haematologica. 2024 Dec 1;109(12):4021-4039. PMID: 39113648. PMCID: PMC11609816. 
    *Co-corresponding author
  5. Pre-existing skin-resident CD8 and gd T cell circuits mediate immune response in Merkel cell carcinoma and predict immunotherapy efficacy. Cancer Discovery. 2024. Sep 4;14(9):1631-1652. PMID: 39058036. *Co-corresponding author
  6. Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus. Nature. 2024. Jul;631(8022):857-866. PMID: 38987586. *Co-corresponding author
  7. Naturally Occurring T cell mutations enhance engineered T cell therapies. Nature. 2024. Feb;626(7999):626-634. PMID: 38326614. *Co-corresponding author
  8. PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma. Nature Cancer. 2023 Oct;4(10):1508-1525. PMID: 37723306. PMCID: PMC10597841. *Co-corresponding author
  9. BACH2 is a putative T cell lymphoma tumor suppressor that may play a role in product-derived CAR-T cell lymphomas. Blood 2021 Dec 23;138(25):2731-2733. PMID: 34499707. *Co-corresponding author
  10. Primary Cytotoxic T Cell Lymphomas Harbor Recurrent Targetable Alterations in the JAK-STAT Pathway. Blood. 2021 Dec 9; 138(23):2435-2440. PMID: 34432866. *Co-corresponding author
    Featured in Blood Commentary. “Oncogenic fusions JAK up CD8+ cytotoxic CTCL.”
  11. ZEB1 Promotes Pathogenic Th1 and Th17 Cell Differentiation in Autoimmune Disease. Cell Reports. 2021 Aug. 38(8). PMID: 34433042. *Co-corresponding author
  12. Genomic Landscape of Cutaneous Follicular Lymphomas Reveal Two Subgroups with Clinically Predictive Molecular Features. Blood Advances. 2021 Feb. 5(3): 649-661. PMID: 33560380. *Co-corresponding author
  13. Integrated Genomic Analyses of Cutaneous T Cell Lymphomas Reveal the Molecular Bases for Disease Heterogeneity. Blood. 2021 Oct 7;138(14):1225-1236. PMID: 34115827. *Co-corresponding author
    Featured in Blood Commentary. “PD-1 loss and T cell exhaustion in CTCL tumoral T cells.”
  14. Cellular Origins and Genetic Landscape of Cutaneous Gamma Delta T Cell Lymphomas. Nature Communications. 2020 April. 11(1806). PMID: 32286303. *Corresponding author
    Named one of the Editor’s weekly highlights
  15. Genomic Analyses Identify Recurrent Alterations in Immune Evasion Genes in Diffuse Large B Cell Lymphoma, Leg Type. J Invest Dermatol. 2018 Nov; 138(11):2365-76. PMID: 29857068. *Corresponding author
  16. Functional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma. Cell Immunology. 2017 Sep;319:28-34. PMID: 28711152. *Co-corresponding author
  17. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. 2017 Sep 21;130(12):1430-1440. PMID: 28694326. *Corresponding author
    Featured in Inside Blood Commentary. “Expanding and expounding the genomic map of CTCL.”
  18. Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib. Journal of Invest Dermatol. 2017 Apr; 137(4): 951-954. PMID: 27887955. *Senior author
  19. Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome. Blood, 2016 Feb; 127(7):948-51. PMID: 26702067. *Corresponding author
  20. Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy. Oncotarget. 2016 Jan;7(3):3403-15. PMID: 26655088. PMCID: PMC4823115. 
    *Co-corresponding author. 
    Profiled by F1000
  21. Genomic landscape of cutaneous T cell lymphoma. Nat Genet. 2015 Sep;47(9):1011-9 PMID: 26192916.   
  22. Identification of PLX4032-Resistance Mechanisms and Implications for Novel RAF Inhibitors. Pigment Cell Melanoma Res. 2014 Mar; 27(2):253-262. PMID: 24283590. *Co-corresponding author.
  23. Endothelial cells promote HIV replication in nondividing memory T cells via Nef-, Vpr-, and T-cell receptor-dependent activation of NFAT.  J Virol. 2005 Sept;79(17):11194-204. PMID: 16103171.
  24. Human endothelial cells enhance human immunodeficiency virus type 1 replication in CD4+ T cells in a Nef-dependent manner in vitro and in vivo.  J Virol. 2005 Jan;79(1):264-76. PMID: 15596822. 

Invited Reviews and Commentaries

  1. Circulating tumor DNA level is associated with time to clinical recurrence in Merkel cell carcinoma: Implications for patient management. J Am Acad Dermatol. 2026 Feb;94(2):548-556. doi: 10.1016/j.jaad.2025.10.032. Epub 2025 Oct 10. PMID: 41077138; PMCID: PMC12596136.
  2. A phase-2 study of pembrolizumab in patients with biologically selected subtypes of relapsed/refractory aggressive lymphomas. Leuk Lymphoma. 2025 Jul;66(7):1354-1357. doi: 10.1080/10428194.2025.2478525. Epub 2025 Mar 25. PMID: 40134121.
  3. Inhibitory Co-Receptor LAG3 Supports Foxp3+ Regulatory T Cell Function by Restraining Myc-Dependent Metabolic Programming. Immunity. 2024 Nov 12;57(11):2634-2650.e5. PMID: 39236718.
  4. Circulating tumor DNA assay detects Merkel cell carcinoma recurrence, disease progression, and minimal residual disease: surveillance and prognostic implications. J Clin Oncol. 2024 Sep 10;42(26):3151-3161. PMID: 39052958. PMCID: PMC11379364.
  5. Single-cell Analysis Uncovers Striking Cellular Heterogeneity of Lung-Infiltrating Regulatory T Cells during Eosinophilic versus Neutrophilic Allergic Airway Inflammation. J Immunol. 2024 Jun 15;212(12):1867-1876. PMID: 38647384.
  6. Interstitial mycosis fungoides: A rare presentation of mycosis fungoides with overlapping granulomatous and folliculotropic features. J Cutan Pathol. 2024 Jun;51(6):459-467. PMID: 38443749.
  7. KLRG1 Cell Depletion As A Novel Therapeutic Strategy In Patients With Mature T-cell lymphoma Subtypes. Clinical Cancer Research. 2024 Jun 3;30(11):2514-2530. PMID: 38252421.
  8. Genetic Risk Factors for Early-Onset Merkel Cell Carcinoma. JAMA Dermatol. 2024 Feb1;160(2):172-178. PMID: 38170500.
  9. A single-cell atlas of IL-23 inhibition in cutaneous psoriasis distinguishes clinical response. Sci Immunol. 2024 Jan 26;9(92) Epub. PMID: 38277466.
  10. Lifestyle, demographic and Skindex measures associated with cutaneous T-cell lymphoma: a single institution cohort study. Arch Dermatol Res. 2023 Mar;315(2):275-278. PMID: 35668201.
  11. Retrospective analysis of sepsis in cutaneous T-cell lymphoma reveals significantly greater risk in Black patients. J Am Acad Dermatol. 2023 Feb;88(2):329-337. PMID: 36265823.
  12. The Robust Tumoricidal Effects of Combined BET/HDAC Inhibition in CTCL Can be Reproduced by delta Np73 Depletion. J Invest Dermatol. 2022 Dec; 142(12):3253-3261. PMID: 35787399.
  13. Narrowband ultraviolet B response in cutaneous T-cell lymphoma is characterized by increased bacterial diversity and reduced Staphylococcus aureus and Staphylococcus lugdunensis. Front Immunol. 2022 Nov 11; 13:1022093. PMID: 36439132.
  14. Acceleration of Skin Involvement as a Predictor of Disease Progression in Early-Stage Mycosis Fungoides: A Retrospective Cohort Study. J Am Acad Dermatol. 2022 Nov;87(5):1140-1141. PMID: 35167923.
  15. Transcriptional and functional analyses of neoantigen-specific CD4 T cells during a profound response to anti-PD-L1 in metastatic Merkel cell carcinoma. J Immunother Cancer. 2022 Sep; 10(9):e005328. PMID: 36252564.
  16. Cutaneous T-Cell-Rich Lymphoid Infiltrates After SARS CoV-2 Vaccination. JAMA Dermatol. 2022 Sep 1;158(9):1073-1076. PMID 35857292.
  17. Gut dysbiosis in cutaneous T-cell lymphoma is characterized by shifts in relative abundances of specific bacterial taxa and decreased diversity in more advanced disease. J Eur Acad Dermatol Venerol. 2022 Sep;36(9):1552-1563. PMID: 35366365.
  18. A single-cell transcriptional gradient in human cutaneous memory T cells suppresses pathogenic Th17 inflammation. Cell Reports Medicine. 2022 Aug 16; 3(8):100715. PMID: 35977472.
  19. Differences in Merkel cell carcinoma survival by site of primary presentation. J Am Acad Dermatol. 2022 May;86(5):1120-1123. PMID: 33882278.
  20. Classification of human chronic inflammatory skin disease based on single-cell profiling. Science Immunology. 2022 Apr 15;7(70). PMID: 35427179.
  21. Scarring alopecia developing after mogamulizumab-associated rash. Eur J Dermatol. 2021 Dec 1;31(6):841-843. PMID: 35107074.
  22. Epigenetic Regulation of Apoptosis in Cutaneous T-cell Lymphoma: Implications for Therapy with Methotrexate, JAK Inhibitors, and Resveratrol. J Invest Dermatol. 2022 Feb;142(2):493-496. PMID: 34358529.
  23. Steroid responsiveness in Foxp3+ regulatory T cells determines steroid responsiveness in allergic airway inflammation in mice. J Immunol. Cutting Edge 2021 Aug. 207(3): 765-770. PMID: 34301840.
  24. Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation. iScience. 2020 Sep. 23(10):101582. PMID: 33205009. PMCID: PMC7648132.
  25. Progression of Cutaneous T-Cell Lymphoma after Dupilumab: Case Review of 7 Patients. J Am Acad Dermatol. 2020 Jul. 83(1):197-199. PMID: 32229275.
  26. Celastrol-loaded PEG-b-PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis. Biomater Sci. 2019 Jan 2. 7(2):657-668. PMID: 30601470.
  27. Hemophagocytic lymphohistiocytosis in cutaneous T cell lymphoma. JAMA Derm. 2018 Jul;154 (7):828-831. PMID: 29874360.
  28. Progression of undiagnosed cutaneous lymphoma after anti-tumor necrosis factor alpha therapy. J Am Acad Dermatol. 2018 Jun; 78(6):1068-1076. PMID: 29307643.
  29. Merkel cell carcinoma patients presenting without a primary lesion have elevated markers of immunity, higher tumor mutation burden and improved survival. Clin Cancer Res. 2018 Feb 15;24(4):963-971. PMID: 29246939.
  30. Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure. J Invest Dermatol. 2018 Feb;138(2):384-393. PMID 28870692.
  31. CD8+ mycosis fungoides: A low-grade lymphoproliferative disorder. J Am Acad Dermatol. 2017 Sep; 77(3):489-496. PMID: 28676328.
  32. FISH panel for cutaneous T cell lymphoma. Journal of Invest Dermatol. 2017 Mar;137(3):751-753. PMID: 27836797.
  33. IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression. Neuro Oncol. 2016 Oct; 18(10):1402-12. PMID: 27116977.
  34. Non-overlapping Clinical and Mutational Patterns in Melanomas From the Female Genital Tract and Atypical Genital Nevi. J Invest Dermatol. 2016 Sep; 136(9):1858-65. PMID: 27220476.
  35. Telomere replication stress induced by POT1 inactivation accelerates tumorigenesis. Cell Rep. 2016 Jun 7;15(10):2170-84. PMID: 27239034.
  36. Cutaneous T cell lymphoma: current practices in blood assessment and the utility of the T-cell receptor Vb chain restriction. Journal of Amer Acad Dermatol., 2016 May; 74(5):870-7. PMID: 26874819.
  37. Defining the Polyposis/Colorectal Cancer Phenotype Associated with the Ashkenazi GREM1 Duplication: Counseling and Management Recommendations. Genet Res. 2016 Mar; 44(1):48-53. PMID: 27103854.
  38. Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma. Proc Natl Acad Sci., 2016 Feb; 113(8):2170-5. PMID: 26864202.
  39. A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT. J Cutan Pathol. 2015 Feb;42(2):108-17 PMID: 25407517.
  40. Activation of GILZ gene by photoactivated 8-methoxypsoralen: potential role of immunoregulatory dendritic cells in extracorporeal photochemotherapy. Transfus Apher Sci. 2014 Jun;50(3):379-387 PMID: 24215840.
  41. Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis. J Biol Chem. 2003 Jun 6;278(23):21295-306. PMID: 12663669. 

Invited Reviews and Commentaries

  1. Contemporary Management of Merkel Cell Carcinoma. Hematol Oncol Clin North Am. 2026 Feb;40(1):101-115. doi: 10.1016/j.hoc.2025.07.009. PMID: 41224435.
  2. T Peripheral Helper Cells in Lymphoid Aggregate and Tertiary Lymphoid Structure Formation. Immunol Rev. 2026 Jan;337(1):e70088. doi: 10.1111/imr.70088. PMID: 41424090.
  3. Brief Review: TCR Mutations in Mature T Cell Lymphomas. J Immunol. 2023 Nov 15;211(10):1450-1458. PMID: 37931208. *Corresponding author
  4. Disease-Defining Molecular Features of Primary Cutaneous B-Cell Lymphomas: Implications for Classification and Treatment. J Invest Dermatol. 2023 Feb;143(2):189-196. PMID: 36163302. PMCID: PMC10260375. *Corresponding author
  5. The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients with Glioblastoma. Frontiers in Pharmcology. 2019 Mar; PMID: 30971917.
  6. Are MicroRNAs Key to Developing Biomarkers for Cutaneous T-cell Lymphoma? J Invest Dermatol. 2018 Sep;138(9):1906-1908. PMID: 30143078. *Corresponding author
  7. Are there Multiple Cells of Origin of Merkel Cell Carcinoma. Oncogene. 2018 Mar;37(11):1409-1416. PMID: 29321666. *Corresponding author
    Featured in F1000Prime Article Recommendations
  8. Current landscape and future of dual anti-CTLA-4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC). J Immunother Cancer. 2018 May; 6(1):39. PMID: 29769148.
  9. Challenges and future of biomarker tests in the era of precision oncology: Can we rely on immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) to select the optimal patients for matched therapy? Oncotarget 2017 Aug 1; 8(59) 100863-100898. PMID: 29246028.
  10. Photopheresis for Scleroderma. Curr Rheumatol Rep. 2017 Jun; 19(6):31. PMID: 28466383. *Corresponding author
  11. Advancements in unresectable melanoma: a multidisciplinary perspective. Melanoma Management. 2016 Sep; 3(3):171-175. PMID: 30190886.
  12. Genetics of cutaneous T cell lymphoma: from bench to bedside. Curr Treat Options Oncol. 2016 Jul; 17(7):33. PMID: 2762707. *Corresponding author
  13. Cutaneous T cell lymphoma. Hematol Oncol Clin North Am. 2008 Oct;22(5):979-96. PMID: 18954747.
  14. Cutaneous T cell lymphoma: Biologic targets for therapy. Curr Hematol Malig Rep. 2007 Oct;2(4):272-277. PMID: 20425380.
  15. T lymphocyte-endothelial cell interactions. Annu Rev Immunol. 2004;22:683-709. PMID: 15032593. 

Books and Book Chapters

  1. Hematopoietic Stem Cell Transplantation: A Handbook for Clinicians, 2nd ed. Bethesda, MD: AABB Press, 2014.
  2. Extracorporeal Photochemotherapy. In: Wolverton eds., Comprehensive Drug Therapy, 3rd ed. China: Elsevier-Saunders, 2012.
  3. Apheresis: Principles and Practice 3rd ed. Bethesda, MD: AABB Press, 2010.
  4. Geriatrics Review Syllabus: A Core Curriculum in Geriatric Medicine th ed. New York, NY: American Geriatrics Society; 2008.

Case Reports, Letters, Editorials

  1. Partial remission of advanced untreated Sezary Syndrome after COVID-19. JAAD Case Reports. 2022 Mar;21:165-168. PMID: 35013712. *Corresponding author
  2. Pembrolizumab and pallitative radiotherapy in 2 cases of refractory mycosis fungoides. JAAD Case Reports. 2020 Nov 6;87-90. PMID: 33344742.
  3. Assessment of Age, Period, and Birth Cohort Effects and Trends in Merkel Cell Carcinoma Incidence in the United States. PracticeUpdate website. Accessed December 04, 2020.
  4. Factors Associated With Time to Treatment for Merkel Cell Carcinoma. PracticeUpdate website.  Accessed December 04, 2020.
  5. Drug induced hypersensitivity syndrome with myocardial involvement treated with tofacitinib. JAAD Case Reports. 2019 Nov 13;5(12):1018-1026. PMID: 31763425.
  6. A discordant cutaneous eruption in neonatal twins. JAMA Dermatol. 2016 Apr; 152(4):463-4. PMID: 26791600. *Corresponding author
  7. Rapidly enlarging nodular plaque on the leg. JAMA Dermatol. 2014 Aug 13. PMID: 25133474. *Corresponding author
  8. Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features. Int J Dermatol. 2011 Dec;50(12):1480-5.PMID: 22097993.
  9. Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia. Yale J Biol Med. 2006 Dec; 79(3-4):169-72. PMID: 17940627.