We are a diverse group of folks that care about understanding molecular mechanisms in normal and disease states
D'Orso Lab is associated with the Molecular Microbiology and Biochemistry and Cellular and Molecular Biology graduate programs. We are located in the Department of Microbiology and are associated with the Molecular Microbiology and Biochemistry / Cellular and Molecular Biology graduate programs. Our team is comprised of graduate students, postdocs, and research assistants. For more details please see Lab Projects or directly contact the Principal Investigator.
Meet the Principal Investigator
Ivan D'Orso, Ph.D.
The major theme of Dr. D'Orso's work is to characterize the mechanisms of HIV transcriptional regulation, and the molecular and structural basis of cellular reprogramming by viral transcription factors. His current work is focused on using cell biological, biochemical, and genetic studies to elaborate the contribution of these host co-factors to the establishment of latency and efforts for HIV eradication. Dr. D’Orso’s research program is supported by grants from the National Institutes of Health, The Welch Foundation, and an Institutional grant from the American Cancer Society.
Current Lab Members
(2017 – Present)
Ashwini is working towards completing a global comparative analysis of RNA polymerase II elongation complexes in eukaryotic cells.
Graduate Student I Genetics, Development & Disease Ph.D. Program
(2019 – Present)
Usman is working towards determining how the transcription elongation factor KAP1 recognizes chromatin at target gene promoters to exert transcription activation.
(2016 – Present)
Graduate Student I Molecular Microbiology
(2014 – Present)
Nora is interested in defining new pathways that control the establishment and maintenance of HIV proviral latency in CD4 T cells using an unbiased gain-of-function approach with human cDNAs.
Jinli Wang, Ph.D.
(2017 – Present)
Jinli is interested in elucidating how the ARF tumor suppressor cooperates with transcription elongation factors to control cell fate and prevent cancer development.
Ashutosh Shukla, Ph.D.
(2018 – Present)
Former Lab Members
Youn-Tae Kwak, Ph.D.
Current Position: Research Scientist, UT Southwestern
Swapna Aravind, Ph.D.
Current Position: Postdoctoral Researcher, Huntsman Cancer Center, Salt Lake City, Utah
Current Position: Graduate Student, University of Minnesota
Green Fellow, Research Associate
Current Position: Medical School, UT Southwestern
Ryan McNamara, Ph.D.
Graduate Student, Molecular Microbiology
Current Position: Postdoctoral Fellow in Dirk Dittmer's lab, UNC Chapel Hill
Current Position: Research Associate
Current Position: Research Associate, Peloton Therapeutics, Inc (Dallas, Texas)
Current Position: Graduate Student, Bioinformatics & Systems Biology, UC San Diego
Current Position: Data Analyst, TXU (Dallas, TX)
Graduate Student, Biological Chemistry
Current Position: Postdoctoral Fellow in Julia Zeitlinger’s lab at Stowers Institute, Kansas City
Zheng Ma. Ph.D.