Radhakrishnan Lab


We are interested in how membrane cholesterol controls diverse cellular signaling pathways to ensure lipid homeostasis, enable cell growth, and protect against infections.  More specifically, we seek to understand the mechanisms by which protein sensors measure membrane cholesterol and protein transporters move cholesterol between and across membranes. 

Our laboratory takes a multidisciplinary approach encompassing biochemistry, biophysics, and cell biology to understand cholesterol metabolism.

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