This is placeholder text about our research and our mission. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on.
This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on. This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on. This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on. This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on.
Optional sub-heading containing more definition of the content. (Plain text)
The Two-Column callout below the Homepage Header is recommended to provide information about your lab or the lab's research. If included, follow the Homepage Header with a the 2-Column Layout container and, in the "Layout" tab of the editor, apply the "Tertiary-gradient" in the Modifier Class field. In the left column place a combination of Header, Header and Subheader, and Text containers, depending on your content. In the right column, place one Text container. A Button container is also recommended, with the button linked to the Lab's research.
This section of the page should include a 3 or 4-Column Layout container, with a Content Card container in each column. Images will stay in focus on different screen sizes, making them suited to either decorative or informative images.
Read more about Dr. [name]
Each Content Card should contain an image, header and link to the Lab Site page where more information can be found. In the "Layout and style" tab for each card, apply background color Gray 10.
See Lab Members & Alumni There should be a Content Card for each of the three to four most important pages, in order of importance. If content is called out above, such as Research and/or the PI, start this section with the next most important page.
Get in Touch 
This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on.
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About Lauren...
Lab member
Lab member
March 2026
Dr. Smith received a wonderful grand prize.
Read about Dr. Smith's prizeDr. Smith's Publications
Genome-Wide Silencing Captures Obligate Apoptotic Components in Drosophila
Chew, S.,Chen, P., Link, N., Galindo, K., Pogue, K. and Abrams, J.M. July 2009 Nature 460 123-127The Apical Caspase, dronc, Governs Programmed and Unprogrammed Cell Death in Drosophila
Chew, S., Akdemir, F.,Chen, P., Lu, W., Mills, K.,Daish, T.,Kumar, S.,Rodriguez,, A. and Abrams, J.M December 2004 Developmental Cell Volume 7 897-907A Collective Form of Cell Death Requires Homeodomain Interacting Protein Kinase
Link, N., Chen, P., Lu, WJ, Pogue, K., Chuong, A., Mata, M., Checketts, J., Abrams, J.M August 2007 J. Cell Biol 4 (178) 567-74Distinct p53 isoforms code for opposing transcriptional outcomes.
Wylie A, Jones AE, Das S, Lu WJ, Abrams JM, 2022 Jul Dev CellRetrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance.
Tiwari B, Kurtz P, Jones AE, Wylie A, Amatruda JF, Boggupalli DP, Gonsalvez GB, Abrams JM 2017 Oct Curr. Biol. 19 27 3010-3016.e3p53 activity is selectively licensed in the Drosophila stem cell compartment.
Wylie A, Lu WJ, D'Brot A, Buszczak M, Abrams JM 2014 Elife 3 e01530A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans.
Link N, Kurtz P, O'Neal M, Garcia-Hughes G, Abrams JM 2013 Nov Genes Dev. 22 27 2433-8Tango7 directs cellular remodeling by the Drosophila apoptosome.
D'Brot A, Chen P, Vaishnav M, Yuan S, Akey CW, Abrams JM 2013 Aug Genes Dev. 15 27 1650-5Meiotic recombination provokes functional activation of the p53 regulatory network.
Lu WJ, Chapo J, Roig I, Abrams JM 2010 Jun Science 5983 328 1278-81Autophagy Occurs Upstream or Parallel to the Apoptosome During Histolytic Cell Death
Akdemir, F., Farkas, R., Chen, P., Juhasz, G., Medvedova, L., Sass, M., Wang, L., Wang, X., Chittaranian, S., Gorski, SM., Rodriguez, A., Abrams, JM 2006 Development 133 1457-65Drosophila p53 preserves genomic stability by regulating cell death.
Sogame N, Kim M, Abrams JM 2003 Apr Proc. Natl. Acad. Sci. U.S.A. 8 100 4696-701Drosophila p53 binds a damage response element at the reaper locus
Brodsky, M, H. Nordstrom, W, Tsang, G., Kwan, E., Rubin, G.M. and Abrams, J.M. 2000 Cell 101 103-113Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia.
Gu Z, Liu Y, Zhang Y, Cao H, Lyu J, Wang X, Wylie A, Newkirk SJ, Jones AE, Lee M, Botten GA, Deng M, Dickerson KE, Zhang CC, An W, Abrams JM, Xu J, 2021 Apr Nat Genet
January 2025
Meet the newest member of the MAIA lab, Ben Jones, M.D., Ph.D.
April 2024
This is a wonderful article in Newsweek about how MAIA Lab operates.
Read the MAIA Lab articleThis is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on. This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on. This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on. This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on.
A panel of 9 doctors from Children's Health Hospital met this week to discuss childhood diseases.
About project one.
About Project 2
About Project 3
[Note that all this text is editable for individual labs to include the contact info they need]
Email address: example@utsouthwestern.edu
Phone Number: 123-456-7890
Fax Number: 123-456-7890
5323 Harry Hines Blvd.
Dallas, TX 75390
5323 Harry Hines Blvd.
Dallas, TX 75390
[Introduction area for labs to write about how rewarding it is to be part of their team] This is placeholder text. If you are reading this, it is here by mistake and we would appreciate it if you could email us with a link to the page you found it on.
We're always looking to recruit motivated researchers. Explore our positions!
