Sankary Neuroethics Lab

The Sankary Neuroethics Lab at UT Southwestern explores the ethical dimensions of neuroscience and neurosurgical innovation.

Our work focuses on guiding the development of neural devices and brain-computer interfaces, ensuring responsible research and person-centered approaches. Using qualitative interviews, surveys, and consensus-building studies, we examine priorities and expectations of clinical research participants and ethical considerations in early-stage neurotechnology development.

Values: We are dedicated to advancing ethical practices in neuroscience and neurosurgery research. Our research informs the development of neural devices and therapies for the treatment of neurological disorders, addressing questions about participant expectations, return of results, and priorities for the development of novel neurotechnologies.

Meet the Principal Investigator

Lauren Sankary, J.D., M.A., HEC-C

Lauren Sankary, J.D., M.A., HEC-C

Lauren Sankary, J.D., M.A., HEC-C is an Assistant Professor in the UT Southwestern Department of Neurological Surgery and the O'Donnell Brain Institute and a Clinical Ethicist at Clements University Hospital. Prof. Sankary conducts empirical investigations in clinical and translational research ethics with a strong track record of NIH and foundation funding. Her research applies legal, qualitative, and empirical bioethics research methods to investigate ethical issues in clinical research involving vulnerable patient populations, drawing upon her direct experience supporting informed consent as a clinical ethicist and research consent monitor for participants enrolling in innovative neurological research.

Prof. Sankary began her research career with NIH BRAIN Initiative-funded postdoctoral training examining ethical considerations related to explant of implanted neurotechnology and long-term implications of participation in biotechnology research (F32MH115419). She subsequently led two national survey studies investigating unanticipated challenges that arise in obtaining informed consent in research involving cognitively vulnerable patient populations (funded by NINDS 3UH3NS100543-03S1) and multiple stakeholder views on barriers to remote consent practices necessitated by the COVID-19 pandemic (funded by NIA 3P30AG062428-02S2). She also has experience leading community-based research to address mistrust contributing to underrepresentation of minoritized populations in brain related research, supported by a 2023 Cleveland Clinic Caregiver Catalyst Award. Prof. Sankary’s recent study funded by the NIH Office of the Director investigated ethically optimal approaches to capturing participant feedback and informing research participants in early exploratory neurotechnology research in humans (3R01AT011905-02S1). Her current research supported by an Alzheimer’s Association Research Grant (AARG-22-9744622) employs Delphi methods to build expert consensus regarding responsible approaches to sharing Alzheimer’s disease risk information with research participants. Through her research, Prof. Sankary aims to promote alignment between research and community priorities and address barriers to the ethical recruitment and return of value in neurological research.

Current Lab Members

Harshikasai Kellampalli

Harshikasai Kellampalli, B.S.

Harshikasai Kellampalli received her Bachelor of Science degree from the University of California, Los Angeles (UCLA), where she majored in Neuroscience and minored in Global Health. During her undergraduate training, she worked as a Clinical Research Assistant in the UCLA Psychology Department where her work focused on understanding brain–heart synchronization in patients with schizophrenia using electroencephalography (EEG), contributing to research at the intersection of psychophysiology, neural biomarkers, and clinical neuroscience. In addition to her human-subjects research experience, Harshikasai served as a Research Intern in the Lahiri Lab at Cedars-Sinai. There, she conducted animal research examining the neurobiological mechanisms of delirium in neuro–critical care populations, gaining exposure to translational neuroscience and neurocritical care research models.

Her research interests center on patient-centered and patient-driven care in neurology, with a particular focus on the neuroethics of shared decision-making in neurosurgery and pediatric neurology. She is also interested in clinical research methodology, stakeholder-engaged research, neurological health disparities, and the integration of ethical frameworks into complex neurological care and clinical trial design.

Participate in Neuroethics Research

Research Opportunity: Aligning Therapy Development with Patient and Caregiver Priorities in Brain-Computer Interface Research

This is an opportunity to participate in a voluntary research study about understanding the goals of patients, caregivers, clinicians, and researchers with respect to research into new therapies. This study is being conducted by Lauren Sankary, an Assistant Professor in the Department of Neurological Surgery at UT Southwestern Medical Center. This study will be enrolling individuals diagnosed with various health conditions, their caregivers, and experts involved in the clinical care, research, or advocacy related to these conditions, including clinicians, researchers, representatives from funding bodies, and patient advocacy organizations. Participation includes completion of one online survey. Participating in this study is expected to take about 30 minutes (half an hour). If you would like additional information about this study, please contact us at: Email or 214-648-3279 (Monday – Friday, 9 am – 5 pm CST). Completion of the survey using the link below will indicate your agreement to participate after reading the information sheet describing the study in further detail. 

Survey Link: https://redcap.link/AligningPrioritiesBCISurvey 

Thank you for your consideration, and please do not hesitate to contact us if you are interested in learning more about this Institutional Review Board–approved project. 

Lauren Sankary, JD, MA, HEC-C, Assistant Professor, Department of Neurological Surgery 

Principal Investigator 

UT Southwestern Medical Center 

Email Phone: 214-648-3279

Publications

Contact Us

Reach out to us via:

Phone: +1 214 648 8880
Email

Visiting Address:
Charles Cameron Sprague Clinical Science Building
5th floor
5161 Harry Hines Blvd
Dallas, TX, 75390