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Our goal is to identify the metabolic mechanisms that push cells to become cancerous and find new ways to inhibit them.

Our lab works with murine disease models and employs Biochemistry, Molecular and Cell Biology to investigate brain glycogen metabolism and related neurodegenerative diseases.

Our research focuses on how mitochondria are embedded in normal cellular function.

We develop the theory and application of deep learning to improve diagnoses, prognoses and therapy decision making.

Our goal is to better understand the mechanisms that maintain adult tissues and how cancer cells hijack these mechanisms to enable the formation of tumors.

The Munshi Lab is a dedicated group of scientists seeking to identify the molecular drivers of normal cardiac rhythm and disease-associated dysrhythmias.

The mission of the Najafov Lab is to understand the role of cell death in physiology and disease. Our research is focused on necroptosis and how it can be targeted to develop novel strategies for treating cancer.

The Nam lab asks how the shape of an RNA regulates its function. We study the biochemical and structural mechanisms in RNA-mediated gene regulation pathways important for normal and disease states.

The focus of the Neuromuscular Center is the diagnosis and treatment of muscle diseases known as metabolic myopathies, including inherited disorders of muscle fat, carbohydrate, and mitochondrial muscle metabolism.

The main research focus of the Otwinowski lab is on developing computational and statistical
methods and protocols for macromolecular structure determination using X-ray crystallography.

We study how cells duplicate their genomic material and how this process goes awry in disease.

The Pool Lab studies neural circuits that provide a sense of purpose and direction to animal behavior and develops targeted gene therapies to re-engineer their function.

We are driven by the belief that the spatial organization of tissue provides a powerful  window into cell-cell interactions, a crucial component of disease progression and response.

Our lab is broadly focused on the cellular signaling that drives the interactions between the intracellular parasite Toxoplasma gondii and its varied hosts.

In our lab, we investigate the interactions between these multiple pathogens and the immune system.

We are interested in the molecular mechanisms by which nuclear hormone receptors regulate lipid and carbohydrate metabolism in the liver, intestine, pancreatic islet, and central nervous system.

We use statistical analysis of genome sequences drawn from thousands of organisms to distill out general patterns describing the organization of cellular systems and individual proteins.

The Rice Lab uses structure, biochemistry, reconstitution, microscopy, computer modeling, and more to study the molecular mechanisms that generate and regulate microtubule dynamics.

We investigate the mechanism of neurotransmitter release using a variety of biophysical approaches, including NMR spectroscopy, X-ray crystallography, cryo-EM, molecular dynamics simulations and liposome fusion assays.

We study how biomolecular condensates organize gene regulation.