About
The Stopschinski lab investigates molecular and cellular mechanisms that drive neurodegeneration in Alzheimer’s Disease and other tauopathies with the goal to find new diagnostic and therapeutic approaches for these conditions.
The lab has two fundamental areas of interest:
- To study the role of heparan sulfate proteoglycans and other cell surface receptors in cellular tau uptake.
- To study the role of neuroinflammation in the initiation and progression of tauopathies in cell and mouse models.
We apply a range of methods including protein biochemistry, cellular and molecular biology, pre-clinical mouse models, and analysis of patient-derived samples.