Liu (Shixuan) Lab

We leverage our knowledge of fundamental neuroscience to create wearable bidirectional brain-machine interfaces for the restoration and assistance of upper limb sensation and movement in people with paralysis.

We use neuroimaging, neuromodulation, and behavioral experimentation to elucidate the brain circuits and mechanisms that support language and cognition, and to understand how these circuits differ in neurodevelopmental conditions such as autism. We are particularly interested in the role of cerebro-cerebellar circuits in language and cognition across development and disorders.

The work of the Chemical Advanced Neuroimaging Lab is focused on developing state-of-the-art proton MRS and MRSI methods and leveraging these tools to answer key clinical questions and improve the quality of neurologic care.

The Calvier Lab's research focuses on endothelial modulation as a therapeutic approach to inflammatory diseases.

Dr. Zhu has investigated disease mechanisms and attempted to develop novel therapeutic strategies for tumor suppressor gene (TSG), syndrome-associated tumors in the nervous system, and neuropsychiatric disorders.

The Ishii Laboratory is interested in understanding the bidirectional relationship between brain function and systemic metabolism with an emphasis on metabolic deficits in Alzheimer’s disease and how it differs from normal aging. Our laboratory focuses on generating hypotheses derived from open questions in clinical neurology and neuroendocrinology, testing these hypotheses using molecular genetics and neuroscience techniques in the laboratory, and whenever possible verifying these findings in clinically relevant human research studies. 

MUDIA Lab is focused on developing novel quantitative MRI techniques and analysis methods on CNS and musculoskeletal system. 

The Noch Lab is a basic and translational research laboratory focused on identifying novel strategies to target metabolic vulnerabilities in glioma.

The Lin Lab studies the transformation of brief experiences into enduring memories, their impact on behaviors, and the differing responses seen in both healthy and diseased conditions. Utilizing a multidisciplinary approach, our research explores how experience-induced genetic programs establish connections between experiences and synaptic modifications within neural circuits, ultimately driving persistent behavioral changes.