Our lab is creating better experimental models that reveal how cancer cells metastasize and evade our immune system. We use these models to develop new drugs that engage our immune system to kill cancer cells.

• To understand how kidney cancer develops at the molecular level.
• To translate our findings into new treatments for kidney cancer patients.
• To train the next generation of physicians and scientists.

The James Kim Lab examines the communication between epithelia and stroma through the lens of fundamental developmental pathways such as Hedgehog, Wnt, and Notch pathways.

Chung Lab uses primary human specimens, patient-derived xenograft models, and genetically engineered mouse models to study the molecular mechanisms underlying disease stem cell function in hematologic malignancies.

 In prior work, my laboratory focused on identifying novel mechanisms of therapy-resistance and progression in breast, prostate and ovarian cancer. 

The Reddy Lab focuses on restoring effective antigen presentation to enhance anti-tumor immunity in breast cancers.