Tu C, Caudal A, Liu Y, Narayan SM, Wu JC. Modeling heart rhythm using human engineered heart tissues. Nat Protoc. 2025 Aug 1;. doi: 10.1038/s41596-025-01217-w. [Epub ahead of print] Review. PubMed PMID: 40750715.
Zhang H, Thai PN, Shivnaraine RV, Ren L, Wu X, Siepe DH, Liu Y, Tu C, Shin HS, Caudal A, Mukherjee S, Leitz J, Wen WTL, Liu W, Zhu W, Chiamvimonvat N, Wu JC. Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target. Cell. 2024 Dec 12;187(25):7143-7163.e22. doi: 10.1016/j.cell.2024.09.034. Epub 2024 Oct 15. PubMed PMID: 39413786; PubMed Central PMCID: PMC11645214.
Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA, Yang H, Abilez OJ, Lyu X, Narayan SM, Mestroni L, Taylor MRG, Recchia FA, Wu JC. Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Nat Biomed Eng. 2024 Apr;8(4):479-494. doi: 10.1038/s41551-023-01134-x. Epub 2023 Nov 27. PubMed PMID: 38012305; PubMed Central PMCID: PMC11088531.
Tu C, Liu Y, Williams DR, Wu JC. A transcriptomic atlas of drug-induced endothelial dysfunction in human endothelial cells. J Mol Cell Cardiol. 2022 Dec;173:115-117. doi: 10.1016/j.yjmcc.2022.10.002. Epub 2022 Oct 27. PubMed PMID: 36327770; PubMed Central PMCID: PMC10902208.
Strimaityte D, Tu C, Yanez A, Itzhaki I, Wu H, Wu JC, Yang H. Contractility and Calcium Transient Maturation in the Human iPSC-Derived Cardiac Microfibers. ACS Appl Mater Interfaces. 2022 Aug 10;14(31):35376-35388. doi: 10.1021/acsami.2c07326. Epub 2022 Jul 28. PubMed PMID: 35901275; PubMed Central PMCID: PMC9780031.
Caudal A, Ren L, Tu C, Wu JC. Human induced pluripotent stem cells for studying mitochondrial diseases in the heart. FEBS Lett. 2022 Jul;596(14):1735-1745. doi: 10.1002/1873-3468.14444. Epub 2022 Jul 11. Review. PubMed PMID: 35788991; PubMed Central PMCID: PMC9668541.
Zhang JZ, Zhao SR, Tu C, Pang P, Zhang M, Wu JC. Protocol to measure contraction, calcium, and action potential in human-induced pluripotent stem cell-derived cardiomyocytes. STAR Protoc. 2021 Dec 17;2(4):100859. doi: 10.1016/j.xpro.2021.100859. eCollection 2021 Dec 17. PubMed PMID: 34746854; PubMed Central PMCID: PMC8551496.
Yang H, Shao N, Holmström A, Zhao X, Chour T, Chen H, Itzhaki I, Wu H, Ameen M, Cunningham NJ, Tu C, Zhao MT, Tarantal AF, Abilez OJ, Wu JC. Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue. Cardiovasc Res. 2021 Jul 27;117(9):2125-2136. doi: 10.1093/cvr/cvaa281. PubMed PMID: 33002105; PubMed Central PMCID: PMC8318103.
Tu C, Cunningham NJ, Zhang M, Wu JC. Human Induced Pluripotent Stem Cells as a Screening Platform for Drug-Induced Vascular Toxicity. Front Pharmacol. 2021;12:613837. doi: 10.3389/fphar.2021.613837. eCollection 2021. Review. PubMed PMID: 33790786; PubMed Central PMCID: PMC8006367.
Tu C, Mezynski R, Wu JC. Improving the engraftment and integration of cell transplantation for cardiac regeneration. Cardiovasc Res. 2020 Mar 1;116(3):473-475. doi: 10.1093/cvr/cvz237. PubMed PMID: 31504255; PubMed Central PMCID: PMC7252439.
Allen ACB, Barone E, Momtahan N, Crosby CO, Tu C, Deng W, Polansky K, Zoldan J. Temporal Impact of Substrate Anisotropy on Differentiating Cardiomyocyte Alignment and Functionality. Tissue Eng Part A. 2019 Oct;25(19-20):1426-1437. doi: 10.1089/ten.TEA.2018.0258. Epub 2019 Aug 20. PubMed PMID: 30727863; PubMed Central PMCID: PMC6939589.
Zhang H, Tian L, Shen M, Tu C, Wu H, Gu M, Paik DT, Wu JC. Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis. Circ Res. 2019 Aug 16;125(5):552-566. doi: 10.1161/CIRCRESAHA.119.315491. Epub 2019 Jul 10. PubMed PMID: 31288631; PubMed Central PMCID: PMC6768436.
Crosby CO, Valliappan D, Shu D, Kumar S, Tu C, Deng W, Parekh SH, Zoldan J. Quantifying the Vasculogenic Potential of Induced Pluripotent Stem Cell-Derived Endothelial Progenitors in Collagen Hydrogels. Tissue Eng Part A. 2019 May;25(9-10):746-758. doi: 10.1089/ten.TEA.2018.0274. Epub 2019 May 2. PubMed PMID: 30618333; PubMed Central PMCID: PMC6535961.
Tu C, Zoldan J. Moving iPSC-Derived Cardiomyocytes Forward to Treat Myocardial Infarction. Cell Stem Cell. 2018 Sep 6;23(3):322-323. doi: 10.1016/j.stem.2018.08.011. PubMed PMID: 30193131.
Tu C, Allen A, Deng W, Conroy O, Nambiar M, Zoldan J. Commonly used thiol-containing antioxidants reduce cardiac differentiation and alter gene expression ratios of sarcomeric isoforms. Exp Cell Res. 2018 Sep 1;370(1):150-159. doi: 10.1016/j.yexcr.2018.06.017. Epub 2018 Jun 18. PubMed PMID: 29920245.
Tu C, Chao BS, Wu JC. Strategies for Improving the Maturity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circ Res. 2018 Aug 17;123(5):512-514. doi: 10.1161/CIRCRESAHA.118.313472. PubMed PMID: 30355143; PubMed Central PMCID: PMC6392006.
Tu C, Xu R, Koleti M, Zoldan J. Glycogen synthase kinase-3 inhibition sensitizes human induced pluripotent stem cells to thiol-containing antioxidants induced apoptosis. Stem Cell Res. 2017 Aug;23:182-187. doi: 10.1016/j.scr.2017.07.019. Epub 2017 Jul 22. PubMed PMID: 28772167.
Tu C, Santo L, Mishima Y, Raje N, Smilansky Z, Zoldan J. Monitoring protein synthesis in single live cancer cells. Integr Biol (Camb). 2016 May 16;8(5):645-53. doi: 10.1039/c5ib00279f. Epub 2016 Mar 9. PubMed PMID: 26956582.
Baek K, Tu C, Zoldan J, Suggs L. Gene transfection for stem cell therapy. Current Stem Cell Reports. 2016 January; 2(1):52-61. doi: 10.1007/s40778-016-0029-5.
Tu C, Das S, Baker AB, Zoldan J, Suggs LJ. Nanoscale strategies: treatment for peripheral vascular disease and critical limb ischemia. ACS Nano. 2015;9(4):3436-52. doi: 10.1021/nn507269g. Epub 2015 Apr 10. Review. PubMed PMID: 25844518; PubMed Central PMCID: PMC5494973.