Publications

Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair

Chiang JC, Shang Z, Rosales T, Cai L, Chen WM, Cai F, Vu H, Minna JD, Ni M, Davis AJ, Timmerman RD, DeBerardinis RJ, Zhang Y 2025 Mar Science Advances 11

Concerning Safety and Efficacy of Concurrent and Consolidative Durvalumab With Thoracic Radiation Therapy in PDL1-Unselected Stage III Non-Small Cell Lung Cancer: Brief Report

Zhang Y, Iyengar P, Montalvo S, Westover KD, Rashdan S, Donthireddy K, Kim J, Dowell JE, Drapkin B, Bhalla S, Chukwuma C, Nadeem U, Ahn C, Timmerman RD, Gerber DE 2025 Jan International Journal of Radiation Oncology Biology Physics 121 68-74

Concurrent and Consolidative Carboplatin Plus Nab-Paclitaxel or Paclitaxel in Locally Advanced NSCLC: A Multicenter, Randomized Clinical Trial

Zhang Y, Laine AM, Iyengar P, Westover KD, Dowell JE, Hughes RS, Christie A, Mickel T, Attia A, Villaruz L, Chen Y, Spigel DR, Socinski MA, Timmerman RD, Gerber DE 2025 International Journal of Radiation Oncology Biology Physics 122 374-382

Adapt-On-Demand: A Novel Strategy for Personalized Adaptive Radiation Therapy for Locally Advanced Lung Cancer

Li R, Zhuang T, Montalvo S, Wang K, Parsons D, Zhang Y, Iyengar P, Wang J, Godley A, Cai B, Lin MH, Westover K 2024 Sep Practical Radiation Oncology 14 e395-e406

Mitochondrial complex I promotes kidney cancer metastasis

Bezwada D, Perelli L, Lesner NP, Cai L, Brooks B, Wu Z, Vu H, Sondhi V, Cassidy DL, Kasitinon SY, Kelekar S, Cai F, Aurora AB, Patrick M, Leach A, Ghandour R, Zhang Y, Do D, McDaniel P, Sudderth JA, Dumesnil D, House S, Rosales TI, Poole AM, Lotan Y, Woldu S, Bagrodia A, Meng X, Cadeddu JA, Mishra P, Garcia Bermudez J, Pedrosa I, Kapur P, Courtney KD, Malloy CR, Genovese G, Margulis V, DeBerardinis RJ 2024 Aug Nature 633 923-931

Concerning safety and efficacy of concurrent and consolidative durvalumab with thoracic radiotherapy in PDL1-unselected stage III non-small cell lung cancer: brief report

Zhang Y, Iyengar P, Montalvo SK, Westover KD, Rashdan S, Donthireddy KR, Kim J, Dowell JE, Drapkin BJ, Bhalla S, Chukwuma C, Nadeem U, Ahn C, Timmerman R, Gerber DE 2024 Aug International Journal of Radiation Oncology Biology Physics S0360-3016 03177-8

Beyond conventional bounds: Surpassing system limits for stereotactic ablative (SAbR) lung radiotherapy using CBCT-based adaptive planning system

Gonzalez Y, Visak J, Overman L, Liao CY, Yen A, Zhuang T, Cai B, Godley A, Zhang Y, Timmerman R, Iyengar P, Westover K, Parsons D, Lin MH 2024 Aug Journal of applied clinical medical physics 25

Electron transport chain inhibition increases cellular dependence on purine transport and salvage

Wu Z, Bezwada D, Cai F, Harris RC, Ko B, Sondhi V, Pan C, Vu HS, Nguyen PT, Faubert B, Cai L, Chen H, Martin-Sandoval M, Do D, Gu W, Zhang Y, Zhang Y, Brooks B, Kelekar S, Zacharias LG, Oaxaca KC, Patricio JS, Mathews TP, Garcia-Bermudez J, Ni M, DeBerardinis RJ 2024 Jul Cell Metabolism 36 1504-1520.e9

Elucidating the Mechanism of Radiation Therapy on Mesenchymal Cell Fate in Preventing Heterotopic Ossification

Hsieh M, Choi JH, Korlakunta S, Zhang Y, Levi B 2024 Jun Annals of Surgery

Predictive Clinical Factors for Geometric Response to Adaptive Radiotherapy in Thoracic Malignancy

Li R, Montalvo SK, Wang K, Parsons D, Zhang Y, Iyengar P, Wang J, Godley A, Cai B, Lin M 2024 Apr Practical Radiation Oncology S1879-8500

An AI-based approach for modeling the synergy between radiotherapy and immunotherapy

Peng H, Moore C, Zhang Y, Saha D, Jiang S, Timmerman R 2024 Scientific reports 14

Systemic immune parameters after prior radiation therapy in patients receiving immune checkpoint inhibitors

Mundra V, Yang Y, von Itzstein MS, Fattah F, Gonugunta AS, Hannan R, Pop LM, Zhang Y, Wang Y, Sheffield T, Xie Y, Dowell JE, Homsi J, Rashdan S, Park J, Li Q, Wakeland EK, Gerber DE 2023 Aug Translational Oncology 34

DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism

Chen WM, Chiang JC, Shang Z, Palchik G, Newman C, Zhang Y, Davis AJ, Lee H, Chen BP 2023 Mar EMBO Journal 42

In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

Kaushik AK, Tarangelo A, Boroughs LK, Ragavan M, Zhang Y, Wu CY, Li X, Ahumada K, Chiang JC, Tcheuyap VT, Saatchi F, Do QN, Yong C, Rosales T, Stevens C, Rao AD, Faubert B, Pachnis P, Zacharias LG, Vu H, Cai F, Mathews TP, Genovese G, Slusher BS, Kapur P, Sun X, Merritt ME, Brugarolas J, DeBerardinis RJ 2022 Science Advances 8

Stereotactic Ablative Radiation Therapy for Oligoprogressive Renal Cell Carcinoma

Schoenhals JE, Mohamad O, Christie A, Zhang Y, Li D, Singla N, Bowman I, Arafat W, Hammers H, Courtney K, Cole S, Bagrodia A, Margulis V, Desai N, Garant A, Choy H, Timmerman R, Brugarolas J, Hannan R 2021 Sep Advances in Radiation Oncology 6

Cosmetic Outcomes of a Phase 1 Dose Escalation Study of 5-Fraction Stereotactic Partial Breast Irradiation for Early Stage Breast Cancer

Rahimi A, Morgan HE, Kim DW, Zhang Y, Leitch M, Wooldridge RD, Goudreau S, Haley BB, Rao R, Rivers AK, Spangler AE, Jones RT, Stevenson S, Staley J, Albuquerque K, Ahn C, Neufeld S, Alluri PG, Ding C, Garwood D, Seiler S, Zhao B, Gu X, Timmerman R 2021 Jul International Journal of Radiation Oncology Biology Physics 110 772-782

Risk Factors for Fat Necrosis After Stereotactic Partial Breast Irradiation for Early-Stage Breast Cancer in a Phase 1 Clinical Trial

Rahimi A, Zhang Y, Kim DW, Morgan H, Hossain F, Leitch M, Wooldridge RD, Seiler S, Goudreau S, Haley BB, Rao R, Rivers AK, Spangler AE, Ahn C, Stevenson S, Staley J, Albuquerque K, Ding C, Gu X, Zhao B, Timmerman R 2020 Nov International Journal of Radiation Oncology Biology Physics 108 697-706

Stereotactic Ablative Radiation Therapy (SAbR) Used to Defer Systemic Therapy in Oligometastatic Renal Cell Cancer

Zhang Y, Schoenhals J, Christie A, Mohamad O, Wang C, Bowman I, Singla N, Hammers H, Courtney K, Bagrodia A, Margulis V, Desai N, Garant A, Choy H, Timmerman R, Brugarolas J, Hannan R 2019 Oct International Journal of Radiation Oncology Biology Physics 105 367-375

Global Phosphoproteomic Analysis of Insulin/Akt/mTORC1/S6K Signaling in Rat Hepatocytes

Zhang Y, Zhang Y, Yu Y 2017 Aug Journal of Proteome Research 16 2825-2835

Multi-objective radiomics model for predicting distant failure in lung SBRT

Zhou Z, Folkert M, Iyengar P, Westover K, Zhang Y, Choy H, Timmerman R, Jiang S, Wang J 2017 May Physics in medicine and biology 62 4460-4478

Predicting distant failure in early stage NSCLC treated with SBRT using clinical parametersPredicting distant failure in lung SBRT

Zhou Z, Folkert M, Cannon N, Iyengar P, Westover K, Zhang Y, Choy H, Timmerman R, Yan J, Xie XJ, Jiang S, Wang J 2016 Jun Radiotherapy and Oncology 119 501-504

Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone

Zhang Y, Fang F, Goldstein JL, Brown MS, Zhao TJ 2015 Jan Proceedings of the National Academy of Sciences of the United States of America 112 1226-1231

Small-molecule inducers of Aβ-42 peptide production share a common mechanism of action.

Bettayeb K, Oumata N, Zhang Y, Luo W, Bustos V, Galons H, Greengard P, Meijer L, Flajolet M 2012 Dec FASEB Journal 26 5115-5123

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

Owen JL, Zhang Y, Bae SH, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MS 2012 Oct Proceedings of the National Academy of Sciences of the United States of America 109 16184-16189

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

Owen JL, Zhang Y, Bae SH, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MS 2012 Oct Proceedings of the National Academy of Sciences of the United States of America 109 16184 - 16189

Premastication: The second arm of infant and young child feeding for health and survival?

Pelto GH, Zhang Y, Habicht JP 2010 Jan Maternal and Child Nutrition 6 4-18