Our Research Focus
Dr. Brown's research, which is supported by several NIH institutes as well as private foundations, focuses on comorbidities of mood disorders, including medical illness, cortisol elevation, and substance abuse.
Mood disorders associated with general medical conditions:
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Corticosteroid effects on the human brain: We examine the use of glutamate release inhibitors as neuroprotective agents against stress or corticosteroid-induced hippocampal changes.
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Depression in asthma patients: We have ongoing research examining the treatment of depressed asthma patients.
Mood disorders with comorbid substance abuse bipolar disorder has high rates of substance abuse:
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We have successfully completed and continue to launch investigations into the efficacy of aripiprazole, pregnenolone, and citicoline for patients navigating bipolar disorder alongside alcohol or cannabis dependence.